Literature DB >> 26575226

Targeting transcription is no longer a quixotic quest.

Anna K Mapp1, Rachel Pricer1, Steven Sturlis1.   

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Year:  2015        PMID： 26575226      PMCID： PMC5076862          DOI： 10.1038/nchembio.1962

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  25 in total

1.  Genetic regulatory mechanisms in the synthesis of proteins.

Authors:  F JACOB; J MONOD
Journal:  J Mol Biol       Date:  1961-06       Impact factor: 5.469

Review 2.  Fine-tuning multiprotein complexes using small molecules.

Authors:  Andrea D Thompson; Amanda Dugan; Jason E Gestwicki; Anna K Mapp
Journal:  ACS Chem Biol       Date:  2012-07-23       Impact factor: 5.100

Review 3.  Molecular mechanisms of ETS transcription factor-mediated tumorigenesis.

Authors:  Adwitiya Kar; Arthur Gutierrez-Hartmann
Journal:  Crit Rev Biochem Mol Biol       Date:  2013-09-25       Impact factor: 8.250

4.  Allostery within a transcription coactivator is predominantly mediated through dissociation rate constants.

Authors:  Sarah L Shammas; Alexandra J Travis; Jane Clarke
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-04       Impact factor: 11.205

Review 5.  Small-molecule inhibitors of protein-protein interactions: progressing toward the reality.

Authors:  Michelle R Arkin; Yinyan Tang; James A Wells
Journal:  Chem Biol       Date:  2014-09-18

6.  Transcriptional amplification in tumor cells with elevated c-Myc.

Authors:  Charles Y Lin; Jakob Lovén; Peter B Rahl; Ronald M Paranal; Christopher B Burge; James E Bradner; Tong Ihn Lee; Richard A Young
Journal:  Cell       Date:  2012-09-28       Impact factor: 41.582

7.  Inhibitors of difficult protein-protein interactions identified by high-throughput screening of multiprotein complexes.

Authors:  Laura C Cesa; Srikanth Patury; Tomoko Komiyama; Atta Ahmad; Erik R P Zuiderweg; Jason E Gestwicki
Journal:  ACS Chem Biol       Date:  2013-07-09       Impact factor: 5.100

8.  Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes.

Authors:  Diwakar R Pattabiraman; Crystal McGirr; Konstantin Shakhbazov; Valerie Barbier; Keerthana Krishnan; Pamela Mukhopadhyay; Paula Hawthorne; Ann Trezise; Jianmin Ding; Sean M Grimmond; Peter Papathanasiou; Warren S Alexander; Andrew C Perkins; Jean-Pierre Levesque; Ingrid G Winkler; Thomas J Gonda
Journal:  Blood       Date:  2014-03-04       Impact factor: 22.113

9.  A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.

Authors:  Marius S Pop; Nicolas Stransky; Colin W Garvie; Jean-Philippe Theurillat; Emily C Hartman; Timothy A Lewis; Cheng Zhong; Elizabeth K Culyba; Fallon Lin; Douglas S Daniels; Raymond Pagliarini; Lucienne Ronco; Angela N Koehler; Levi A Garraway
Journal:  Mol Cancer Ther       Date:  2014-04-15       Impact factor: 6.261

10.  Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors.

Authors:  Stephen E Leonard; A C Register; Ratika Krishnamurty; Gabriel J Brighty; Dustin J Maly
Journal:  ACS Chem Biol       Date:  2014-07-02       Impact factor: 5.100
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  10 in total

Review 1.  Personalized and targeted therapy of esophageal squamous cell carcinoma: an update.

Authors:  Yongjing Liu; Zhaohui Xiong; Andrea Beasley; Thomas D'Amico; Xiaoxin Luke Chen
Journal:  Ann N Y Acad Sci       Date:  2016-07-11       Impact factor: 5.691

2.  Electron-deficient p-benzoyl-l-phenylalanine derivatives increase covalent chemical capture yields for protein-protein interactions.

Authors:  Cassandra M Joiner; Meghan E Breen; Anna K Mapp
Journal:  Protein Sci       Date:  2019-04-29       Impact factor: 6.725

3.  Small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity represents a potential strategy for anticancer therapy.

Authors:  Virginie Gervais; Isabelle Muller; Pierre-Olivier Mari; Amandine Mourcet; Kumar Tekwani Movellan; Pascal Ramos; Julien Marcoux; Valérie Guillet; Sumaira Javaid; Odile Burlet-Schiltz; Georges Czaplicki; Alain Milon; Giuseppina Giglia-Mari
Journal:  J Biol Chem       Date:  2018-08-01       Impact factor: 5.157

Review 4.  Systematic Targeting of Protein-Protein Interactions.

Authors:  Ashley E Modell; Sarah L Blosser; Paramjit S Arora
Journal:  Trends Pharmacol Sci       Date:  2016-06-04       Impact factor: 14.819

Review 5.  Selective Modulation of Dynamic Protein Complexes.

Authors:  Julie M Garlick; Anna K Mapp
Journal:  Cell Chem Biol       Date:  2020-08-11       Impact factor: 8.116

6.  Unexpected specificity within dynamic transcriptional protein-protein complexes.

Authors:  Matthew J Henley; Brian M Linhares; Brittany S Morgan; Tomasz Cierpicki; Carol A Fierke; Anna K Mapp
Journal:  Proc Natl Acad Sci U S A       Date:  2020-10-19       Impact factor: 11.205

Review 7.  Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and Treatment.

Authors:  Rudolph E Willis
Journal:  Int J Mol Sci       Date:  2016-09-14       Impact factor: 5.923

8.  Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators.

Authors:  Andrew R Henderson; Matthew J Henley; Nicholas J Foster; Amanda L Peiffer; Matthew S Beyersdorf; Kevon D Stanford; Steven M Sturlis; Brian M Linhares; Zachary B Hill; James A Wells; Tomasz Cierpicki; Charles L Brooks; Carol A Fierke; Anna K Mapp
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-20       Impact factor: 11.205

9.  Norstictic Acid Is a Selective Allosteric Transcriptional Regulator.

Authors:  Julie M Garlick; Steven M Sturlis; Paul A Bruno; Joel A Yates; Amanda L Peiffer; Yejun Liu; Laura Goo; LiWei Bao; Samantha N De Salle; Giselle Tamayo-Castillo; Charles L Brooks; Sofia D Merajver; Anna K Mapp
Journal:  J Am Chem Soc       Date:  2021-06-17       Impact factor: 15.419

Review 10.  Therapeutic Targeting of the General RNA Polymerase II Transcription Machinery.

Authors:  Ryan D Martin; Terence E Hébert; Jason C Tanny
Journal:  Int J Mol Sci       Date:  2020-05-09       Impact factor: 5.923
  10 in total

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