Literature DB >> 26564326

Diagnostic Reference Levels of CT Radiation Dose in Whole-Body PET/CT.

Ngoneh Jallow1, Paul Christian2, John Sunderland3, Michael Graham3, John M Hoffman2, Jonathon A Nye4.   

Abstract

UNLABELLED: The role of CT in PET/CT imaging includes acquisition techniques for diagnostic, anatomic localization, and attenuation correction purposes. Diagnostic reference levels of the volumetric CT dose index (CTDIvol) are available for dedicated CT procedures on selected body regions, but similar reference levels for whole-body CT used in PET/CT examinations are limited. This work reports CTDIvol values from sites that conduct whole-body oncologic PET/CT examinations and participated in the scanner validation program of the Society of Nuclear Medicine and Molecular Imaging Clinical Trials Network.
METHODS: From 2010 to 2014, a total of 154 sites submitted CT acquisition parameters used in their clinical (18)F-FDG PET/CT oncology protocols. From these parameters, the CTDIvol was estimated using the ImPACT CTDI dosimetry tables. Histograms of CTDIvol values were created for each year, and descriptive statistics, including mean, median, and 75th percentile, were reported. Repeated-measures ANOVA was performed to determine whether significant differences occurred between reporting years.
RESULTS: A wide range of technical parameters was reported, most notably in tube current. Between 2010 and 2014, the median CTDIvol ranged from 4.9 to 6.2 mGy and the 75th percentile from 9.7 to 10.2 mGy. There was no significant change in CTDIvol between reporting years (repeated-measures ANOVA, P = 0.985).
CONCLUSION: The 75th percentile CTDIvol reported in this work was 9.8 mGy averaged over all reporting years. These data provide a resource for establishing CTDIvol reference values specific to performing CT in PET/CT whole-body examinations. The wide ranges of CT acquisition parameters reported by sites suggest that CTDIvol reference levels may be beneficial for optimization of CT protocols.
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Keywords:  CTDI; PET/CT; dosimetry

Mesh:

Substances:

Year:  2015        PMID: 26564326     DOI: 10.2967/jnumed.115.160465

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  4 in total

1.  Patient dosimetry audit for establishing local diagnostic reference levels for nuclear medicine CT.

Authors:  Matthew Gardner; Ngonidzashe M Katsidzira; Erin Ross; Elizabeth A Larkin
Journal:  Br J Radiol       Date:  2017-01-19       Impact factor: 3.039

2.  A Nordic survey of CT doses in hybrid PET/CT and SPECT/CT examinations.

Authors:  Natalie A Bebbington; Bryan T Haddock; Henrik Bertilsson; Eero Hippeläinen; Ellen M Husby; Virpi I Tunninen; Marcus Söderberg
Journal:  EJNMMI Phys       Date:  2019-12-16

3.  National Diagnostic Reference Level (DRL) for nuclear medicine computed tomography-positron emission tomography hybrid imaging studies for kuwait population: second phase dose audit-2019.

Authors:  Michael Masoomi; Iman Al-Shammeri; Latifah Al-Kandari; Hany Elrahman; Jehan Al-Shammeri
Journal:  BJR Open       Date:  2021-11-24

4.  Effective dose estimation for oncological and neurological PET/CT procedures.

Authors:  Josep M Martí-Climent; Elena Prieto; Verónica Morán; Lidia Sancho; Macarena Rodríguez-Fraile; Javier Arbizu; María J García-Velloso; José A Richter
Journal:  EJNMMI Res       Date:  2017-04-24       Impact factor: 3.138

  4 in total

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