Subha Soumya Dany1, Pritam Mohanty2, Pradeep Tangade3, Prashant Rajput1, Manu Batra4. 1. Post-Graduate Student, Department of Public Health Dentistry, Kothiwal Dental College & Research Centre , Kanth Road, Moradabad, Uttar Pradesh, India . 2. Reader, Department of Orthodontics & Dentofacial Orthopaedics, Kalinga Institute of Dental Sciences, KIIT University , Bhubaneswar, Odisha, India . 3. Professor & Head, Department of Public Health Dentistry, Kothiwal Dental College & Research Centre , Kanth Road, Moradabad, Uttar Pradesh, India . 4. Assistant Professor, Department of Public Health Dentistry, Teerthanker Mahaveer Dental college , Delhi Road, Moradabad, Uttar Pradesh, India .
Abstract
BACKGROUND:Chlorhexidine mouthwash has earned eponym of gold standard to treat and/or prevent periodontal diseases. However, the present study was carried out to explore an alternative herbal mouthwash. AIM: To compare the anti-plaque and anti-gingivitis efficacy of a 0.25% lemongrass oil mouthwash to that of 0.2% chlorhexidine mouthwash. MATERIALS AND METHODS: A double-blinded parallel designed clinical trial with 60 subjects was taken for the study. Baseline plaque index (PI) & gingival index (GI) score was recorded. Oral prophylaxis was done and the plaque score was set at zero. Then, subjects were randomly allocated into 3 groups (N=20 in each): 0.25% lemongrass oil mouthwash, 0.2% chlorhexidine mouthwash and oral prophylaxis only. Subjects were asked to swish with respective mouthwash twice daily for 21 days. Subjects were again re-evaluated on 14(th) and 21(st) day for GI and PI. Comparison of the mean difference among the variables was performed by parametric tests. RESULTS: Lemongrass oil mouthwash group showed highest reduction in GI &; PI at both 14(th) and 21(st) day, which was statistically significant (p≤0.05). CONCLUSION: Lemongrass oil mouthwash can also be used as a good herbal alternative to chlorhexidine mouthwash, so further studies are needed.
RCT Entities:
BACKGROUND:Chlorhexidine mouthwash has earned eponym of gold standard to treat and/or prevent periodontal diseases. However, the present study was carried out to explore an alternative herbal mouthwash. AIM: To compare the anti-plaque and anti-gingivitis efficacy of a 0.25% lemongrass oil mouthwash to that of 0.2% chlorhexidine mouthwash. MATERIALS AND METHODS: A double-blinded parallel designed clinical trial with 60 subjects was taken for the study. Baseline plaque index (PI) & gingival index (GI) score was recorded. Oral prophylaxis was done and the plaque score was set at zero. Then, subjects were randomly allocated into 3 groups (N=20 in each): 0.25% lemongrass oil mouthwash, 0.2% chlorhexidine mouthwash and oral prophylaxis only. Subjects were asked to swish with respective mouthwash twice daily for 21 days. Subjects were again re-evaluated on 14(th) and 21(st) day for GI and PI. Comparison of the mean difference among the variables was performed by parametric tests. RESULTS:Lemongrass oil mouthwash group showed highest reduction in GI & PI at both 14(th) and 21(st) day, which was statistically significant (p≤0.05). CONCLUSION:Lemongrass oil mouthwash can also be used as a good herbal alternative to chlorhexidine mouthwash, so further studies are needed.
Authors: C G Kevil; H Pruitt; T J Kavanagh; J Wilkerson; F Farin; D Moellering; V M Darley-Usmar; D C Bullard; R P Patel Journal: FASEB J Date: 2004-06-04 Impact factor: 5.191