Literature DB >> 26543794

What Happens When Children with Fetal Alcohol Spectrum Disorders Become Adults?

Eileen M Moore1, Edward P Riley1.   

Abstract

The range of structural abnormalities and functional deficits caused by prenatal alcohol exposure (PAE) are referred to as fetal alcohol spectrum disorders (FASDs). The disabilities associated with FASDs are said to be lifelong, but we know relatively little regarding outcomes beyond childhood and adolescence. Many of physical, brain, and neurobehavioral features that are present in children with FASDs will endure to adulthood. However, some features may diminish or change over time. Furthermore, secondary disabilities, such as school drop outs, trouble with the law, and substance/alcohol abuse problems are common in young adults with FASDs. The health consequences associated with PAE in the human adult are unknown, but animal models suggest that they may be more susceptible to chronic diseases such as hypertension, diabetes, immune dysfunction, and cancer. More research is needed to understand the lasting effects of PAE on adults and the developmental trajectories of FASDs.

Entities:  

Keywords:  adult; behavior; cognition; fetal alcohol spectrum disorders; health

Year:  2015        PMID: 26543794      PMCID: PMC4629517          DOI: 10.1007/s40474-015-0053-7

Source DB:  PubMed          Journal:  Curr Dev Disord Rep


  56 in total

1.  Specific impairments in self-regulation in children exposed to alcohol prenatally.

Authors:  P W Kodituwakku; N S Handmaker; S K Cutler; E K Weathersby; S D Handmaker
Journal:  Alcohol Clin Exp Res       Date:  1995-12       Impact factor: 3.455

2.  Verbal and nonverbal memory in adults prenatally exposed to alcohol.

Authors:  Claire D Coles; Mary Ellen Lynch; Julie A Kable; Katrina C Johnson; Felicia C Goldstein
Journal:  Alcohol Clin Exp Res       Date:  2010-03-03       Impact factor: 3.455

3.  Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis.

Authors:  Albert E Chudley; Julianne Conry; Jocelynn L Cook; Christine Loock; Ted Rosales; Nicole LeBlanc
Journal:  CMAJ       Date:  2005-03-01       Impact factor: 8.262

Review 4.  Cognitive reserve in ageing and Alzheimer's disease.

Authors:  Yaakov Stern
Journal:  Lancet Neurol       Date:  2012-11       Impact factor: 44.182

5.  Immune deficiency in fetal alcohol syndrome.

Authors:  S Johnson; R Knight; D J Marmer; R W Steele
Journal:  Pediatr Res       Date:  1981-06       Impact factor: 3.756

6.  Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections.

Authors:  Jodi McGill; David K Meyerholz; Michelle Edsen-Moore; Betty Young; Ruth A Coleman; Annette J Schlueter; Thomas J Waldschmidt; Robert T Cook; Kevin L Legge
Journal:  J Immunol       Date:  2009-06-15       Impact factor: 5.422

7.  Longitudinal MRI reveals altered trajectory of brain development during childhood and adolescence in fetal alcohol spectrum disorders.

Authors:  Sarah Treit; Catherine Lebel; Lauren Baugh; Carmen Rasmussen; Gail Andrew; Christian Beaulieu
Journal:  J Neurosci       Date:  2013-06-12       Impact factor: 6.167

8.  Growth retardation in fetal alcohol syndrome. Unresponsiveness to growth-promoting hormones.

Authors:  S Castells; E Mark; F Abaci; E Schwartz
Journal:  Dev Pharmacol Ther       Date:  1981

9.  Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study.

Authors:  Kirsten K Ness; Kevin R Krull; Kendra E Jones; Daniel A Mulrooney; Gregory T Armstrong; Daniel M Green; Wassim Chemaitilly; Webb A Smith; Carmen L Wilson; Charles A Sklar; Kyla Shelton; Deo Kumar Srivastava; Sabeen Ali; Leslie L Robison; Melissa M Hudson
Journal:  J Clin Oncol       Date:  2013-11-18       Impact factor: 44.544

10.  Rethinking schizophrenia in the context of normal neurodevelopment.

Authors:  Vibeke S Catts; Samantha J Fung; Leonora E Long; Dipesh Joshi; Ans Vercammen; Katherine M Allen; Stu G Fillman; Debora A Rothmond; Duncan Sinclair; Yash Tiwari; Shan-Yuan Tsai; Thomas W Weickert; Cynthia Shannon Weickert
Journal:  Front Cell Neurosci       Date:  2013-05-15       Impact factor: 5.505

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  32 in total

1.  Fetal Alcohol Spectrum Disorders: A Case Study.

Authors:  Leila Glass; Sarah N Mattson
Journal:  J Pediatr Neuropsychol       Date:  2017-01-30

Review 2.  Clinical presentation, diagnosis, and management of fetal alcohol spectrum disorder.

Authors:  Jeffrey R Wozniak; Edward P Riley; Michael E Charness
Journal:  Lancet Neurol       Date:  2019-05-31       Impact factor: 44.182

3.  Neural correlates of verbal memory in youth with heavy prenatal alcohol exposure.

Authors:  Lauren A Gross; Eileen M Moore; Jeffrey R Wozniak; Claire D Coles; Julie A Kable; Elizabeth R Sowell; Kenneth L Jones; Edward P Riley; Sarah N Mattson
Journal:  Brain Imaging Behav       Date:  2018-06       Impact factor: 3.978

4.  Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder.

Authors:  Jessie Newville; Carlos Fernando Valenzuela; Lu Li; Lauren L Jantzie; Lee Anna Cunningham
Journal:  Glia       Date:  2017-05-18       Impact factor: 7.452

5.  Alterations in sperm-inherited noncoding RNAs associate with late-term fetal growth restriction induced by preconception paternal alcohol use.

Authors:  Yudhishtar Bedi; Richard C Chang; Rachel Gibbs; Tracy M Clement; Michael C Golding
Journal:  Reprod Toxicol       Date:  2019-04-30       Impact factor: 3.143

Review 6.  The Genetics of Fetal Alcohol Spectrum Disorders.

Authors:  Johann K Eberhart; Scott E Parnell
Journal:  Alcohol Clin Exp Res       Date:  2016-04-28       Impact factor: 3.455

7.  The effect of prenatal substance use and maternal contingent responsiveness on infant affect.

Authors:  Jean Lowe; Fares Qeadan; Lawrence Leeman; Shikhar Shrestha; Julia M Stephen; Ludmila N Bakhireva
Journal:  Early Hum Dev       Date:  2017-09-11       Impact factor: 2.079

8.  Neonatal Ethanol Exposure Causes Behavioral Deficits in Young Mice.

Authors:  Wenhua Xu; Andrew B Hawkey; Hui Li; Lu Dai; Howard H Brim; Jacqueline A Frank; Jia Luo; Susan Barron; Gang Chen
Journal:  Alcohol Clin Exp Res       Date:  2018-02-13       Impact factor: 3.455

Review 9.  Alcohol-Induced Developmental Origins of Adult-Onset Diseases.

Authors:  Emilie R Lunde; Shannon E Washburn; Michael C Golding; Shameena Bake; Rajesh C Miranda; Jayanth Ramadoss
Journal:  Alcohol Clin Exp Res       Date:  2016-06-02       Impact factor: 3.455

10.  Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE): Review of Evidence and Guidelines for Assessment.

Authors:  Lauren R Doyle; Sarah N Mattson
Journal:  Curr Dev Disord Rep       Date:  2015-06-27
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