| Literature DB >> 26538152 |
J Xu1, T J Carrocci, A A Hoskins.
Abstract
Repurposing the "protein-labeling toolkit" for RNA research could be a pragmatic approach for developing new RNA-labeling methods. We have evolved an RNA aptamer that tightly binds benzylguanine (bG), the key ligand for the protein SNAP-tag. The aptamer tightly binds bG fluorophores and can be purified from cellular RNA with bG agarose under native conditions.Entities:
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Year: 2015 PMID： 26538152 PMCID： PMC5020705 DOI： 10.1039/c5cc07605f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222