Literature DB >> 26506572

Health effects of toxicants: Online knowledge support.

Philip Wexler1, Richard Judson2, Sally de Marcellus3, Joop de Knecht3, Eeva Leinala3.   

Abstract

Research in toxicology generates vast quantities of data which reside on the Web and are subsequently appropriated and utilized to support further research. This data includes a broad spectrum of information about chemical, biological and radiological agents which can affect health, the nature of the effects, treatment, regulatory measures, and more. Information is structured in a variety of formats, including traditional databases, portals, prediction models, and decision making support tools. Online resources are created and housed by a variety of institutions, including libraries and government agencies. This paper focuses on three such institutions and the tools they offer to the public: the National Library of Medicine (NLM) and its Toxicology and Environmental Health Information Program, the United States Environmental Protection Agency (EPA), and the Organisation for Economic Co-operation and Development (OECD). Reference is also made to other relevant organizations. Published by Elsevier Inc.

Entities:  

Keywords:  Chemical databases; Computerized information; Databases; Environmental health; Environmental health database; Hazardous chemicals; National Library of Medicine; OECD; Online toxicology information; Online toxicology resources; Toxicity; Toxicoinformatics; Toxicology; Toxicology databases; Toxicology information; US Environmental Protection Agency

Mesh:

Year:  2015        PMID: 26506572      PMCID: PMC4744126          DOI: 10.1016/j.lfs.2015.10.002

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  13 in total

1.  The U.S. National Library of Medicine's Toxicology and Environmental Health Information Program.

Authors:  Philip Wexler
Journal:  Toxicology       Date:  2004-05-20       Impact factor: 4.221

2.  Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

Authors:  Robert Kavlock; Kelly Chandler; Keith Houck; Sid Hunter; Richard Judson; Nicole Kleinstreuer; Thomas Knudsen; Matt Martin; Stephanie Padilla; David Reif; Ann Richard; Daniel Rotroff; Nisha Sipes; David Dix
Journal:  Chem Res Toxicol       Date:  2012-05-15       Impact factor: 3.739

3.  The World Library of Toxicology, Chemical Safety, and Environmental Health (WLT).

Authors:  Philip Wexler; Steven G Gilbert; Nick Thorp; Elaine Faustman; Donna D Breskin
Journal:  Hum Exp Toxicol       Date:  2010-11-11       Impact factor: 2.903

4.  ITER- International Toxicity Estimates for Risk, new TOXNET database.

Authors:  Patricia Tomasulo
Journal:  Med Ref Serv Q       Date:  2005

Review 5.  Chemical structure indexing of toxicity data on the internet: moving toward a flat world.

Authors:  Ann M Richard; Lois Swirsky Gold; Marc C Nicklaus
Journal:  Curr Opin Drug Discov Devel       Date:  2006-05

Review 6.  Resources for global risk assessment: the International Toxicity Estimates for Risk (ITER) and Risk Information Exchange (RiskIE) databases.

Authors:  Andrea Wullenweber; Oliver Kroner; Melissa Kohrman; Andrew Maier; Michael Dourson; Andrew Rak; Philip Wexler; Chuck Tomljanovic
Journal:  Toxicol Appl Pharmacol       Date:  2008-07-02       Impact factor: 4.219

7.  ACToR--Aggregated Computational Toxicology Resource.

Authors:  Richard Judson; Ann Richard; David Dix; Keith Houck; Fathi Elloumi; Matthew Martin; Tommy Cathey; Thomas R Transue; Richard Spencer; Maritja Wolf
Journal:  Toxicol Appl Pharmacol       Date:  2008-07-11       Impact factor: 4.219

8.  LactMed-new NLM database on drugs and lactation.

Authors:  Patricia Tomasulo
Journal:  Med Ref Serv Q       Date:  2007

9.  Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database.

Authors:  Matthew T Martin; Elizabeth Mendez; Daniel G Corum; Richard S Judson; Robert J Kavlock; Daniel M Rotroff; David J Dix
Journal:  Toxicol Sci       Date:  2009-04-10       Impact factor: 4.849

Review 10.  Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System.

Authors:  Richard S Judson; Matthew T Martin; Peter Egeghy; Sumit Gangwal; David M Reif; Parth Kothiya; Maritja Wolf; Tommy Cathey; Thomas Transue; Doris Smith; James Vail; Alicia Frame; Shad Mosher; Elaine A Cohen Hubal; Ann M Richard
Journal:  Int J Mol Sci       Date:  2012-02-09       Impact factor: 6.208

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.