Literature DB >> 26486341

Drug-Loaded Perfluorocarbon Nanodroplets for Ultrasound-Mediated Drug Delivery.

Natalya Rapoport1.   

Abstract

The interaction of nanoparticles with directed energy is a novel application in targeted drug delivery. This chapter focuses on perfluorocarbon nanoemulsions, whose action in drug delivery depends on the ultrasound-triggered phase shift from liquid to gaseous state. These nanoemulsions have great potential for unloading encapsulated drugs at a desired time and location in the body in response to directed ultrasound. In addition, they actively alter their nano-environment for enhancing drug transport through various biological barriers to sites of action, which significantly enhances therapeutic outcome.

Entities:  

Keywords:  Drug delivery; Perfluorocarbon nanodroplet; Ultrasound

Mesh:

Substances:

Year:  2016        PMID: 26486341     DOI: 10.1007/978-3-319-22536-4_13

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  15 in total

Review 1.  Ultrasound-responsive droplets for therapy: A review.

Authors:  H Lea-Banks; M A O'Reilly; K Hynynen
Journal:  J Control Release       Date:  2018-11-29       Impact factor: 9.776

2.  Noninvasive Ultrasonic Drug Uncaging Maps Whole-Brain Functional Networks.

Authors:  Jeffrey B Wang; Muna Aryal; Qian Zhong; Daivik B Vyas; Raag D Airan
Journal:  Neuron       Date:  2018-11-07       Impact factor: 17.173

3.  Novel method for the formation of monodisperse superheated perfluorocarbon nanodroplets as activatable ultrasound contrast agents.

Authors:  C de Gracia Lux; A M Vezeridis; J Lux; A M Armstrong; S R Sirsi; K Hoyt; R F Mattrey
Journal:  RSC Adv       Date:  2017-10-16       Impact factor: 3.361

4.  Increasing Distribution of Drugs Released from In Situ Forming PLGA Implants Using Therapeutic Ultrasound.

Authors:  Chawan Manaspon; Christopher Hernandez; Pinunta Nittayacharn; Selva Jeganathan; Norased Nasongkla; Agata A Exner
Journal:  Ann Biomed Eng       Date:  2017-09-19       Impact factor: 3.934

5.  Polymeric perfluorocarbon nanoemulsions are ultrasound-activated wireless drug infusion catheters.

Authors:  Q Zhong; B C Yoon; M Aryal; J B Wang; T Ilovitsh; M A Baikoghli; N Hosseini-Nassab; A Karthik; R H Cheng; K W Ferrara; R D Airan
Journal:  Biomaterials       Date:  2019-03-20       Impact factor: 12.479

6.  Color-coded perfluorocarbon nanodroplets for multiplexed ultrasound and Photoacoustic imaging.

Authors:  Daniela Y Santiesteban; Kristina A Hallam; Steven K Yarmoska; Stanislav Y Emelianov
Journal:  Nano Res       Date:  2019-01-23       Impact factor: 8.897

7.  PEGylated PLGA-based phase shift nanodroplets combined with focused ultrasound for blood brain barrier opening in rats.

Authors:  Xiang Zhang; Jiangang Hu; Guanjian Zhao; Ning Huang; Ying Tan; Li Pi; Qing Huang; Feng Wang; Zhigang Wang; Zhibiao Wang; Yuan Cheng
Journal:  Oncotarget       Date:  2017-06-13

8.  Theranostic Performance of Acoustic Nanodroplet Vaporization-Generated Bubbles in Tumor Intertissue.

Authors:  Yi-Ju Ho; Chih-Kuang Yeh
Journal:  Theranostics       Date:  2017-04-03       Impact factor: 11.556

Review 9.  Ultrasound-guided drug delivery in cancer.

Authors:  Sayan Mullick Chowdhury; Taehwa Lee; Jürgen K Willmann
Journal:  Ultrasonography       Date:  2017-05-01

10.  Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions.

Authors:  Raag D Airan; Randall A Meyer; Nicholas P K Ellens; Kelly R Rhodes; Keyvan Farahani; Martin G Pomper; Shilpa D Kadam; Jordan J Green
Journal:  Nano Lett       Date:  2017-01-23       Impact factor: 11.189

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