Literature DB >> 264685

Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells.

R E Fournier, F H Ruddle.   

Abstract

In this report, we describe the production and characterization of proliferating hybrid cell populations generated by fusion of murine microcells with intact mouse, Chinese hamster, and human recipient cells. The microcell hybrids so produced contained one to five intact murine chromosomes derived from the microcell donor. these transferred chromosomes were maintained as functioning genetic elements in the hybrid cells. Our results firmly establish subnuclear particle-mediated chromosome transfer as a valid somatic cell genetic tool.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 264685      PMCID： PMC393251          DOI： 10.1073/pnas.74.1.319

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

1.  A RAPID METHOD FOR VIABLE CELL TITRATION AND CLONE PRODUCTION WITH HELA CELLS IN TISSUE CULTURE: THE USE OF X-IRRADIATED CELLS TO SUPPLY CONDITIONING FACTORS.

Authors:  T T Puck; P I Marcus
Journal:  Proc Natl Acad Sci U S A       Date:  1955-07-15       Impact factor: 11.205

2.  Ouabain as a selective agent in the isolation of somatic cell hybrids.

Authors:  R S Kucherlapati; R M Baker; F H Ruddle
Journal:  Cytogenet Cell Genet       Date:  1975

Review 3.  A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels.

Authors:  E A Nichols; F H Ruddle
Journal:  J Histochem Cytochem       Date:  1973-12       Impact factor: 2.479

4.  A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases.

Authors:  J A Tischfield; H P Bernhard; F H Ruddle
Journal:  Anal Biochem       Date:  1973-06       Impact factor: 3.365

5.  Fluorometric properties of the bibenzimidazole derivative Hoechst 33258, a fluorescent probe specific for AT concentration in chromosomal DNA.

Authors:  B Weisblum; E Haenssler
Journal:  Chromosoma       Date:  1974       Impact factor: 4.316

6.  The use of drug-resistant markers to study the hybridization of mouse fibroblasts.

Authors:  J W Littlefield
Journal:  Exp Cell Res       Date:  1966-01       Impact factor: 3.905

7.  Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome.

Authors:  C Kozak; E Nichols; F H Ruddle
Journal:  Somatic Cell Genet       Date:  1975-10

8.  Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase B and peptidase B genes.

Authors:  A S Santachiara; M Nabholz; V Miggiano; A J Darlington; W Bodmer
Journal:  Nature       Date:  1970-07-18       Impact factor: 49.962

9.  Transfer of genetic information by purified metaphase chromosomes.

Authors:  O W McBride; H L Ozer
Journal:  Proc Natl Acad Sci U S A       Date:  1973-04       Impact factor: 11.205

10.  Non-random loss of human markers from man-mouse somatic cell hybrids.

Authors:  R A Norum; B R Migeon
Journal:  Nature       Date:  1974-09-06       Impact factor: 49.962
View more
  79 in total

Review 1.  Microcell-mediated chromosome transfer (MMCT): small cells with huge potential.

Authors:  Aideen M O Doherty; Elizabeth M C Fisher
Journal:  Mamm Genome       Date:  2003-09       Impact factor: 2.957

2.  Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids.

Authors:  B S Glisson; A M Killary; P Merta; W E Ross; J Siciliano; M J Siciliano
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

Review 3.  Artificial chromosome-based transgenes in the study of genome function.

Authors:  Jason D Heaney; Sarah K Bronson
Journal:  Mamm Genome       Date:  2006-08-04       Impact factor: 2.957

Review 4.  Human artificial chromosomes for gene delivery and the development of animal models.

Authors:  Yasuhiro Kazuki; Mitsuo Oshimura
Journal:  Mol Ther       Date:  2011-07-12       Impact factor: 11.454

Review 5.  Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants.

Authors:  L Larizza; V Schirrmacher
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

6.  Introduction of a human X-6 translocation chromosome into a mouse teratocarcinoma: investigation of control of HLA-A, B, C expression.

Authors:  P N Goodfellow; G Banting; J Trowsdale; S Chambers; E Solomon
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

7.  Construction of microcell hybrid clones containing specific mouse chromosomes: application to autosomes 8 and 17.

Authors:  R E Fournier; J A Frelinger
Journal:  Mol Cell Biol       Date:  1982-05       Impact factor: 4.272

8.  Assignment of the gene governing cellular ouabain resistance to Mus musculus chromosome 3 using human/mouse microcell hybrids.

Authors:  C A Kozak; R E Fournier; L A Leinwand; F H Ruddle
Journal:  Biochem Genet       Date:  1979-02       Impact factor: 1.890

9.  A method to generate microcells from human lymphoblasts for use in microcell mediated chromosome transfer.

Authors:  D L Devore-Carter; E Pietrzak; S Kakati
Journal:  In Vitro Cell Dev Biol       Date:  1986-10

Review 10.  A new generation of human artificial chromosomes for functional genomics and gene therapy.

Authors:  Natalay Kouprina; William C Earnshaw; Hiroshi Masumoto; Vladimir Larionov
Journal:  Cell Mol Life Sci       Date:  2012-08-21       Impact factor: 9.261
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.