| Literature DB >> 26467656 |
Yumi Hayashi1, Yasumasa Okamoto2, Koki Takagaki3, Go Okada4, Shigeru Toki5, Takeshi Inoue6, Hajime Tanabe7, Makoto Kobayakawa8, Shigeto Yamawaki9.
Abstract
BACKGROUND: It is known that the onset, progression, and prognosis of major depressive disorder are affected by interactions between a number of factors. This study investigated how childhood abuse, personality, and stress of life events were associated with symptoms of depression in depressed people.Entities:
Mesh:
Year: 2015 PMID: 26467656 PMCID: PMC4604614 DOI: 10.1186/s12888-015-0636-1
Source DB: PubMed Journal: BMC Psychiatry ISSN: 1471-244X Impact factor: 3.630
Fig. 1A structural equation model of the hypothesis in this study. We developed a hypothesis model that in which childhood abuse affected symptoms of depression directly and indirectly through personality and adulthood life events, and in which the personality affected stressful life events
Demographics characteristics of the participants
| Means ± SD or numbers ( | ||
|---|---|---|
| Age | 41.91 ± 11.20 | |
| Gender | Male/Female | 55/58 |
| recurrence of depression | +/- | 59/54 |
| BDI-II | 31.51 ± 9.19 | |
| NEO-FFI | Neuroticism | 53.88 ± 7.86 |
| Extroversion | 39.34 ± 8.77 | |
| Openness to experience | 39.95 ± 9.53 | |
| Agreeableness | 49.66 ± 10.12 | |
| Conscientiousness | 47.55 ± 9.99 | |
| CATS | Neglect | 13.48 ± 10.39 |
| Sexual Abuse | 0.57 ± 1.82 | |
| Punishment | 8.71 ± 4.23 | |
| Emotional Abuse | 5.52 ± 5.33 | |
| LES | Negative | 8.19 ± 6.76 |
| Positive | 1.25 ± 2.40 | |
| Comorbidity | Generalized anxiety disorder | 3 |
| Panic disorder | 6 | |
| Agoraphobia | 10 | |
| Social phobia | 23 | |
| Obsessive-compulsive disorder | 0 | |
| Posttraumatic stress disorder | 0 |
Abbreviations: BDI-II Beck Depression Inventory – 2nd edition, NEO-FFI Neuroticism Extroversion Openness Five Factor Inventory, CATS Child Abuse and Trauma Scale, LES Life Experiences Survey, Negative negative life change score, Positive positive life change score
Fig. 2Results of covariance structure analysis of structural equation model (SEM). These are the results of covaliance structure analysis in the SEM with childhood abuse (CATS), personality (N, E, C of NEO-FFI), adulthood life events (Negative score of LES), and depression symptoms (BDI-II) for 113 patients of major depressive disorder. The allows with continuous lines represent the statistically significant paths, and the dashed lines show the non-significant paths. The numbers on the allows show the standardized path coefficients (minimun −1, maximum 1). Indirect effects indicate the effect mediated by the other valiables. There is direct influence from childhood abuse to severity of depression. There is also indirect effect via personality. Chi-square value: 28.83 (p=.19); CFI=.98, RMSEA=.05: a good fit.indirect effect= .3749, square sums of multiple correlation coefficient=.43. continuous line: p<.05, dashed line: p=not significant. Abbreviations: BDI-II Beck Depression Inventory – 2nd edition, NEO-N Neuroticism of Neuroticism Extroversion Openness Five Factor Inventory, NEO-E Extroversion of Neuroticism Extroversion Openness Five Factor Inventory, NEO-C Conscientiousness of Neuroticism Extroversion Openness Five Factor Inventory, CATS-N Neglect of Child Abuse and Trauma Scale, CATS-S Sexual Abuse of Child Abuse and Trauma Scale, CATS-P Punishment of Child Abuse and Trauma Scale, CATS-E Emotional Abuse of Child Abuse and Trauma Scale, LES-Negative Negative life change score of Life Experiences Survey, CFI Comparative Fit Index, RMSEA Root Mean Square Error of Approximation
Correlation coefficients between BDI-II and each subscale of NEO-FFI, CATS, and LES
| BDI-II | NEO-N | NEO-E | NEO-O | NEO-A | NEO-C | CATS-N | CATS-S | CATS-P | CATS-E | LES-N | LES-P | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BDI-II | ||||||||||||
| NEO-N | .47** | |||||||||||
| NEO-E | -.25** | -.31** | ||||||||||
| NEO-O | -.05 | -.03 | .07 | |||||||||
| NEO-A | -.19* | -.30** | .12 | .15 | ||||||||
| NEO-C | -.30** | -.35** | .28** | .01 | .09 | |||||||
| CATS-N | .28** | .28** | -.06 | .13 | -.16 | -.10 | ||||||
| CATS-S | .15 | .15 | .00 | -.00 | -.06 | -.05 | .45** | |||||
| CATS-P | .29** | .01 | -.03 | -.02 | -.14 | .03 | .42** | .17 | ||||
| CATS-E | .39** | .27* | -.04 | .18 | -.20* | -.16 | .74** | .38** | .48** | |||
| LES-N | .29** | .24* | -.07 | .03 | -.17 | -.14 | .31** | .33** | .07 | .25** | ||
| LES-P | .03 | .06 | .00 | .25** | -.05 | .01 | .27** | .50** | .07 | .17 | .18 |
**p < .01, *p < .05
Abbreviations: BDI-II Beck Depression Inventory – 2nd edition, NEO-N Neuroticism of Neuroticism Extroversion Openness Five Factor Inventory, NEO-E Extroversion of Neuroticism Extroversion Openness Five Factor Inventory, NEO-O Openness to experience of Neuroticism Extroversion Openness Five Factor Inventory, NEO-A Agreeableness of Neuroticism Extroversion Openness Five Factor Inventory, NEO-C Conscientiousness of Neuroticism Extroversion Openness Five Factor Inventory, CATS-N Neglect of Child Abuse and Trauma Scale, CATS-S Sexual Abuse of Child Abuse and Trauma Scale, CATS-P Punishment of Child Abuse and Trauma Scale, CATS-E Emotional Abuse of Child Abuse and Trauma Scale, LES-N Negative life change score of Life Experiences Survey, LES-P Positive life change score of Life Experiences Survey