Literature DB >> 24122075

Sexual and physical abuse in childhood is associated with depression and anxiety over the life course: systematic review and meta-analysis.

Jutta Lindert, Ondine S von Ehrenstein, Rachel Grashow, Gilad Gal, Elmar Braehler, Marc G Weisskopf.   

Abstract

OBJECTIVES: To determine whether depression and anxiety in adulthood are associated with abuse exposure in childhood.
METHODS: A search of PUBMED, EMBASE and PSYCHINFO databases (2002–2012) was supplemented by hand searches of bibliographies of articles and reviews. We included studies contrasting abuse exposure vs. no-abuse exposure before age 16 years to depression and anxiety after age 16 years. Data on sample and exposure and outcome instruments, covariates and odds ratios (ORs) with the respective 95 % confidence intervals (CI) were extracted. Combined ORs and 95 % CI were calculated using random effects models. Heterogeneity was quantified using the I(2) test.
RESULTS: Inclusion criteria were met by 19 studies with 115,579 study participants, for assessing depression (n = 14) and anxiety (n = 13). The combined ORs for depression were 2.04 (95 % CI: 1.65–2.53) for sexual abuse and 1.49 (95 % CI: 1.29–1.72) for physical abuse.The combined ORs for anxiety were 2.52 (95 % CI:2.12–2.98) for sexual abuse and 1.70 (95 % CI: 1.33–2.18)for physical abuse.
CONCLUSIONS: High levels of depression, anxiety and distress are reported in adults exposed to childhood sexual and physical abuse. These findings require increased awareness for the potential needs of adults exposed to child abuse and public health interventions to prevent child abuse.

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Mesh:

Year:  2014        PMID: 24122075     DOI: 10.1007/s00038-013-0519-5

Source DB:  PubMed          Journal:  Int J Public Health        ISSN: 1661-8556            Impact factor:   3.380


  62 in total

1.  Quantifying heterogeneity in a meta-analysis.

Authors:  Julian P T Higgins; Simon G Thompson
Journal:  Stat Med       Date:  2002-06-15       Impact factor: 2.373

2.  Association of childhood adversities with the first onset of mental disorders in Japan: results from the World Mental Health Japan, 2002-2004.

Authors:  Takeo Fujiwara; Norito Kawakami
Journal:  J Psychiatr Res       Date:  2010-08-21       Impact factor: 4.791

3.  Externalizing behavior among adopted boys with preadoptive histories of child sexual abuse.

Authors:  Blace Arthur Nalavany; Scott D Ryan; Jim Hinterlong
Journal:  J Child Sex Abus       Date:  2009-09

4.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire.

Authors:  R L Spitzer; K Kroenke; J B Williams
Journal:  JAMA       Date:  1999-11-10       Impact factor: 56.272

5.  Childhood sexual abuse and adult psychiatric and substance use disorders in women: an epidemiological and cotwin control analysis.

Authors:  K S Kendler; C M Bulik; J Silberg; J M Hettema; J Myers; C A Prescott
Journal:  Arch Gen Psychiatry       Date:  2000-10

6.  Childhood adversity, recent life events and depression in late life.

Authors:  Hannie C Comijs; Aartjan T F Beekman; Filip Smit; Marijke Bremmer; Theo van Tilburg; Dorly J H Deeg
Journal:  J Affect Disord       Date:  2007-02-08       Impact factor: 4.839

7.  Intimate partner violence victimization and perpetration by Puerto Rican women with severe mental illnesses.

Authors:  Susan Hatters Friedman; Sana Loue; Emily L Goldman Heaphy; Nancy Mendez
Journal:  Community Ment Health J       Date:  2009-12-03

8.  Childhood trauma and dissociation in patients with alcohol dependence, drug dependence, or both-A multi-center study.

Authors:  Ingo Schäfer; Willemien Langeland; Johanna Hissbach; Christel Luedecke; Martin D Ohlmeier; Claudia Chodzinski; Ulrich Kemper; Peter Keiper; Dirk Wedekind; Ursula Havemann-Reinecke; Sybille Teunissen; Steffen Weirich; Martin Driessen
Journal:  Drug Alcohol Depend       Date:  2010-01-21       Impact factor: 4.492

9.  Long-term effects of childhood abuse on the quality of life and health of older people: results from the Depression and Early Prevention of Suicide in General Practice Project.

Authors:  Brian Draper; Jon J Pfaff; Jane Pirkis; John Snowdon; Nicola T Lautenschlager; Ian Wilson; Osvaldo P Almeida
Journal:  J Am Geriatr Soc       Date:  2007-11-21       Impact factor: 5.562

Review 10.  Traumatic stress: effects on the brain.

Authors:  J Douglas Bremner
Journal:  Dialogues Clin Neurosci       Date:  2006       Impact factor: 5.986

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  112 in total

1.  Gender Differences in the Association between Adverse Childhood Experiences and Cancer.

Authors:  Héctor E Alcalá; A Janet Tomiyama; Ondine S von Ehrenstein
Journal:  Womens Health Issues       Date:  2017-07-31

2.  Adverse Childhood Experiences, Smoking and Alcohol Use, and Allostatic Load Among People Living with HIV.

Authors:  Maeve Wallace; Erica Felker-Kantor; Aubrey Madkour; Tekeda Ferguson; David Welsh; Patricia Molina; Katherine P Theall
Journal:  AIDS Behav       Date:  2020-06

3.  The development of an instrument to measure global dimensions of maternal care in rhesus macaques (Macaca mulatta).

Authors:  K McCormack; B R Howell; D Guzman; C Villongco; K Pears; H Kim; M R Gunnar; M M Sanchez
Journal:  Am J Primatol       Date:  2014-07-25       Impact factor: 2.371

Review 4.  [Resilience trajectories-examples from longitudinal studies].

Authors:  J Lindert; A Schick; A Reif; R Kalisch; O Tüscher
Journal:  Nervenarzt       Date:  2018-07       Impact factor: 1.214

5.  Child Abuse, Resting Blood Pressure, and Blood Pressure Reactivity to Psychosocial Stress.

Authors:  Holly C Gooding; Carly E Milliren; S Bryn Austin; Margaret A Sheridan; Katie A McLaughlin
Journal:  J Pediatr Psychol       Date:  2015-05-15

Review 6.  The Devastating Clinical Consequences of Child Abuse and Neglect: Increased Disease Vulnerability and Poor Treatment Response in Mood Disorders.

Authors:  Elizabeth T C Lippard; Charles B Nemeroff
Journal:  Am J Psychiatry       Date:  2019-09-20       Impact factor: 18.112

7.  Childhood abuse and suicidal ideation in a cohort of pregnant Peruvian women.

Authors:  Qiu-Yue Zhong; Anne Wells; Marta B Rondon; Michelle A Williams; Yasmin V Barrios; Sixto E Sanchez; Bizu Gelaye
Journal:  Am J Obstet Gynecol       Date:  2016-05-10       Impact factor: 8.661

8.  Health Status and Social Characteristics Among the Uninsured Using a Mental Health Free Clinic.

Authors:  Akiko Kamimura; Noel Gardner; Fattima Ahmed; Maziar M Nourian; Kyl Myers; Lenora M Olson
Journal:  J Behav Health Serv Res       Date:  2018-01       Impact factor: 1.505

9.  Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis.

Authors:  Caitlin E Carey; Arpana Agrawal; Bo Zhang; Emily D Conley; Louisa Degenhardt; Andrew C Heath; Daofeng Li; Michael T Lynskey; Nicholas G Martin; Grant W Montgomery; Ting Wang; Laura J Bierut; Ahmad R Hariri; Elliot C Nelson; Ryan Bogdan
Journal:  J Abnorm Psychol       Date:  2015-11

10.  Parent-Focused Prevention of Child Sexual Abuse.

Authors:  Tamar Mendelson; Elizabeth J Letourneau
Journal:  Prev Sci       Date:  2015-08
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