Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 All about that Amide Bond: The Sixth Chemical Protein Synthesis (CPS) Meeting.

Literature DB >> 26457983

All about that Amide Bond: The Sixth Chemical Protein Synthesis (CPS) Meeting.

Caroline E Weller¹, Champak Chatterjee².

Abstract

Endless potential: The sixth Chemical Protein Synthesis Meeting, held recently in St. Augustine, Florida, showed the potential of peptide and protein chemistry when applied toward understanding and controlling complex biological processes. This report highlights the diverse and cutting-edge protein chemistry presented at the meeting.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2015 PMID： 26457983 PMCID： PMC4749268 DOI： 10.1002/cbic.201500473

Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164

39 in total

1. A miniaturized readout strategy for endogenous histone deacetylase activity.

Authors: Jan Oliver Jost; Alfred Hanswillemenke; Dirk Schwarzer
Journal: Mol Biosyst Date: 2015-07

2. Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability.

Authors: Paul B Lawrence; Yulian Gavrilov; Sam S Matthews; Minnie I Langlois; Dalit Shental-Bechor; Harry M Greenblatt; Brijesh K Pandey; Mason S Smith; Ryan Paxman; Chad D Torgerson; Jacob P Merrell; Cameron C Ritz; Maxim B Prigozhin; Yaakov Levy; Joshua L Price
Journal: J Am Chem Soc Date: 2014-12-04 Impact factor: 15.419

3. Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases.

Authors: Somasekhar Bondalapati; Wissam Mansour; Mark A Nakasone; Suman Kumar Maity; Michael H Glickman; Ashraf Brik
Journal: Chemistry Date: 2015-04-01 Impact factor: 5.236

4. Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins.

Authors: Simon Ng; Edith Lin; Pavel I Kitov; Katrina F Tjhung; Oksana O Gerlits; Lu Deng; Brian Kasper; Amika Sood; Beth M Paschal; Ping Zhang; Chang-Chun Ling; John S Klassen; Christopher J Noren; Lara K Mahal; Robert J Woods; Leighton Coates; Ratmir Derda
Journal: J Am Chem Soc Date: 2015-04-16 Impact factor: 15.419

5. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

Authors: Jingjing Wan; Johnny X Huang; Irina Vetter; Mehdi Mobli; Joshua Lawson; Han-Shen Tae; Nikita Abraham; Blessy Paul; Matthew A Cooper; David J Adams; Richard J Lewis; Paul F Alewood
Journal: J Am Chem Soc Date: 2015-03-03 Impact factor: 15.419

6. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.

Authors: Justin K Murray; Joseph Ligutti; Dong Liu; Anruo Zou; Leszek Poppe; Hongyan Li; Kristin L Andrews; Bryan D Moyer; Stefan I McDonough; Philippe Favreau; Reto Stöcklin; Les P Miranda
Journal: J Med Chem Date: 2015-02-19 Impact factor: 7.446

All about that Amide Bond: The Sixth Chemical Protein Synthesis (CPS) Meeting.

1. A miniaturized readout strategy for endogenous histone deacetylase activity.

2. Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability.

3. Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases.

4. Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins.

5. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

6. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.

7. Synthesis of proteins by native chemical ligation.

8. Spontaneous CO release from Ru(II)(CO)2-protein complexes in aqueous solution, cells, and mice.

9. Genetic code expansion enables live-cell and super-resolution imaging of site-specifically labeled cellular proteins.

10. Chemical tagging and customizing of cellular chromatin states using ultrafast trans-splicing inteins.

1. Advancing the Frontiers of Chemical Protein Synthesis-The 7^th CPS Meeting, Haifa, Israel.