Literature DB >> 26453296

Male hormonal contraception: looking back and moving forward.

M Y Roth1, S T Page1, W J Bremner1.   

Abstract

Despite numerous contraceptive options available to women, approximately half of all pregnancies in the United States and worldwide are unplanned. Women and men support the development of reversible male contraception strategies, but none have been brought to market. Herein we review the physiologic basis for male hormonal contraception, the history of male hormonal contraception development, currents agents in development as well as the potential risks and benefits of male hormonal contraception for men.
© 2015 American Society of Andrology and European Academy of Andrology.

Entities:  

Keywords:  contraception; spermatogenesis; testosterone

Mesh:

Substances:

Year:  2015        PMID: 26453296      PMCID: PMC4718868          DOI: 10.1111/andr.12110

Source DB:  PubMed          Journal:  Andrology        ISSN: 2047-2919            Impact factor:   3.842


  81 in total

1.  Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist.

Authors:  Stephanie T Page; John K Amory; Bradley D Anawalt; Michael S Irwig; Andrew T Brockenbrough; Alvin M Matsumoto; William J Bremner
Journal:  J Clin Endocrinol Metab       Date:  2006-08-29       Impact factor: 5.958

2.  Induced abortion: estimated rates and trends worldwide.

Authors:  Gilda Sedgh; Stanley Henshaw; Susheela Singh; Elisabeth Ahman; Iqbal H Shah
Journal:  Lancet       Date:  2007-10-13       Impact factor: 79.321

3.  Contraceptive failure rates in France: results from a population-based survey.

Authors:  C Moreau; J Trussell; G Rodriguez; N Bajos; J Bouyer
Journal:  Hum Reprod       Date:  2007-06-28       Impact factor: 6.918

4.  Nestorone: a progestin with a unique pharmacological profile.

Authors:  N Kumar; S S Koide; Y Tsong; K Sundaram
Journal:  Steroids       Date:  2000 Oct-Nov       Impact factor: 2.668

5.  Rates of suppression and recovery of human sperm output in testosterone-based hormonal contraceptive regimens.

Authors:  Lam P Ly; Peter Y Liu; David J Handelsman
Journal:  Hum Reprod       Date:  2005-04-28       Impact factor: 6.918

6.  A multicenter contraceptive efficacy study of injectable testosterone undecanoate in healthy Chinese men.

Authors:  Yi-Qun Gu; Xing-Hai Wang; Dwo Xu; Lin Peng; Li-Fa Cheng; Ming-Kong Huang; Zhen-Jia Huang; Gui-Yuan Zhang
Journal:  J Clin Endocrinol Metab       Date:  2003-02       Impact factor: 5.958

Review 7.  Advances in male contraception.

Authors:  Stephanie T Page; John K Amory; William J Bremner
Journal:  Endocr Rev       Date:  2008-04-24       Impact factor: 19.871

8.  A clinical trial of 7 alpha-methyl-19-nortestosterone implants for possible use as a long-acting contraceptive for men.

Authors:  Sigrid von Eckardstein; Gabriela Noe; Vivian Brache; Eberhard Nieschlag; Horacio Croxatto; Francisco Alvarez; Alfred Moo-Young; Irving Sivin; Narender Kumar; Margaret Small; Kalyan Sundaram
Journal:  J Clin Endocrinol Metab       Date:  2003-11       Impact factor: 5.958

9.  Male hormonal contraception: effects of injections of testosterone undecanoate and depot medroxyprogesterone acetate at eight-week intervals in chinese men.

Authors:  Yi-Qun Gu; Jian-Sun Tong; Ding-Zhi Ma; Xing-Hai Wang; Dong Yuan; Wen-Hao Tang; William J Bremner
Journal:  J Clin Endocrinol Metab       Date:  2004-05       Impact factor: 5.958

10.  A new combination of testosterone and nestorone transdermal gels for male hormonal contraception.

Authors:  Niloufar Ilani; Mara Y Roth; John K Amory; Ronald S Swerdloff; Clint Dart; Stephanie T Page; William J Bremner; Regine Sitruk-Ware; Narender Kumar; Diana L Blithe; Christina Wang
Journal:  J Clin Endocrinol Metab       Date:  2012-07-12       Impact factor: 5.958

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  5 in total

1.  Are men ready to use thermal male contraception? Acceptability in two French populations: New fathers and new providers.

Authors:  Marie Amouroux; Roger Mieusset; Raoul Desbriere; Pierre Opinel; Gilles Karsenty; Marine Paci; Sara Fernandes; Blandine Courbiere; Jeanne Perrin
Journal:  PLoS One       Date:  2018-05-29       Impact factor: 3.240

Review 2.  The future of male contraception: a fertile ground.

Authors:  Iyad Khourdaji; Jacqueline Zillioux; Kevin Eisenfrats; Daniel Foley; Ryan Smith
Journal:  Transl Androl Urol       Date:  2018-05

3.  Acceptability of oral dimethandrolone undecanoate in a 28-day placebo-controlled trial of a hormonal male contraceptive prototype.

Authors:  Brian T Nguyen; Maritza T Farrant; Bradley D Anawalt; Fiona Yuen; Arthi Thirumalai; John K Amory; Ronald S Swerdloff; William J Bremner; Peter Y Liu; Diana L Blithe; Stephanie T Page; Christina Wang
Journal:  Contraception       Date:  2020-04-13       Impact factor: 3.375

Review 4.  Male Hormonal Contraception: Where Are We Now?

Authors:  Christina Wang; Mario P R Festin; Ronald S Swerdloff
Journal:  Curr Obstet Gynecol Rep       Date:  2016-01-29

5.  Testis-specific serine kinase protein family in male fertility and as targets for non-hormonal male contraception†.

Authors:  Ana M Salicioni; María G Gervasi; Julian Sosnik; Darya A Tourzani; Saman Nayyab; Diego A Caraballo; Pablo E Visconti
Journal:  Biol Reprod       Date:  2020-08-04       Impact factor: 4.285

  5 in total

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