| Literature DB >> 26449990 |
Nathan A Parks1, Chiara Mazzi2, Evelina Tapia3, Silvia Savazzi2, Monica Fabiani3, Gabriele Gratton3, Diane M Beck3.
Abstract
The posterior parietal cortex (PPC) is a critical node in attentional and saccadic eye movement networks of the cerebral cortex, exerting top-down control over activity in visual cortex. Here, we sought to further elucidate the properties of PPC feedback by providing a time-resolved map of functional connectivity between parietal and occipital cortex using single-pulse TMS to stimulate the left PPC while concurrently recording fast optical imaging data from bilateral occipital cortex. Magnetic stimulation of the PPC induced transient ipsilateral occipital activations (BA 18) 24-48ms post-TMS. Concurrent TMS and fast optical imaging results demonstrate a clear influence of PPC stimulation on activity within human extrastriate visual cortex and further extend this time- and space-resolved method for examining functional connectivity. Published by Elsevier Ltd.Entities:
Keywords: Brain connectivity; Event-related optical signal (EROS); Near-infrared optical imaging; Phosphene; Posterior parietal cortex; Transcranial magnetic stimulation (TMS)
Mesh：
Year: 2015 PMID： 26449990 PMCID： PMC4734125 DOI： 10.1016/j.neuropsychologia.2015.10.002
Source DB: PubMed Journal: Neuropsychologia ISSN： 0028-3932 Impact factor: 3.139