Literature DB >> 26438390

Hybrid stent device of flow-diverting effect and stent-assisted coil embolization formed by fractal structure.

Masahiro Kojima1, Keiko Irie2, Kouhei Masunaga3, Yasuhiko Sakai3, Masahiro Nakajima4, Masaru Takeuchi1, Toshio Fukuda5,6,7, Fumihito Arai1, Makoto Negoro8.   

Abstract

This paper presents a novel hybrid medical stent device. This hybrid stent device formed by fractal mesh structures provides a flow-diverting effect and stent-assisted coil embolization. Flow-diverter stents decrease blood flow into an aneurysm to prevent its rupture. In general, the mesh size of a flow-diverter stent needs to be small enough to prevent blood flow into the aneurysm. Conventional flow-diverter stents are not available for stent-assisted coil embolization, which is an effective method for aneurysm occlusion, because the mesh size is too small to insert a micro-catheter for coil embolization. The proposed hybrid stent device is capable of stent-assisted coil embolization while simultaneously providing a flow-diverting effect. The fractal stent device is composed of mesh structures with fine and rough mesh areas. The rough mesh area can be used to insert a micro-catheter for stent-assisted coil embolization. Flow-diverting effects of two fractal stent designs were composed to three commercially available stent designs. Flow-diverting effects were analyzed using computational fluid dynamics (CFD) analysis and particle image velocimetry (PIV) experiment. Based on the CFD and PIV results, the fractal stent devices reduce the flow velocity inside an aneurism just as much as the commercially available flow-diverting stents while allowing stent-assisted coil embolization.

Entities:  

Keywords:  Aneurysm; Computational fluid dynamics; Flow-diverting effect; Fractal structure; Particle image velocimetry; Stent device

Mesh:

Year:  2015        PMID: 26438390     DOI: 10.1007/s11517-015-1374-8

Source DB:  PubMed          Journal:  Med Biol Eng Comput        ISSN: 0140-0118            Impact factor:   2.602


  13 in total

1.  Endovascular coil occlusion of intracranial aneurysms assisted by a novel self-expandable nitinol microstent (neuroform).

Authors:  H Henkes; A Bose; S Felber; E Miloslavski; E Berg-Dammer; D Kühne
Journal:  Interv Neuroradiol       Date:  2004-10-20       Impact factor: 1.610

2.  The pipeline embolization device for the intracranial treatment of aneurysms trial.

Authors:  P K Nelson; P Lylyk; I Szikora; S G Wetzel; I Wanke; D Fiorella
Journal:  AJNR Am J Neuroradiol       Date:  2010-12-09       Impact factor: 3.825

3.  Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device.

Authors:  I Szikora; Z Berentei; Z Kulcsar; M Marosfoi; Z S Vajda; W Lee; A Berez; P K Nelson
Journal:  AJNR Am J Neuroradiol       Date:  2010-02-11       Impact factor: 3.825

4.  Broad-based intracranial aneurysms: thrombosis induced by stent placement.

Authors:  Ritva Vanninen; Hannu Manninen; Antti Ronkainen
Journal:  AJNR Am J Neuroradiol       Date:  2003-02       Impact factor: 3.825

5.  Flow-diverter stent for the endovascular treatment of intracranial aneurysms: a prospective study in 29 patients with 34 aneurysms.

Authors:  Boris Lubicz; Laurent Collignon; Gaï Raphaeli; Jean-Pierre Pruvo; Michaël Bruneau; Olivier De Witte; Xavier Leclerc
Journal:  Stroke       Date:  2010-08-26       Impact factor: 7.914

6.  Computational fluid dynamics of blood flow in coil-embolized aneurysms: effect of packing density on flow stagnation in an idealized geometry.

Authors:  Tomohiro Otani; Masanori Nakamura; Toshiyuki Fujinaka; Masayuki Hirata; Junko Kuroda; Katsuhiko Shibano; Shigeo Wada
Journal:  Med Biol Eng Comput       Date:  2013-03-26       Impact factor: 2.602

7.  Stent-within-a-stent technique for the treatment of dissecting vertebral artery aneurysms.

Authors:  Bharat Mehta; Tom Burke; Max Kole; Ali Bydon; Donald Seyfried; Ghaus Malik
Journal:  AJNR Am J Neuroradiol       Date:  2003-10       Impact factor: 3.825

8.  Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience.

Authors:  Pedro Lylyk; Carlos Miranda; Rosana Ceratto; Angel Ferrario; Esteban Scrivano; Hugh Ramirez Luna; Aaron L Berez; Quang Tran; Peter K Nelson; David Fiorella
Journal:  Neurosurgery       Date:  2009-04       Impact factor: 4.654

9.  Effects of framing coil shape, orientation, and thickness on intra-aneurysmal flow.

Authors:  Woowon Jeong; Moon Hee Han; Kyehan Rhee
Journal:  Med Biol Eng Comput       Date:  2013-04-08       Impact factor: 2.602

Review 10.  Safety and efficacy of adjunctive balloon remodeling during endovascular treatment of intracranial aneurysms: a literature review.

Authors:  M Shapiro; J Babb; T Becske; P K Nelson
Journal:  AJNR Am J Neuroradiol       Date:  2008-08-21       Impact factor: 3.825

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