| Literature DB >> 26438390 |
Masahiro Kojima1, Keiko Irie2, Kouhei Masunaga3, Yasuhiko Sakai3, Masahiro Nakajima4, Masaru Takeuchi1, Toshio Fukuda5,6,7, Fumihito Arai1, Makoto Negoro8.
Abstract
This paper presents a novel hybrid medical stent device. This hybrid stent device formed by fractal mesh structures provides a flow-diverting effect and stent-assisted coil embolization. Flow-diverter stents decrease blood flow into an aneurysm to prevent its rupture. In general, the mesh size of a flow-diverter stent needs to be small enough to prevent blood flow into the aneurysm. Conventional flow-diverter stents are not available for stent-assisted coil embolization, which is an effective method for aneurysm occlusion, because the mesh size is too small to insert a micro-catheter for coil embolization. The proposed hybrid stent device is capable of stent-assisted coil embolization while simultaneously providing a flow-diverting effect. The fractal stent device is composed of mesh structures with fine and rough mesh areas. The rough mesh area can be used to insert a micro-catheter for stent-assisted coil embolization. Flow-diverting effects of two fractal stent designs were composed to three commercially available stent designs. Flow-diverting effects were analyzed using computational fluid dynamics (CFD) analysis and particle image velocimetry (PIV) experiment. Based on the CFD and PIV results, the fractal stent devices reduce the flow velocity inside an aneurism just as much as the commercially available flow-diverting stents while allowing stent-assisted coil embolization.Entities:
Keywords: Aneurysm; Computational fluid dynamics; Flow-diverting effect; Fractal structure; Particle image velocimetry; Stent device
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Year: 2015 PMID: 26438390 DOI: 10.1007/s11517-015-1374-8
Source DB: PubMed Journal: Med Biol Eng Comput ISSN: 0140-0118 Impact factor: 2.602