Literature DB >> 26435949

Clinico-Microbiological Investigation of Catheter Associated Urinary Tract Infection by Enterococcus faecalis: vanA Genotype.

Kesavaram Padmavathy1, Shabana Praveen2, Radha Madhavan3, Nagarajan Krithika4, Alexander Kiruthiga5.   

Abstract

Prolonged hospitalization and exposure to third generation cephalosporins are reported to facilitate the acquisition and colonization of Vancomycin Resistant Enterococci (VRE). Though VRE is not uncommon in India, urinary tract infection with a vanA genotype is a cause of serious concern as VRE co-exhibit resistance to aminoglycosides. In India, majority of the VRE isolates recovered from hospitalized patients include Enterococcus faecium. We report a case of catheter associated urinary tract infection by an endogenous, multidrug resistant E. faecalis of vanA genotype following prolonged hospitalization, ICU stay, catheterisation and exposure to 3G cephalosporin and metronidazole. The patient responded to linezolid therapy.

Entities:  

Keywords:  High level aminoglycoside resistance (HLAR); Multidrug resistance; Vancomycin resistant Enterococci (VRE)

Year:  2015        PMID: 26435949      PMCID: PMC4576540          DOI: 10.7860/JCDR/2015/13856.6378

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  14 in total

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