| Literature DB >> 26404172 |
Alik S Widge1, Ernesto Licon1, Samuel Zorowitz1, Andrew Corse1, Amanda R Arulpragasam1, Joan A Camprodon1, Cristina Cusin1, Emad N Eskandar1, Thilo Deckersbach1, Darin D Dougherty1.
Abstract
Deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) is a novel therapy for neuropsychiatric disorders. Hypomania is a known complication of VC/VS DBS, but who is at risk is less understood. Factors such as family history, combined with details of DBS programming, might quantify that risk. The authors performed an iterative modeling procedure on a VC/VS DBS patient registry to identify key predictors. Hypomania was less common for men and for patients stimulated on the ventral right contact. It was more common with right monopolar stimulation. These findings may help to establish decision rules to reduce complications of VC/VS DBS.Entities:
Mesh:
Year: 2015 PMID: 26404172 PMCID: PMC5770191 DOI: 10.1176/appi.neuropsych.15040089
Source DB: PubMed Journal: J Neuropsychiatry Clin Neurosci ISSN: 0895-0172 Impact factor: 2.198