Literature DB >> 26399919

From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details.

Clint L Miller1, Milos Pjanic1, Thomas Quertermous1.   

Abstract

Entities:  

Keywords:  alleles; amino acids; binding sites; single nucleotide polymorphism; transcription factors

Mesh：

Year:  2015        PMID： 26399919      PMCID： PMC4594207          DOI： 10.1161/ATVBAHA.115.306366

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


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  5 in total

1.  Prediction of Causal Candidate Genes in Coronary Artery Disease Loci.

Authors:  Ingrid Brænne; Mete Civelek; Baiba Vilne; Antonio Di Narzo; Andrew D Johnson; Yuqi Zhao; Benedikt Reiz; Veronica Codoni; Thomas R Webb; Hassan Foroughi Asl; Stephen E Hamby; Lingyao Zeng; David-Alexandre Trégouët; Ke Hao; Eric J Topol; Eric E Schadt; Xia Yang; Nilesh J Samani; Johan L M Björkegren; Jeanette Erdmann; Heribert Schunkert; Aldons J Lusis
Journal:  Arterioscler Thromb Vasc Biol       Date:  2015-08-20       Impact factor: 8.311

2.  Integrating GWAS and expression data for functional characterization of disease-associated SNPs: an application to follicular lymphoma.

Authors:  Lucia Conde; Paige M Bracci; Rhea Richardson; Stephen B Montgomery; Christine F Skibola
Journal:  Am J Hum Genet       Date:  2012-12-13       Impact factor: 11.025

3.  Large-scale association analysis identifies new risk loci for coronary artery disease.

Authors:  Panos Deloukas; Stavroula Kanoni; Christina Willenborg; Martin Farrall; Themistocles L Assimes; John R Thompson; Erik Ingelsson; Danish Saleheen; Jeanette Erdmann; Benjamin A Goldstein; Kathleen Stirrups; Inke R König; Jean-Baptiste Cazier; Asa Johansson; Alistair S Hall; Jong-Young Lee; Cristen J Willer; John C Chambers; Tõnu Esko; Lasse Folkersen; Anuj Goel; Elin Grundberg; Aki S Havulinna; Weang K Ho; Jemma C Hopewell; Niclas Eriksson; Marcus E Kleber; Kati Kristiansson; Per Lundmark; Leo-Pekka Lyytikäinen; Suzanne Rafelt; Dmitry Shungin; Rona J Strawbridge; Gudmar Thorleifsson; Emmi Tikkanen; Natalie Van Zuydam; Benjamin F Voight; Lindsay L Waite; Weihua Zhang; Andreas Ziegler; Devin Absher; David Altshuler; Anthony J Balmforth; Inês Barroso; Peter S Braund; Christof Burgdorf; Simone Claudi-Boehm; David Cox; Maria Dimitriou; Ron Do; Alex S F Doney; NourEddine El Mokhtari; Per Eriksson; Krista Fischer; Pierre Fontanillas; Anders Franco-Cereceda; Bruna Gigante; Leif Groop; Stefan Gustafsson; Jörg Hager; Göran Hallmans; Bok-Ghee Han; Sarah E Hunt; Hyun M Kang; Thomas Illig; Thorsten Kessler; Joshua W Knowles; Genovefa Kolovou; Johanna Kuusisto; Claudia Langenberg; Cordelia Langford; Karin Leander; Marja-Liisa Lokki; Anders Lundmark; Mark I McCarthy; Christa Meisinger; Olle Melander; Evelin Mihailov; Seraya Maouche; Andrew D Morris; Martina Müller-Nurasyid; Kjell Nikus; John F Peden; N William Rayner; Asif Rasheed; Silke Rosinger; Diana Rubin; Moritz P Rumpf; Arne Schäfer; Mohan Sivananthan; Ci Song; Alexandre F R Stewart; Sian-Tsung Tan; Gudmundur Thorgeirsson; C Ellen van der Schoot; Peter J Wagner; George A Wells; Philipp S Wild; Tsun-Po Yang; Philippe Amouyel; Dominique Arveiler; Hanneke Basart; Michael Boehnke; Eric Boerwinkle; Paolo Brambilla; Francois Cambien; Adrienne L Cupples; Ulf de Faire; Abbas Dehghan; Patrick Diemert; Stephen E Epstein; Alun Evans; Marco M Ferrario; Jean Ferrières; Dominique Gauguier; Alan S Go; Alison H Goodall; Villi Gudnason; Stanley L Hazen; Hilma Holm; Carlos Iribarren; Yangsoo Jang; Mika Kähönen; Frank Kee; Hyo-Soo Kim; Norman Klopp; Wolfgang Koenig; Wolfgang Kratzer; Kari Kuulasmaa; Markku Laakso; Reijo Laaksonen; Ji-Young Lee; Lars Lind; Willem H Ouwehand; Sarah Parish; Jeong E Park; Nancy L Pedersen; Annette Peters; Thomas Quertermous; Daniel J Rader; Veikko Salomaa; Eric Schadt; Svati H Shah; Juha Sinisalo; Klaus Stark; Kari Stefansson; David-Alexandre Trégouët; Jarmo Virtamo; Lars Wallentin; Nicholas Wareham; Martina E Zimmermann; Markku S Nieminen; Christian Hengstenberg; Manjinder S Sandhu; Tomi Pastinen; Ann-Christine Syvänen; G Kees Hovingh; George Dedoussis; Paul W Franks; Terho Lehtimäki; Andres Metspalu; Pierre A Zalloua; Agneta Siegbahn; Stefan Schreiber; Samuli Ripatti; Stefan S Blankenberg; Markus Perola; Robert Clarke; Bernhard O Boehm; Christopher O'Donnell; Muredach P Reilly; Winfried März; Rory Collins; Sekar Kathiresan; Anders Hamsten; Jaspal S Kooner; Unnur Thorsteinsdottir; John Danesh; Colin N A Palmer; Robert Roberts; Hugh Watkins; Heribert Schunkert; Nilesh J Samani
Journal:  Nat Genet       Date:  2012-12-02       Impact factor: 38.330

4.  Single-cell chromatin accessibility reveals principles of regulatory variation.

Authors:  Jason D Buenrostro; Beijing Wu; Ulrike M Litzenburger; Dave Ruff; Michael L Gonzales; Michael P Snyder; Howard Y Chang; William J Greenleaf
Journal:  Nature       Date:  2015-06-17       Impact factor: 49.962

5.  Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.

Authors:  Clint L Miller; Ulrike Haas; Roxanne Diaz; Nicholas J Leeper; Ramendra K Kundu; Bhagat Patlolla; Themistocles L Assimes; Frank J Kaiser; Ljubica Perisic; Ulf Hedin; Lars Maegdefessel; Heribert Schunkert; Jeanette Erdmann; Thomas Quertermous; Georg Sczakiel
Journal:  PLoS Genet       Date:  2014-03-27       Impact factor: 5.917
  5 in total
  7 in total

Review 1.  Cell Death in the Vessel Wall: The Good, the Bad, the Ugly.

Authors:  Katey J Rayner
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-07       Impact factor: 8.311

Review 2.  Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.

Authors:  Kiran Musunuru; Daniel Bernstein; F Sessions Cole; Mustafa K Khokha; Frank S Lee; Shin Lin; Thomas V McDonald; Ivan P Moskowitz; Thomas Quertermous; Vijay G Sankaran; David A Schwartz; Edwin K Silverman; Xiaobo Zhou; Ahmed A K Hasan; Xiao-Zhong James Luo
Journal:  Circ Genom Precis Med       Date:  2018-04

Review 3.  Genetics and Genomics of Coronary Artery Disease.

Authors:  Milos Pjanic; Clint L Miller; Robert Wirka; Juyong B Kim; Daniel M DiRenzo; Thomas Quertermous
Journal:  Curr Cardiol Rep       Date:  2016-10       Impact factor: 2.931

4.  The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.

Authors:  Suowen Xu; Yanni Xu; Peng Liu; Shuya Zhang; Huan Liu; Spencer Slavin; Sandeep Kumar; Marina Koroleva; Jinque Luo; Xiaoqian Wu; Arshad Rahman; Jaroslav Pelisek; Hanjoong Jo; Shuyi Si; Clint L Miller; Zheng Gen Jin
Journal:  Eur Heart J       Date:  2019-08-01       Impact factor: 35.855

5.  Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets.

Authors:  Harri Lempiäinen; Ingrid Brænne; Tom Michoel; Vinicius Tragante; Baiba Vilne; Tom R Webb; Theodosios Kyriakou; Johannes Eichner; Lingyao Zeng; Christina Willenborg; Oscar Franzen; Arno Ruusalepp; Anuj Goel; Sander W van der Laan; Claudia Biegert; Stephen Hamby; Husain A Talukdar; Hassan Foroughi Asl; Gerard Pasterkamp; Hugh Watkins; Nilesh J Samani; Timo Wittenberger; Jeanette Erdmann; Heribert Schunkert; Folkert W Asselbergs; Johan L M Björkegren
Journal:  Sci Rep       Date:  2018-02-21       Impact factor: 4.379

6.  Lipid metabolism patterns and relevant clinical and molecular features of coronary artery disease patients: an integrated bioinformatic analysis.

Authors:  Yanhui Liao; Zhenzhen Dong; Hanhui Liao; Yang Chen; Longlong Hu; Zuozhong Yu; Yi Xia; Yuanbin Zhao; Kunpeng Fan; Jingwen Ding; Xiongda Yao; Tianhua Deng; Renqiang Yang
Journal:  Lipids Health Dis       Date:  2022-09-10       Impact factor: 4.315

7.  Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque.

Authors:  Paul Cheng; Robert C Wirka; Juyong Brian Kim; Hyun-Jung Kim; Trieu Nguyen; Ramendra Kundu; Quanyi Zhao; Disha Sharma; Albert Pedroza; Manabu Nagao; Dharini Iyer; Michael P Fischbein; Thomas Quertermous
Journal:  Nat Cardiovasc Res       Date:  2022-04-13
  7 in total

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