Literature DB >> 26396906

Crystal structure of 10-benzyl-9-(3,4-di-meth-oxy-phen-yl)-3,3,6,6-tetra-methyl-3,4,6,7,9,10-hexa-hydro-acridine-1,8(2H,5H)-dione.

N Sureshbabu1, V Sughanya1.   

Abstract

In the acridinedione moiety of the title compound, C32H37NO4, the central di-hydro-pyridine ring adopts a flattened-boat conformation, with the N atom and the methine C atom displaced from the mean plane of the other four atoms by 0.0513 (14) and 0.1828 (18) Å, respectively. The two cyclo-hexenone rings adopt envelope conformations, with the tetra-subsituted C atoms as the flap atoms. The 3,4-di-meth-oxy--benzene and benzyl rings are almost normal to the di-hydro-pyridine mean plane, with dihedral angles of 89.47 (9) and 82.90 (11)°, respectively. In the crystal, mol-ecules are linked via a pair of C-H⋯O hydrogen bonds, forming inversion dimers, which are, in turn, linked by C-H⋯O hydrogen bonds, forming slabs lying parallel to (001).

Entities:  

Keywords:  acridinedione; benzyl­amine; crystal structure; dimedone

Year:  2015        PMID: 26396906      PMCID: PMC4555413          DOI: 10.1107/S2056989015014966

Source DB:  PubMed          Journal:  Acta Crystallogr E Crystallogr Commun


  8 in total

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Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

2.  Screening of unsubstituted cyclic compounds as inhibitors of monoamine oxidases.

Authors:  U Thull; B Testa
Journal:  Biochem Pharmacol       Date:  1994-06-15       Impact factor: 5.858

Review 3.  Genetic effects of acridine compounds.

Authors:  A Nasim; T Brychcy
Journal:  Mutat Res       Date:  1979-12       Impact factor: 2.433

4.  9-(5-Bromo-2-hy-droxy-phen-yl)-10-(2-hy-droxy-prop-yl)-3,3,6,6-tetra-methyl-1,2,3,4,5,6,7,8,9,10-deca-hydro-acridine-1,8-dione.

Authors:  Ali N Khalilov; Antar A Abdelhamid; Atash V Gurbanov; Seik Weng Ng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-04-16

5.  10-(2-Hy-droxy-eth-yl)-9-(2-hy-droxy-phen-yl)-3,3,6,6-tetra-methyl-1,2,3,4,5,6,7,8,9,10-deca-hydro-acridine-1,8-dione.

Authors:  Antar A Abdelhamid; Shaaban K Mohamed; Ali N Khalilov; Atash V Gurbanov; Seik Weng Ng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-02-26

6.  9-(4-Fluoro-phen-yl)-3,3,6,6-tetra-methyl-10-p-tolyl-1,2,3,4,5,6,7,8,9,10-deca-hydroacridine-1,8-dione.

Authors:  Ziqiang Tang; Changning Liu; Shanshan Wu; Wenjuan Hao
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-08-30

7.  10-Benzyl-9-(4-eth-oxy-phen-yl)-3,3,6,6-tetra-methyl-3,4,6,7,9,10-hexa-hydro-acridine-1,8(2H,5H)-dione.

Authors:  V Sughanya; N Sureshbabu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-08-23

8.  9-(3-Bromo-5-chloro-2-hy-droxy-phen-yl)-10-(2-hy-droxy-eth-yl)-3,6-diphenyl-3,4,9,10-tetra-hydro-acridine-1,8(2H,5H)-dione.

Authors:  Mehmet Akkurt; Shaaban K Mohamed; Antar A Abdelhamid; Abdel-Aal M Gaber; Mustafa R Albayati
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-05-17
  8 in total
  1 in total

1.  Crystal structure, Hirshfeld surface and frontier mol-ecular orbital analysis of 10-benzyl-9-(4-hydroxy-3-meth-oxy-phen-yl)-3,3,6,6-tetra-methyl-3,4,6,7,9,10-hexa-hydro-acridine-1,8(2H,5H)-dione.

Authors:  V Sughanya; B Loganathan; D Praveenkumar; J Ayyappan; M L Sundararajan; A Prabhakaran; A Dhandapani; N Suresh Babu
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2022-07-14
  1 in total

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