Sara Ortiz-Toquero1,2,3, Sofia Perez3, Guadalupe Rodriguez1,2,3, Victoria de Juan1,2,3, Agustin Mayo-Iscar4, Raul Martin5,6,7,8. 1. Departamento de Física Teórica, Atómica y Óptica, Universidad de Valladolid, Paseo de Belén, 7 - Campus Miguel Delibes, 47011, Valladolid, Spain. 2. Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Paseo de Belén, 17 - Campus Miguel Delibes, 47011, Valladolid, Spain. 3. Optometry Research Group, IOBA Eye Institute, School of Optometry, University of Valladolid, Valladolid, Spain. 4. Departamento de Estadística e Investigación Operativa e IMUVA, Universidad de Valladolid, Paseo de Belén, 7 - Campus Miguel Delibes, 47011, Valladolid, Spain. 5. Departamento de Física Teórica, Atómica y Óptica, Universidad de Valladolid, Paseo de Belén, 7 - Campus Miguel Delibes, 47011, Valladolid, Spain. raul@ioba.med.uva.es. 6. Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Paseo de Belén, 17 - Campus Miguel Delibes, 47011, Valladolid, Spain. raul@ioba.med.uva.es. 7. Optometry Research Group, IOBA Eye Institute, School of Optometry, University of Valladolid, Valladolid, Spain. raul@ioba.med.uva.es. 8. Departamento de Estadística e Investigación Operativa e IMUVA, Universidad de Valladolid, Paseo de Belén, 7 - Campus Miguel Delibes, 47011, Valladolid, Spain. raul@ioba.med.uva.es.
Abstract
PURPOSE: The aim of this study was to assess the impact of refractive correction [spectacles vs rigid gas-permeable contact lenses (RGP CLs)] on the vision-related quality of life (VR-QoL) obtained with the standardized questionnaire, NEI-VFQ-25, in keratoconus patients compared with healthy myopic subjects. METHODS: The Spanish version of NEI-VFQ-25 was administered two consecutive times to 25 keratoconus patients (RGP CL wearers) and 25 healthy myopic subjects (RGP and soft CL wearers). The first time was to assess the VR-QoL for spectacle wearing, such as those for refractive correction, and the second time was for CL wearing. RESULTS: Keratoconus patients showed a lower VR-QoL impairment (P < 0.01) than healthy subjects in the total and all subscale score of NEI-VFQ-25 related to wearing spectacles. With CL correction, keratoconus patients showed a VR-QoL improvement with statistically significant differences (P < 0.04) in only four subscales, including distance activities, mental health, color vision and peripheral vision, compared with healthy subjects. In the keratoconus group, compared to spectacle use, CL wear improved the VR-QoL score (P = 0.01) and all subscales except for ocular pain (P < 0.01) and mental health (P = 0.25). CONCLUSIONS: The use of the NEI-VFQ-25 to explore the difference in the VR-QoL between healthy subjects and patients with keratoconus provides further evidence of improved VR-QoL with RGP CL wear compared with spectacles in keratoconus patients. RGP CL management in keratoconus patients could minimize the impact of the disease on the patient's well-being.
PURPOSE: The aim of this study was to assess the impact of refractive correction [spectacles vs rigid gas-permeable contact lenses (RGP CLs)] on the vision-related quality of life (VR-QoL) obtained with the standardized questionnaire, NEI-VFQ-25, in keratoconuspatients compared with healthy myopic subjects. METHODS: The Spanish version of NEI-VFQ-25 was administered two consecutive times to 25 keratoconuspatients (RGP CL wearers) and 25 healthy myopic subjects (RGP and soft CL wearers). The first time was to assess the VR-QoL for spectacle wearing, such as those for refractive correction, and the second time was for CL wearing. RESULTS:Keratoconuspatients showed a lower VR-QoL impairment (P < 0.01) than healthy subjects in the total and all subscale score of NEI-VFQ-25 related to wearing spectacles. With CL correction, keratoconuspatients showed a VR-QoL improvement with statistically significant differences (P < 0.04) in only four subscales, including distance activities, mental health, color vision and peripheral vision, compared with healthy subjects. In the keratoconus group, compared to spectacle use, CL wear improved the VR-QoL score (P = 0.01) and all subscales except for ocular pain (P < 0.01) and mental health (P = 0.25). CONCLUSIONS: The use of the NEI-VFQ-25 to explore the difference in the VR-QoL between healthy subjects and patients with keratoconus provides further evidence of improved VR-QoL with RGP CL wear compared with spectacles in keratoconuspatients. RGP CL management in keratoconuspatients could minimize the impact of the disease on the patient's well-being.
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