| Literature DB >> 26334765 |
Sarah Spencer1,2, Jessie Chung1,2, Mark Thompson1, Pedro A Piedra3,4, Alan Jewell3, Vasanthi Avadhanula3, Minghua Mei3, Michael L Jackson5, Jennifer Meece6, Maria Sundaram6, Edward A Belongia6, Rachel Cross7, Emileigh Johnson7, Arlene Bullotta8, Charles Rinaldo8, Manjusha Gaglani9, Kempapura Murthy9, Lydia Clipper9, LaShondra Berman1, Brendan Flannery1.
Abstract
We evaluated the cycle threshold (CT) values of 1,160 influenza A positive and 806 influenza B positive specimens from two seasons of the US Flu VE Network to identify factors associated with CT values. Low CT values (high genomic load) were associated with shorter intervals between illness onset and specimen collection, young age (ages 3-8 years old), and self-rated illness severity for both influenza A and B. Low CT values were also associated with reported fever/feverishness and age ≥65 years for influenza A.Entities:
Keywords: Influenza; RT-PCR; cycle threshold value
Mesh：
Year: 2015 PMID： 26334765 DOI： 10.1002/jmv.24373
Source DB: PubMed Journal: J Med Virol ISSN： 0146-6615 Impact factor: 2.327