Tan To Cheung1, Ronnie T P Poon2, Wing Chiu Dai2, Kenneth S H Chok2, See Ching Chan2, Chung Mau Lo2. 1. Department of Surgery, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China. tantocheung@hotmail.com. 2. Department of Surgery, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China.
Abstract
INTRODUCTION: Laparoscopic left lateral sectionectomy has been proven to be a safe and effective treatment for liver lesions. However, most of the literatures only reported this treatment method on benign lesion or colorectal metastases. The data on long-term outcome of laparoscopic left lateral section resection in patients with HCC and cirrhosis are still limited. The aim of this study is to analyze the survival outcome of laparoscopic left lateral sectionectomy when compared to open approach in patients with HCCs. METHOD: Between January 2004 and September 2014, 967 patients had primary HCC with hepatectomy performed. Twenty-four patients had undergone pure laparoscopic left lateral sectionectomy for hepatocellular carcinoma (HCC). Twenty-nine patients with case-matched tumor characteristics and liver functions but received open left lateral sectionectomy for HCC were included for comparison. RESULTS: Comparing laparoscopic group to open resection group, the median operation time was 190.5 versus 195 min (P = 0.734); the median blood loss was 100 versus 300 ml (P < 0.001). Hospital stay was 5 days in laparoscopic group versus 6 days in the open group (P = 0.057). There was no difference between the two groups in terms of complications (P = 0.495). The median survival in laparoscopic group was >115 months versus >125 months in the open group (P = 0.853). CONCLUSION: Laparoscopic left lateral sectionectomy for HCC is a safe and simple procedure associated with less blood loss. The survival outcome is comparable with conventional open approach. It is becoming a more favorable treatment option even for patients with HCC and cirrhosis.
INTRODUCTION: Laparoscopic left lateral sectionectomy has been proven to be a safe and effective treatment for liver lesions. However, most of the literatures only reported this treatment method on benign lesion or colorectal metastases. The data on long-term outcome of laparoscopic left lateral section resection in patients with HCC and cirrhosis are still limited. The aim of this study is to analyze the survival outcome of laparoscopic left lateral sectionectomy when compared to open approach in patients with HCCs. METHOD: Between January 2004 and September 2014, 967 patients had primary HCC with hepatectomy performed. Twenty-four patients had undergone pure laparoscopic left lateral sectionectomy for hepatocellular carcinoma (HCC). Twenty-nine patients with case-matched tumor characteristics and liver functions but received open left lateral sectionectomy for HCC were included for comparison. RESULTS: Comparing laparoscopic group to open resection group, the median operation time was 190.5 versus 195 min (P = 0.734); the median blood loss was 100 versus 300 ml (P < 0.001). Hospital stay was 5 days in laparoscopic group versus 6 days in the open group (P = 0.057). There was no difference between the two groups in terms of complications (P = 0.495). The median survival in laparoscopic group was >115 months versus >125 months in the open group (P = 0.853). CONCLUSION: Laparoscopic left lateral sectionectomy for HCC is a safe and simple procedure associated with less blood loss. The survival outcome is comparable with conventional open approach. It is becoming a more favorable treatment option even for patients with HCC and cirrhosis.
Authors: Tan To Cheung; Ronnie T P Poon; Wai Key Yuen; Kenneth S H Chok; Simon H Y Tsang; Thomas Yau; See Ching Chan; Chung Mau Lo Journal: ANZ J Surg Date: 2012-10-04 Impact factor: 1.872
Authors: Tan To Cheung; Chi Lai Ho; Chung Mau Lo; Sirong Chen; See Ching Chan; Kenneth S H Chok; James Y Fung; Albert Chi Yan Chan; William Sharr; Thomas Yau; Ronnie T P Poon; Sheung Tat Fan Journal: J Nucl Med Date: 2013-01-15 Impact factor: 10.057
Authors: Tan To Cheung; Ho-Seong Han; Wong Hoi She; Kuo-Hsin Chen; Pierce K H Chow; Boon Koon Yoong; Kit Fai Lee; Shoji Kubo; Chung Ngai Tang; Go Wakabayashi Journal: Liver Cancer Date: 2017-12-09 Impact factor: 11.740
Authors: Christian Benzing; Felix Krenzien; Georgi Atanasov; Daniel Seehofer; Robert Sucher; Ricardo Zorron; Johann Pratschke; Moritz Schmelzle Journal: GMS Interdiscip Plast Reconstr Surg DGPW Date: 2015-12-15