Tomoko Takamura1, Yoriko Horiguchi2, Masahiko Kanna1, Hirooki Matsushita1, Yuta Sudo1, Shinnosuke Kikuchi1, Tomohiro Ueda3, Ryo Sasaki3, Yukiko Morita1. 1. Department of Cardiology, National Hospital Organization Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku, Sagamihara City, Kanagawa, 252-0392, Japan. 2. Department of Cardiology, National Hospital Organization Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku, Sagamihara City, Kanagawa, 252-0392, Japan. dzq04361@nifty.com. 3. Department of Radiology, National Hospital Organization Sagamihara National Hospital, Kanagawa, Japan.
Abstract
OBJECTIVE: The purpose of this study is to evaluate whether prone myocardial perfusion single-photon emission computed tomography (MPS) with thallium-201 acquired through a variable-focus collimator (IQ-SPECT) can correct for soft-tissue attenuation. METHODS: Thirty-nine patients underwent thallium-201 stress MPS with IQ-SPECT. Delayed images acquired with the patients in the prone position were compared with delayed images obtained with the patients in the supine position with computed tomography-derived attenuation correction (CTAC) (S-CTAC images) or without CTAC (S-NCTAC images). Quantitative tracer uptake (QTU) and semi-quantitative defect scores were determined for the 17 standard myocardial segments. Segments were categorized into anterior-anteroseptal, lateral, inferior, and apex, and areas with defect decision were determined by using the defect scores. RESULTS: Image quality in the prone images was similar to that of S-NCTAC and S-CTAC images. In male patients, QTU in prone images was equivalent to that in S-CTAC images in the anterior-anteroseptal area, but was significantly lower than that in S-CTAC images in the inferior area. In female patients, QTU in prone images was similar to that in S-CTAC images in the anterior-anteroseptal, lateral, and inferior areas. In male and in female patients, QTU in the apex was significantly greater in the prone images than that in the S-CTAC images. In the combined male and female patient group, the defect decision for prone images was similar to that for S-CTAC images in the anterior-anteroseptal, lateral, and inferior areas. Apical defects were observed more frequently in S-CTAC images than in prone or S-NCTAC images. CONCLUSIONS: Fewer artificial defects were observed in the apex of images acquired by prone imaging than by S-CTAC imaging. Prone images improved attenuation and had similar defect decision as S-CTAC images in the anterior-anteroseptal, lateral, and inferior areas.
OBJECTIVE: The purpose of this study is to evaluate whether prone myocardial perfusion single-photon emission computed tomography (MPS) with thallium-201 acquired through a variable-focus collimator (IQ-SPECT) can correct for soft-tissue attenuation. METHODS: Thirty-nine patients underwent thallium-201 stress MPS with IQ-SPECT. Delayed images acquired with the patients in the prone position were compared with delayed images obtained with the patients in the supine position with computed tomography-derived attenuation correction (CTAC) (S-CTAC images) or without CTAC (S-NCTAC images). Quantitative tracer uptake (QTU) and semi-quantitative defect scores were determined for the 17 standard myocardial segments. Segments were categorized into anterior-anteroseptal, lateral, inferior, and apex, and areas with defect decision were determined by using the defect scores. RESULTS: Image quality in the prone images was similar to that of S-NCTAC and S-CTAC images. In male patients, QTU in prone images was equivalent to that in S-CTAC images in the anterior-anteroseptal area, but was significantly lower than that in S-CTAC images in the inferior area. In female patients, QTU in prone images was similar to that in S-CTAC images in the anterior-anteroseptal, lateral, and inferior areas. In male and in female patients, QTU in the apex was significantly greater in the prone images than that in the S-CTAC images. In the combined male and female patient group, the defect decision for prone images was similar to that for S-CTAC images in the anterior-anteroseptal, lateral, and inferior areas. Apical defects were observed more frequently in S-CTAC images than in prone or S-NCTAC images. CONCLUSIONS: Fewer artificial defects were observed in the apex of images acquired by prone imaging than by S-CTAC imaging. Prone images improved attenuation and had similar defect decision as S-CTAC images in the anterior-anteroseptal, lateral, and inferior areas.
Authors: Brian G Abbott; James A Case; Sharmila Dorbala; Andrew J Einstein; James R Galt; Robert Pagnanelli; Renée P Bullock-Palmer; Prem Soman; R Glenn Wells Journal: J Nucl Cardiol Date: 2018-10 Impact factor: 5.952
Authors: Vicente Taasan; Anita Wokhlu; Michael V Taasan; Raman S Dusaj; Ajay Mehta; Steven Kraft; David Winchester; David Wymer Journal: J Nucl Cardiol Date: 2015-12-30 Impact factor: 5.952