Literature DB >> 26295011

Health Literate Organizations: Are Clinical Trial Sites Equipped to Recruit Minority and Limited Health Literacy Patients?

Jennifer Livaudais-Toman1, Nancy J Burke1, Anna Napoles1, Celia P Kaplan1.   

Abstract

BACKGROUND: Racial/ethnic minority patients are less likely than non-Latino white patients to participate in cancer clinical trials. A key barrier to participation is limited health literacy which is more common among minorities. At the organizational level, it is important that clinical trials sites become better equipped to recruit minority patients by expanding their organizational health literacy including language competency and outreach efforts. We explored the characteristics of clinical trial sites that are associated with these health literate behaviors.
METHODS: We identified 353 breast clinical trials recruiting participants in 2006 from four states (California, Florida, Illinois, and New York) through the National Cancer Institute Physician Data Query system. From October 2008 to November 2009, we contacted one research team member (RTM) from each site for a telephone survey to assess the site's health literate characteristics.
RESULTS: Of 233 RTMs who responded, 93% were female and 89% were US-born. Overall, 48% of sites offered supplementary trial information, 80% offered materials to assist with patient navigation and 45% reported outreach efforts. Lower percentages offered information in other languages while 65% offered professional interpretation services. Sites with >10% limited English proficiency (LEP) patients were more likely than their counterparts to offer consent forms (OR=3.13, 1.36-7.19) and supplementary information about trials in other languages (OR=2.52, 1.15-5.52). Sites with diverse patient populations (>10% Latino) were also more likely than less diverse sites to engage in outreach (OR=1.97, 1.07-3.60), to offer consent forms (OR=2.72, 1.38-5.36), supplementary information about trials (OR=2.58, 1.24-5.36), and materials to improve patient navigation (OR=2.50, 1.22-5.13) in other languages.
CONCLUSIONS: Efforts to recruit diverse participants were limited. Practice type and diversity of patient population were associated with sites' efforts to accommodate these characteristics, suggesting that sites were responsive to the needs of their patients when diversity was prevalent.

Entities:  

Keywords:  Cultural Competency; Medicine; Organizational Development; Public Health Sciences

Year:  2014        PMID: 26295011      PMCID: PMC4540367     

Source DB:  PubMed          Journal:  J Health Dispar Res Pract        ISSN: 2166-5222


  23 in total

Review 1.  Adequacy of reporting race/ethnicity in clinical trials in areas of health disparities.

Authors:  Giselle Corbie-Smith; Diane Marie M St George; Sandra Moody-Ayers; David F Ransohoff
Journal:  J Clin Epidemiol       Date:  2003-05       Impact factor: 6.437

Review 2.  Diffusion and adoption of state-of-the-art therapy.

Authors:  L Ford; A D Kaluzny; E Sondik
Journal:  Semin Oncol       Date:  1990-08       Impact factor: 4.929

3.  Provider roles in the recruitment of underrepresented populations to cancer clinical trials.

Authors:  Mollie W Howerton; M Chris Gibbons; Charles R Baffi; Tiffany L Gary; Gabriel Y Lai; Shari Bolen; Jon Tilburt; Teerath Peter Tanpitukpongse; Renee F Wilson; Neil R Powe; Eric B Bass; Jean G Ford
Journal:  Cancer       Date:  2007-02-01       Impact factor: 6.860

Review 4.  The need for more research on language barriers in health care: a proposed research agenda.

Authors:  Elizabeth Jacobs; Alice H M Chen; Leah S Karliner; Niels Agger-Gupta; Sunita Mutha
Journal:  Milbank Q       Date:  2006       Impact factor: 4.911

5.  Representation of Asian Americans in clinical cancer trials.

Authors:  G A Alexander; K C Chu; R C Ho
Journal:  Ann Epidemiol       Date:  2000-11       Impact factor: 3.797

Review 6.  Health literacy and cancer communication.

Authors:  Terry C Davis; Mark V Williams; Estela Marin; Ruth M Parker; Jonathan Glass
Journal:  CA Cancer J Clin       Date:  2002 May-Jun       Impact factor: 508.702

Review 7.  The impact of medical interpreter services on the quality of health care: a systematic review.

Authors:  Glenn Flores
Journal:  Med Care Res Rev       Date:  2005-06       Impact factor: 3.929

8.  Participation in cancer clinical trials: race-, sex-, and age-based disparities.

Authors:  Vivek H Murthy; Harlan M Krumholz; Cary P Gross
Journal:  JAMA       Date:  2004-06-09       Impact factor: 56.272

Review 9.  Do professional interpreters improve clinical care for patients with limited English proficiency? A systematic review of the literature.

Authors:  Leah S Karliner; Elizabeth A Jacobs; Alice Hm Chen; Sunita Mutha
Journal:  Health Serv Res       Date:  2007-04       Impact factor: 3.402

10.  Representation of African-Americans, Hispanics, and whites in National Cancer Institute cancer treatment trials.

Authors:  H A Tejeda; S B Green; E L Trimble; L Ford; J L High; R S Ungerleider; M A Friedman; O W Brawley
Journal:  J Natl Cancer Inst       Date:  1996-06-19       Impact factor: 13.506

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  11 in total

1.  A paradigm for understanding trust and mistrust in medical research: The Community VOICES study.

Authors:  M Smirnoff; I Wilets; D F Ragin; R Adams; J Holohan; R Rhodes; G Winkel; E M Ricci; C Clesca; L D Richardson
Journal:  AJOB Empir Bioeth       Date:  2018-02-16

2.  Who's included? The role of the Clinical Research Nurse in enabling research participation for under-represented and under-served groups.

Authors:  Kelly Beer; Melanie Gentgall; Nicola Templeton; Claire Whitehouse; Nicola Straiton
Journal:  J Res Nurs       Date:  2022-04-01

3.  Health Literacy and Use and Trust in Health Information.

Authors:  Xuewei Chen; Jennifer L Hay; Erika A Waters; Marc T Kiviniemi; Caitlin Biddle; Elizabeth Schofield; Yuelin Li; Kimberly Kaphingst; Heather Orom
Journal:  J Health Commun       Date:  2018-08-30

4.  Engaging limited English proficient and ethnically diverse low-income women in health research: A randomized trial of a patient navigator intervention.

Authors:  Alyssa Nickell; Susan L Stewart; Nancy J Burke; Claudia Guerra; Elly Cohen; Catherine Lawlor; Susan Colen; Janice Cheng; Galen Joseph
Journal:  Patient Educ Couns       Date:  2019-02-11

5.  Positive attitudes toward clinical trials among military veterans leaves unanswered questions about poor trial accrual.

Authors:  Grace Clarke Hillyer; Yeun-Hee Anna Park; Ta-Chueh Hsu Rosenberg; Prabhjot Mundi; Imtiaz Patel; Susan E Bates
Journal:  Semin Oncol       Date:  2021-05-03       Impact factor: 4.929

Review 6.  Applying a Conceptual Framework to Maximize the Participation of Diverse Populations in Cancer Clinical Trials.

Authors:  A Napoles; E Cook; T Ginossar; K D Knight; M E Ford
Journal:  Adv Cancer Res       Date:  2016-10-05       Impact factor: 5.767

7.  The Feasibility of Health Trainer Improved Patient Self-Management in Patients with Low Health Literacy and Poorly Controlled Diabetes: A Pilot Randomised Controlled Trial.

Authors:  Joanne Protheroe; Trishna Rathod; Bernadette Bartlam; Gillian Rowlands; Gerry Richardson; David Reeves
Journal:  J Diabetes Res       Date:  2016-10-19       Impact factor: 4.011

Review 8.  Health Literacy and Cardiovascular Disease: Fundamental Relevance to Primary and Secondary Prevention: A Scientific Statement From the American Heart Association.

Authors:  Jared W Magnani; Mahasin S Mujahid; Herbert D Aronow; Crystal W Cené; Victoria Vaughan Dickson; Edward Havranek; Lewis B Morgenstern; Michael K Paasche-Orlow; Amy Pollak; Joshua Z Willey
Journal:  Circulation       Date:  2018-06-04       Impact factor: 29.690

9.  A Web-Based Intervention to Increase Smokers' Intentions to Participate in a Cessation Study Offered at the Point of Lung Screening: Factorial Randomized Trial.

Authors:  Jordan M Neil; Yuchiao Chang; Brett Goshe; Nancy Rigotti; Irina Gonzalez; Saif Hawari; Lauren Ballini; Jennifer S Haas; Caylin Marotta; Amy Wint; Kim Harris; Sydney Crute; Efren Flores; Elyse R Park
Journal:  JMIR Form Res       Date:  2021-06-30

10.  Health Literacy Within a Diverse Community-Based Cohort: The Multi-Ethnic Study of Atherosclerosis.

Authors:  Madison D Anderson; Sharon Stein Merkin; Susan A Everson-Rose; Rachel Widome; Teresa Seeman; Jared W Magnani; Carlos J Rodriguez; Pamela L Lutsey
Journal:  J Immigr Minor Health       Date:  2020-11-18
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