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Literature DB >> 26257040

Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI.

Robert R Flavell¹, Cornelius von Morze, Joseph E Blecha, David E Korenchan, Mark Van Criekinge, Renuka Sriram, Jeremy W Gordon, Hsin-Yu Chen, Sukumar Subramaniam, Robert A Bok, Zhen J Wang, Daniel B Vigneron, Peder E Larson, John Kurhanewicz, David M Wilson.

Abstract

N-(2-Acetamido)-2-aminoethanesulfonic acid (ACES), one of Good's buffers, was applied to pH imaging using hyperpolarized (13)C magnetic resonance spectroscopy. Rapid NMR- and MRI-based pH measurements were obtained by exploiting the sensitive pH-dependence of its (13)C chemical shift within the physiologic range.

Entities: Chemical Disease Gene Species

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Year: 2015 PMID： 26257040 PMCID： PMC4854286 DOI： 10.1039/c5cc05348j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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