Literature DB >> 26233853

Determined to Fail--the Role of Genetic Mechanisms in Heart Failure.

Elham Kayvanpour1,2, Hugo A Katus1,2, Benjamin Meder3,4.   

Abstract

Genetic variants contribute to several steps during heart failure pathophysiology. The mechanisms include frequent polymorphisms that increase the susceptibility to heart failure in the general population and rare variants as causes of an underlying cardiomyopathy. In this review, we highlight recent discoveries made by genetic approaches and provide an outlook onto the role of epigenetic modifiers of heart failure.

Entities:  

Keywords:  Cardiomyopathy; Gene mutation; Genetic polymorphism; Heart failure

Mesh：

Year:  2015        PMID： 26233853     DOI： 10.1007/s11897-015-0264-6

Source DB:  PubMed          Journal:  Curr Heart Fail Rep        ISSN： 1546-9530


  84 in total

1.  The Arg389Gly beta1-adrenoceptor polymorphism and catecholamine effects on plasma-renin activity.

Authors:  Heike Bruck; Kirsten Leineweber; Thomas Temme; Melanie Weber; Gerd Heusch; Thomas Philipp; Otto-Erich Brodde
Journal:  J Am Coll Cardiol       Date:  2005-11-04       Impact factor: 24.094

2.  Association of angiotensin-converting enzyme I/D polymorphism with heart failure: a meta-analysis.

Authors:  Yuanyuan Bai; Liang Wang; Shengshou Hu; Yingjie Wei
Journal:  Mol Cell Biochem       Date:  2011-10-21       Impact factor: 3.396

3.  Toward the blood-borne miRNome of human diseases.

Authors:  Andreas Keller; Petra Leidinger; Andrea Bauer; Abdou Elsharawy; Jan Haas; Christina Backes; Anke Wendschlag; Nathalia Giese; Christine Tjaden; Katja Ott; Jens Werner; Thilo Hackert; Klemens Ruprecht; Hanno Huwer; Junko Huebers; Gunnar Jacobs; Philip Rosenstiel; Henrik Dommisch; Arne Schaefer; Joachim Müller-Quernheim; Bernd Wullich; Bastian Keck; Norbert Graf; Joerg Reichrath; Britta Vogel; Almut Nebel; Sven U Jager; Peer Staehler; Ioannis Amarantos; Valesca Boisguerin; Cord Staehler; Markus Beier; Matthias Scheffler; Markus W Büchler; Joerg Wischhusen; Sebastian F M Haeusler; Johannes Dietl; Sylvia Hofmann; Hans-Peter Lenhof; Stefan Schreiber; Hugo A Katus; Wolfgang Rottbauer; Benjamin Meder; Joerg D Hoheisel; Andre Franke; Eckart Meese
Journal:  Nat Methods       Date:  2011-09-04       Impact factor: 28.547

4.  Polymorphisms of the beta1-adrenergic receptor predict exercise capacity in heart failure.

Authors:  Lynne E Wagoner; Laura L Craft; Paul Zengel; Nancy McGuire; Deborah A Rathz; Gerald W Dorn; Stephen B Liggett
Journal:  Am Heart J       Date:  2002-11       Impact factor: 4.749

5.  A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.

Authors:  Benjamin Meder; Frank Rühle; Tanja Weis; Georg Homuth; Andreas Keller; Jennifer Franke; Barbara Peil; Justo Lorenzo Bermejo; Karen Frese; Andreas Huge; Anika Witten; Britta Vogel; Jan Haas; Uwe Völker; Florian Ernst; Alexander Teumer; Philipp Ehlermann; Christian Zugck; Frauke Friedrichs; Heyo Kroemer; Marcus Dörr; Wolfgang Hoffmann; Bernhard Maisch; Sabine Pankuweit; Volker Ruppert; Thomas Scheffold; Uwe Kühl; Hans-Peter Schultheiss; Reinhold Kreutz; Georg Ertl; Christiane Angermann; Philippe Charron; Eric Villard; Françoise Gary; Richard Isnard; Michel Komajda; Matthias Lutz; Thomas Meitinger; Moritz F Sinner; H-Erich Wichmann; Michael Krawczak; Boris Ivandic; Dieter Weichenhan; Goetz Gelbrich; Nour-Eddine El-Mokhtari; Stefan Schreiber; Stephan B Felix; Gerd Hasenfuß; Arne Pfeufer; Norbert Hübner; Stefan Kääb; Eloisa Arbustini; Wolfgang Rottbauer; Norbert Frey; Monika Stoll; Hugo A Katus
Journal:  Eur Heart J       Date:  2013-07-12       Impact factor: 29.983

Review 6.  Chromatin remodeling in cardiovascular development and physiology.

Authors:  Pei Han; Calvin T Hang; Jin Yang; Ching-Pin Chang
Journal:  Circ Res       Date:  2011-02-04       Impact factor: 17.367

7.  Clinical profile of four families with arrhythmogenic right ventricular cardiomyopathy caused by dominant desmoplakin mutations.

Authors:  Barbara Bauce; Cristina Basso; Alessandra Rampazzo; Giorgia Beffagna; Luciano Daliento; Gianfranco Frigo; Sandro Malacrida; Luca Settimo; GianAntonio Danieli; Gaetano Thiene; Andrea Nava
Journal:  Eur Heart J       Date:  2005-06-07       Impact factor: 29.983

8.  Impact of genotype on clinical course in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated mutation carriers.

Authors:  Aditya Bhonsale; Judith A Groeneweg; Cynthia A James; Dennis Dooijes; Crystal Tichnell; Jan D H Jongbloed; Brittney Murray; Anneline S J M te Riele; Maarten P van den Berg; Hennie Bikker; Douwe E Atsma; Natasja M de Groot; Arjan C Houweling; Jeroen F van der Heijden; Stuart D Russell; Pieter A Doevendans; Toon A van Veen; Harikrishna Tandri; Arthur A Wilde; Daniel P Judge; J Peter van Tintelen; Hugh Calkins; Richard N Hauer
Journal:  Eur Heart J       Date:  2015-01-23       Impact factor: 29.983

9.  Clinicopathological profiles of progressive heart failure in hypertrophic cardiomyopathy.

Authors:  Paola Melacini; Cristina Basso; Annalisa Angelini; Chiara Calore; Fabiana Bobbo; Barbara Tokajuk; Nicoletta Bellini; Gessica Smaniotto; Mauro Zucchetto; Sabino Iliceto; Gaetano Thiene; Barry J Maron
Journal:  Eur Heart J       Date:  2010-05-31       Impact factor: 29.983

10.  Genetic deletion of arginine 14 in phospholamban causes dilated cardiomyopathy with attenuated electrocardiographic R amplitudes.

Authors:  Maximilian G Posch; Andreas Perrot; Christian Geier; Leif-Hendrik Boldt; Gunther Schmidt; Hans B Lehmkuhl; Roland Hetzer; Rainer Dietz; Matthias Gutberlet; Wilhelm Haverkamp; Cemil Ozcelik
Journal:  Heart Rhythm       Date:  2009-01-18       Impact factor: 6.343
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  7 in total

Review 1.  Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy: a meta-analysis on 7675 individuals.

Authors:  Farbod Sedaghat-Hamedani; Elham Kayvanpour; Oguz Firat Tugrul; Alan Lai; Ali Amr; Jan Haas; Tanja Proctor; Philipp Ehlermann; Katrin Jensen; Hugo A Katus; Benjamin Meder
Journal:  Clin Res Cardiol       Date:  2017-08-24       Impact factor: 5.460

2.  Clinical and genetic insights into non-compaction: a meta-analysis and systematic review on 7598 individuals.

Authors:  Elham Kayvanpour; Farbod Sedaghat-Hamedani; Weng-Tein Gi; Oguz Firat Tugrul; Ali Amr; Jan Haas; Feng Zhu; Philipp Ehlermann; Lorenz Uhlmann; Hugo A Katus; Benjamin Meder
Journal:  Clin Res Cardiol       Date:  2019-04-12       Impact factor: 5.460

Review 3.  Precision medicine for cardiovascular disease : Learning lessons from cardiomyopathies.

Authors:  F Sedaghat-Hamedani; H A Katus; B Meder
Journal:  Herz       Date:  2018-03       Impact factor: 1.443

Review 4.  Genotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals.

Authors:  Elham Kayvanpour; Farbod Sedaghat-Hamedani; Ali Amr; Alan Lai; Jan Haas; Daniel B Holzer; Karen S Frese; Andreas Keller; Katrin Jensen; Hugo A Katus; Benjamin Meder
Journal:  Clin Res Cardiol       Date:  2016-08-30       Impact factor: 5.460

5.  Personalized Computer Simulation of Diastolic Function in Heart Failure.

Authors:  Ali Amr; Elham Kayvanpour; Farbod Sedaghat-Hamedani; Tiziano Passerini; Viorel Mihalef; Alan Lai; Dominik Neumann; Bogdan Georgescu; Sebastian Buss; Derliz Mereles; Edgar Zitron; Andreas E Posch; Maximilian Würstle; Tommaso Mansi; Hugo A Katus; Benjamin Meder
Journal:  Genomics Proteomics Bioinformatics       Date:  2016-07-29       Impact factor: 7.691

6.  RBM20-Associated Ventricular Arrhythmias in a Patient with Structurally Normal Heart.

Authors:  Yuriy Vakhrushev; Alexandra Kozyreva; Andrey Semenov; Polina Sokolnikova; Tamara Lubimtseva; Dmitry Lebedev; Natalia Smolina; Sergey Zhuk; Lubov Mitrofanova; Elena Vasichkina; Anna Kostareva
Journal:  Genes (Basel)       Date:  2021-01-13       Impact factor: 4.096

7.  Identification of SCN5a p.C335R Variant in a Large Family with Dilated Cardiomyopathy and Conduction Disease.

Authors:  Farbod Sedaghat-Hamedani; Sabine Rebs; Ibrahim El-Battrawy; Safak Chasan; Tobias Krause; Jan Haas; Rujia Zhong; Zhenxing Liao; Qiang Xu; Xiaobo Zhou; Ibrahim Akin; Edgar Zitron; Norbert Frey; Katrin Streckfuss-Bömeke; Elham Kayvanpour
Journal:  Int J Mol Sci       Date:  2021-11-30       Impact factor: 5.923
  7 in total

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