Necati Duru1, Hasan Altinkaynak1, Şükran Erten2, Mehmet Erol Can1, Zeynep Duru3, Fatma Gülçin Uğurlu4, Nurullah Çağıl1. 1. a Department of Ophthalmology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey . 2. b Department of Rheumatology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey . 3. c Department of Ophthalmology , Ankara Numune Education and Research Hospital , Ankara , Turkey , and. 4. d Department of Physical Therapy and Rehabilitation , Ankara Atatürk Education and Research Hospital , Ankara , Turkey.
Abstract
PURPOSE: To investigate subfoveal and perifoveal choroidal thickness (CT) in patients with rheumatoid arthritis (RA). METHODS: A study group of 117 patients with RA and a control group of 46 age-matched healthy individuals were enrolled in the study. Subfoveal and perifoveal CTs were measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Perifoveal CT was measured 1,500 µm nasally and 1,500 µm temporally apart from the foveal center. Relationship between the disease activity score 28 (DAS-28) and subfoveal CT was also evaluated. RESULTS: The mean subfoveal CT values in the study and control groups were 226.90 ± 43.61 μm and 299.74 ± 48.06 μm, respectively, which made for a statistically significant difference (p < 0.001). Likewise, perifoveal CT values were significantly thinner in the study group when compared with control group. DAS-28 wasn't correlated with subfoveal CT in the study group. CONCLUSIONS: CT was significantly thinner in patients with RA when compared with healthy controls.
PURPOSE: To investigate subfoveal and perifoveal choroidal thickness (CT) in patients with rheumatoid arthritis (RA). METHODS: A study group of 117 patients with RA and a control group of 46 age-matched healthy individuals were enrolled in the study. Subfoveal and perifoveal CTs were measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Perifoveal CT was measured 1,500 µm nasally and 1,500 µm temporally apart from the foveal center. Relationship between the disease activity score 28 (DAS-28) and subfoveal CT was also evaluated. RESULTS: The mean subfoveal CT values in the study and control groups were 226.90 ± 43.61 μm and 299.74 ± 48.06 μm, respectively, which made for a statistically significant difference (p < 0.001). Likewise, perifoveal CT values were significantly thinner in the study group when compared with control group. DAS-28 wasn't correlated with subfoveal CT in the study group. CONCLUSIONS: CT was significantly thinner in patients with RA when compared with healthy controls.
Authors: Mehmet Erol Can; Fatma Efe Kaplan; Mehmet Murat Uzel; Hasan Kiziltoprak; Mustafa Cagri Ergun; Mustafa Koc; Gülcin Simsek Journal: Int Ophthalmol Date: 2017-08-05 Impact factor: 2.031