Mehmet Erol Can1, Fatma Efe Kaplan2, Mehmet Murat Uzel3, Hasan Kiziltoprak4, Mustafa Cagri Ergun2, Mustafa Koc4, Gülcin Simsek5. 1. Department of Ophthalmology, Kecioren Training and Research Hospital, Yasamkent Mah. 3208 Sk. Gulbeng Sitesi No: 1-49, Cankaya, Ankara, Turkey. drm.erolcan@gmail.com. 2. Department of Internal Medicine, Kecioren Training and Research Hospital, Ankara, Turkey. 3. Department of Ophthalmology, Elmadag State Hospital, Ankara, Turkey. 4. Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey. 5. Department of Pathology, Kecioren Training and Research Hospital, Ankara, Turkey.
Abstract
PURPOSE: To investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT). METHODS: The study included 25 patients with H. pylori infection and 25 healthy individuals as the control group. Helicobacter pylori patients were classified as the pre-treatment (Group 1; n: 25) and the post-treatment (Group 2; n: 25). RNFLT and CT were measured before and after treatment of H. pylori infection, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany). The axial length and intraocular pressure were also measured. RESULTS: The mean subfoveal CT was 320.96 ± 29.15 μm in Group 1 and 287.48 ± 49.17 in the control group (p = 0.007), while the mean subfoveal CT did not show any difference between Group 2 and the control group (p > 0.05). No statistically significant difference was determined between the H. pylori patients and the control group in respect of RNFLT values (p > 0.05). CONCLUSIONS: CT increases during H. pylori infection and returns to the normal range within 6 weeks of treatment. RNFLT does not show any change during H. pylori infection. The data related to the subfoveal CT may be useful in understanding the pathogenesis of central serous chorioretinopathy developing in H. pylori patients.
PURPOSE: To investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT). METHODS: The study included 25 patients with H. pyloriinfection and 25 healthy individuals as the control group. Helicobacter pyloripatients were classified as the pre-treatment (Group 1; n: 25) and the post-treatment (Group 2; n: 25). RNFLT and CT were measured before and after treatment of H. pyloriinfection, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany). The axial length and intraocular pressure were also measured. RESULTS: The mean subfoveal CT was 320.96 ± 29.15 μm in Group 1 and 287.48 ± 49.17 in the control group (p = 0.007), while the mean subfoveal CT did not show any difference between Group 2 and the control group (p > 0.05). No statistically significant difference was determined between the H. pyloripatients and the control group in respect of RNFLT values (p > 0.05). CONCLUSIONS: CT increases during H. pyloriinfection and returns to the normal range within 6 weeks of treatment. RNFLT does not show any change during H. pyloriinfection. The data related to the subfoveal CT may be useful in understanding the pathogenesis of central serous chorioretinopathy developing in H. pyloripatients.
Authors: L Cotticelli; M Borrelli; A C D'Alessio; M Menzione; A Villani; G Piccolo; F Montella; M R Iovene; M Romano Journal: Eur J Ophthalmol Date: 2006 Mar-Apr Impact factor: 2.597
Authors: Marieh Esmaeelpour; Boris Považay; Boris Hermann; Bernd Hofer; Vedran Kajic; Sarah L Hale; Rachel V North; Wolfgang Drexler; Nik J L Sheen Journal: Invest Ophthalmol Vis Sci Date: 2011-07-15 Impact factor: 4.799