Rafael Manfro1, Fabiano Silva Fonseca2, Marcelo Carlos Bortoluzzi3, Wilson Roberto Sendyk4. 1. Department of Dental Implantology, SOEBRAS, Street Presidente Coutinho 264/903, Florianópolis, SC CEP 88015-230 Brazil. 2. Vitória, ES Brazil. 3. Department of Implantodontic Maxillofacial Surgery, UNOESC, Joaçaba, SC Brazil. 4. UNISA, Santo Amaro, SP Brazil.
Abstract
INTRODUCTION: Anorganic bovine xenogenous grafts show the best performance as bone substitutes in implantodontics. Bio-Oss is the world's most widely used and investigated anorganic bone substitute. This article compares two anorganic bovine bone substitutes (Bone-Fill and Gen-Ox anorganic) with Bio-Oss. MATERIALS AND METHODS: Eight New Zealand rabbits were implanted with 4 titanium cylinders randomly filled with Bio-Oss, Bone-Fill, Gen-Ox anorganic or a blood clot. Four animals were sacrificed after 8 weeks; 12 weeks later, the remaining four were sacrificed. The contents of the cylinders were removed, cut and stained with HE before they were evaluated with an optical microscope. The samples were submitted to histomorphometry for analysis. RESULTS: The bone formation with Bio-Oss at 8 weeks was 8.43 mm(2); at 12 weeks, it was 9.32 mm(2). The bone formation with Bone-Fill at 8 weeks was 7.24 mm(2); at 12 weeks, it was 9.01 mm(2). The bone formation with Gen-Ox anorganic at 8 weeks was 2.78 mm(2); at 12 weeks, it was 3.02 mm(2). The bone formation with the blood clot at 8 weeks was 0.65 mm(2); at 12 weeks, it was 0.63 mm(2). CONCLUSION: Following this model, Bone-Fill was comparable to Bio-Oss and superior to Gen-Ox and blood clot.
INTRODUCTION: Anorganic bovine xenogenous grafts show the best performance as bone substitutes in implantodontics. Bio-Oss is the world's most widely used and investigated anorganic bone substitute. This article compares two anorganic bovine bone substitutes (Bone-Fill and Gen-Ox anorganic) with Bio-Oss. MATERIALS AND METHODS: Eight New Zealand rabbits were implanted with 4 titanium cylinders randomly filled with Bio-Oss, Bone-Fill, Gen-Ox anorganic or a blood clot. Four animals were sacrificed after 8 weeks; 12 weeks later, the remaining four were sacrificed. The contents of the cylinders were removed, cut and stained with HE before they were evaluated with an optical microscope. The samples were submitted to histomorphometry for analysis. RESULTS: The bone formation with Bio-Oss at 8 weeks was 8.43 mm(2); at 12 weeks, it was 9.32 mm(2). The bone formation with Bone-Fill at 8 weeks was 7.24 mm(2); at 12 weeks, it was 9.01 mm(2). The bone formation with Gen-Ox anorganic at 8 weeks was 2.78 mm(2); at 12 weeks, it was 3.02 mm(2). The bone formation with the blood clot at 8 weeks was 0.65 mm(2); at 12 weeks, it was 0.63 mm(2). CONCLUSION: Following this model, Bone-Fill was comparable to Bio-Oss and superior to Gen-Ox and blood clot.
Entities:
Keywords:
Anorganic bovine xenogenous graft; Bone reconstruction; Osseointegrated implants
Authors: James C Taylor; Sheldon E Cuff; James P L Leger; Amani Morra; Gail I Anderson Journal: Int J Oral Maxillofac Implants Date: 2002 May-Jun Impact factor: 2.804
Authors: Carlos E A Ferreira; Arthur B Novaes; Violet I Haraszthy; Márcio Bittencourt; Carolina B Martinelli; Sonia M Luczyszyn Journal: J Periodontol Date: 2009-12 Impact factor: 6.993
Authors: Amir Reza Rokn; Mohammad Amin Khodadoostan; Amir Ali Reza Rasouli Ghahroudi; Puria Motahhary; Mohammad Javad Kharrazi Fard; Hugo De Bruyn; Rose Afzalifar; Ehsan Soolar; Ahmad Soolari Journal: Open Dent J Date: 2011-07-07
Authors: María Piedad Ramírez Fernández; Sergio A Gehrke; Carlos Pérez Albacete Martinez; Jose L Calvo Guirado; Piedad N de Aza Journal: Materials (Basel) Date: 2017-05-17 Impact factor: 3.623
Authors: Gabriele Ceccarelli; Rossella Presta; Laura Benedetti; Maria Gabriella Cusella De Angelis; Saturnino Marco Lupi; Ruggero Rodriguez Y Baena Journal: Stem Cells Int Date: 2017-02-26 Impact factor: 5.443
Authors: Carlos Humberto Valencia-Llano; Diego López-Tenorio; Marcela Saavedra; Paula A Zapata; Carlos David Grande-Tovar Journal: Molecules Date: 2022-09-06 Impact factor: 4.927