Lauren M B Burke1, Mustafa R Bashir2, Frank H Miller3, Evan S Siegelman4, Michele Brown5, Mamdoh Alobaidy6, Tracy A Jaffe2, Shahid M Hussain7, Suzanne L Palmer8, Bonnie L Garon8, Aytekin Oto9, Caroline Reinhold10, Susan M Ascher11, Danielle K Demulder11, Stephen Thomas9, Shaun Best5, James Borer7, Ken Zhao3, Fanny Pinel-Giroux10, Isabela De Oliveira6, Daniel Resende6, Richard C Semelka6. 1. Department of Radiology, University of North Carolina, Chapel Hill, School of Medicine, Chapel Hill, NC. Electronic address: lauren_burke@med.unc.edu. 2. Department of Radiology, Duke University Medical Center, Durham, NC. 3. Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL. 4. Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA. 5. Department of Radiology, University of California, San Diego, School of Medicine, La Jolla, CA. 6. Department of Radiology, University of North Carolina, Chapel Hill, School of Medicine, Chapel Hill, NC. 7. Department of Radiology, University of Nebraska Medical Center, Omaha, NE. 8. Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA. 9. Department of Radiology, University of Chicago Medical Center, Chicago, IL. 10. Department of Radiology, Royal Victoria Hospital, McGill University Health Center, Montreal, QC, Canada. 11. Department of Radiology, Medstar Georgetown University Hospital, Washington, DC.
Abstract
OBJECTIVE: The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. STUDY DESIGN: In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution. RESULTS: Of the cases that were evaluated, 9.3% (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8%, 99.2%, 99.0%, 92.4%, and 99.7%, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99). CONCLUSION: MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy. Published by Elsevier Inc.
OBJECTIVE: The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. STUDY DESIGN: In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution. RESULTS: Of the cases that were evaluated, 9.3% (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8%, 99.2%, 99.0%, 92.4%, and 99.7%, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99). CONCLUSION: MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy. Published by Elsevier Inc.
Entities:
Keywords:
appendicitis; magnetic resonance imaging; pregnancy
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