Tibor Major1, Cristina Gutiérrez2, Benjamin Guix3, Emőke Mózsa4, Jean-Michel Hannoun-Levi5, Kristine Lössl6, Peter Niehoff7, Alexandra Resch8, Erik van Limbergen9, Csaba Polgár10. 1. Radiotherapy Centre, National Institute of Oncology, Budapest, Hungary. Electronic address: major@oncol.hu. 2. Department of Radiation Oncology, Catalan Institute of Oncology, Barcelona, Spain. 3. Radiation Oncology, Institute IMOR, Barcelona, Spain. 4. Institut of Radiooncology and Radiotherapy, Landesklinikum Wiener Neustadt, Wiener Neustadt, Austria. 5. Department of Radiation Oncology, Centre Antoine Lacassagne, Nice, France. 6. Department of Radiation Oncology, Inselspital-Bern University Hospital, Bern, Switzerland. 7. Department of Radiotherapy, Muncipal Hospital Cologne, Cologne, Germany. 8. Department of Radiotherapy and Radiobiology, University Hospital AKH Vienna, Vienna, Austria. 9. Department of Radiotherapy, University Hospital Gasthuisberg, Leuven, Belgium. 10. Radiotherapy Centre, National Institute of Oncology, Budapest, Hungary.
Abstract
PURPOSE: To investigate interobserver variations of target volume delineations in accelerated partial breast irradiation with multicatheter brachytherapy (BT) and to assess the impact of guidelines on consistency of contouring. METHODS AND MATERIALS: A contouring study with two phases in interstitial accelerated partial breast irradiation after open cavity surgery was conducted by the Groupe Européen de Curiethérapie-European Society for Radiotherapy and Oncology Breast Cancer Working Group. Contours of cavity and planning target volume (PTV) on preimplant and postimplant CT images were delineated. In Phase 1, nine radiation oncologists defined the target volumes of 5 patients, whereas in Phase 2, four observers draw the contours of 4 patients applying guidelines. In Phase 1, experience in breast BT after open cavity surgery was assessed. The delineations were compared between Phase 1 and Phase 2, the impact of guidelines was assessed, and cavity visualization score was related to consistency of delineations. RESULTS: Significant interobserver variability in delineations of lumpectomy cavity and PTV was observed among the participants. Observers with BT experience after open cavity surgery outlined the cavity and PTV more consistently (conformity indexgen: 0.52 vs. 0.48 and 0.59 vs. 0.55 for preimplant and postimplant cavities). For all volumes, the mean Vmax/Vmin was 2.2 vs. 2.8. Having used guidelines all conformity indices increased significantly. For cavity, the increase was 14% and 11%, whereas for the PTV, 28% and 17% on the preimplant and postimplant CT images, respectively. A strong correlation was found between consistency of contours and cavity visualization score. CONCLUSIONS: Simple guidelines on defining the lumpectomy cavity significantly increased the consistency of contouring. Reliable consistency of target volume definition can be expected only for good cavity visibility.
PURPOSE: To investigate interobserver variations of target volume delineations in accelerated partial breast irradiation with multicatheter brachytherapy (BT) and to assess the impact of guidelines on consistency of contouring. METHODS AND MATERIALS: A contouring study with two phases in interstitial accelerated partial breast irradiation after open cavity surgery was conducted by the Groupe Européen de Curiethérapie-European Society for Radiotherapy and Oncology Breast Cancer Working Group. Contours of cavity and planning target volume (PTV) on preimplant and postimplant CT images were delineated. In Phase 1, nine radiation oncologists defined the target volumes of 5 patients, whereas in Phase 2, four observers draw the contours of 4 patients applying guidelines. In Phase 1, experience in breast BT after open cavity surgery was assessed. The delineations were compared between Phase 1 and Phase 2, the impact of guidelines was assessed, and cavity visualization score was related to consistency of delineations. RESULTS: Significant interobserver variability in delineations of lumpectomy cavity and PTV was observed among the participants. Observers with BT experience after open cavity surgery outlined the cavity and PTV more consistently (conformity indexgen: 0.52 vs. 0.48 and 0.59 vs. 0.55 for preimplant and postimplant cavities). For all volumes, the mean Vmax/Vmin was 2.2 vs. 2.8. Having used guidelines all conformity indices increased significantly. For cavity, the increase was 14% and 11%, whereas for the PTV, 28% and 17% on the preimplant and postimplant CT images, respectively. A strong correlation was found between consistency of contours and cavity visualization score. CONCLUSIONS: Simple guidelines on defining the lumpectomy cavity significantly increased the consistency of contouring. Reliable consistency of target volume definition can be expected only for good cavity visibility.
Authors: Csaba Polgár; Zsuzsanna Kahán; Olivera Ivanov; Martin Chorváth; Andrea Ligačová; András Csejtei; Gabriella Gábor; László Landherr; László Mangel; Árpád Mayer; János Fodor Journal: Pathol Oncol Res Date: 2022-06-23 Impact factor: 2.874
Authors: Benjamin T Cooper; Anuj Goenka; Kevin Sine; Jae Y Lee; Brian H Chon; Henry K Tsai; Eugen B Hug; Hiral P Fontanilla Journal: Int J Part Ther Date: 2020-06-22
Authors: André Toussaint; Anne Richter; Frederick Mantel; John C Flickinger; Inga Siiner Grills; Neelam Tyagi; Arjun Sahgal; Daniel Letourneau; Jason P Sheehan; David J Schlesinger; Peter Carlos Gerszten; Matthias Guckenberger Journal: Radiat Oncol Date: 2016-04-18 Impact factor: 3.481