BACKGROUND: Swept source optical coherence tomography (SS-OCT, Topcon Medical System, Japan) is known to have longer wavelength than spectral domain OCT (SD-OCT, Spectralis, Heidelberg Engineering, Germany), allowing a deeper penetration into retina and choroidal layers. This objective of this study was to compare the visibility of retinal and choroidal features in polypoidal choroidal vasculopathy (PCV) using SS-OCT and SD-OCT. DESIGN: This study employs prospective comparative observational case series in Singapore National Eye Center. PARTICIPANTS: There were 20 eyes (20 patients) with PCV confirmed with indocyanine green angiogram. METHODS: Six pre-specified OCT parameters (presence of polyps, sharp pigment epithelial detachment [PED] peak, notched PED and visibility of full maximum height of PED, inner segment/outer segment [IS/OS] line and choroid-scleral interface [CSI]) were graded using SS-OCT and SD-OCT. MAIN OUTCOME MEASURES: The Kappa statistics between the two imaging modalities were calculated. RESULTS: Both SS-OCT and SD-OCT were able to detect polypoidal lesions in the majority of eyes (90% and 85%, respectively). However, SS-OCT had better detection for CSI and IS/OS lines (CSI: 80% vs 45%, P = 0.05; IS/OS line: 65% vs 45%, P = 0.34). For sharp PED peak, notched PED, ability to visualize the full PED height and retinal pigment epithelial line, both OCT machines were able to detect in ≥80% of the eyes. CONCLUSION: In conclusion, SS-OCT and SD-OCT appeared to be similarly effective at detecting most features associated with PCV. However, SS-OCT is more superior in detecting the CSI.
BACKGROUND: Swept source optical coherence tomography (SS-OCT, Topcon Medical System, Japan) is known to have longer wavelength than spectral domain OCT (SD-OCT, Spectralis, Heidelberg Engineering, Germany), allowing a deeper penetration into retina and choroidal layers. This objective of this study was to compare the visibility of retinal and choroidal features in polypoidal choroidal vasculopathy (PCV) using SS-OCT and SD-OCT. DESIGN: This study employs prospective comparative observational case series in Singapore National Eye Center. PARTICIPANTS: There were 20 eyes (20 patients) with PCV confirmed with indocyanine green angiogram. METHODS: Six pre-specified OCT parameters (presence of polyps, sharp pigment epithelial detachment [PED] peak, notched PED and visibility of full maximum height of PED, inner segment/outer segment [IS/OS] line and choroid-scleral interface [CSI]) were graded using SS-OCT and SD-OCT. MAIN OUTCOME MEASURES: The Kappa statistics between the two imaging modalities were calculated. RESULTS: Both SS-OCT and SD-OCT were able to detect polypoidal lesions in the majority of eyes (90% and 85%, respectively). However, SS-OCT had better detection for CSI and IS/OS lines (CSI: 80% vs 45%, P = 0.05; IS/OS line: 65% vs 45%, P = 0.34). For sharp PED peak, notched PED, ability to visualize the full PED height and retinal pigment epithelial line, both OCT machines were able to detect in ≥80% of the eyes. CONCLUSION: In conclusion, SS-OCT and SD-OCT appeared to be similarly effective at detecting most features associated with PCV. However, SS-OCT is more superior in detecting the CSI.
Authors: K Takayama; Y Ito; H Kaneko; K Kataoka; T Sugita; R Maruko; K Hattori; E Ra; F Haga; H Terasaki Journal: Eye (Lond) Date: 2016-11-04 Impact factor: 3.775
Authors: Eduardo A Novais; Mehreen Adhi; Eric M Moult; Ricardo N Louzada; Emily D Cole; Lennart Husvogt; ByungKun Lee; Sabin Dang; Caio V S Regatieri; André J Witkin; Caroline R Baumal; Joachim Hornegger; Vijaysekhar Jayaraman; James G Fujimoto; Jay S Duker; Nadia K Waheed Journal: Am J Ophthalmol Date: 2016-02-04 Impact factor: 5.258
Authors: Daniel Shu Wei Ting; Yasuo Yanagi; Rupesh Agrawal; Hwei Yee Teo; Sophia Seen; Ian Yew San Yeo; Ranjana Mathur; Choi Mun Chan; Shu Yen Lee; Edmund Yick Mun Wong; Doric Wong; Tien Yin Wong; Gemmy Chui Ming Cheung Journal: Sci Rep Date: 2017-08-11 Impact factor: 4.379
Authors: Qinqin Zhang; Chieh-Li Chen; Zhongdi Chu; Fang Zheng; Andrew Miller; Luiz Roisman; Joao Rafael de Oliveira Dias; Zohar Yehoshua; Karen B Schaal; William Feuer; Giovanni Gregori; Sophie Kubach; Lin An; Paul F Stetson; Mary K Durbin; Philip J Rosenfeld; Ruikang K Wang Journal: Invest Ophthalmol Vis Sci Date: 2017-03-01 Impact factor: 4.799
Authors: Chun On Lee; Xiujuan Zhang; Nan Yuan; Shumin Tang; Li Jia Chen; Carol Y Cheung; Jason C Yam Journal: Sci Rep Date: 2021-07-02 Impact factor: 4.379