Literature DB >> 2618109

Indications for adaptation to differently high vitamin C supplies in guinea pigs. 1. Development of ascorbic acid levels after altered dosing.

E Degkwitz1, R H Bödeker.   

Abstract

Guinea pigs supplied with 5 mg/100 g vitamin in the food seem to be at the marginal substitution for a survival and show no ability to adapt the ascorbic acid metabolism to this low support. Guinea pigs longlastingly (6-8 weeks) supplied with 20 mg/100 g or 680 mg/100 g vitamin C in the food show the typical symptoms of an evolving adaptation by an overshooting in the course of the ascorbic acid levels in several organs after a switch to an extremely different vitamin C supply.

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Year:  1989        PMID： 2618109     DOI： 10.1007/bf02019396

Source DB:  PubMed          Journal:  Z Ernahrungswiss        ISSN： 0044-264X


  7 in total

Review 1.  Chemistry and metabolism of ascorbic acid and ascorbate sulfate.

Authors:  B M Tolbert; M Downing; R W Carlson; M K Knight; E M Baker
Journal:  Ann N Y Acad Sci       Date:  1975-09-30       Impact factor: 5.691

2.  Catabolism of L-ascorbic-1-C14 acid as a measure of its utilization in the intact and wounded guinea pig on scorbutic, maintenance, and saturation diets.

Authors:  A F ABT; S VON SCHUCHING
Journal:  Ann N Y Acad Sci       Date:  1961-04-21       Impact factor: 5.691

3.  [Can water-soluble vitamins be over-dosed? Research on vitamin C].

Authors:  T GORDONOFF
Journal:  Schweiz Med Wochenschr       Date:  1960-07-02

4.  [Decrease of cytochrome contents and changes in the kinetics of monooxygenase in liver microsomes of guinea pigs at various stages of L-ascorbic acid].

Authors:  E Degkwitz; L Höchli-Kaufmann; D Luft; H Staudinger
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1972-07

5.  Indications for adaptation to differently high vitamin C supplies in guinea pigs. 2. Development of hepatic amounts of microsomal protein and cytochromes (P-450, b5) after altered dosing.

Authors:  E Degkwitz; R H Bödeker
Journal:  Z Ernahrungswiss       Date:  1989-12

6.  Comparative studies on the influence of L-ascorbate, D-arabino-ascorbate and 5-oxo-D-gluconate on the amounts of cytochromes P-450 and b5 in liver microsomes of guinea pigs.

Authors:  E Degkwitz; K S Kim
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1973-05

7.  Characterization of guinea pigs adapted to differently high vitamin C supplies. 1. Blood-levels of cholesterol, glucose, triacylglycerides and hemoglobin.

Authors:  E Degkwitz; R Bödeker
Journal:  Z Ernahrungswiss       Date:  1990-03
  7 in total

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