Literature DB >> 26167251

Impact of geography on organ allocation: Beyond the distance to the transplantation center.

Rony Ghaoui1, Jane Garb1, Fredric Gordon1, Elizabeth Pomfret1.   

Abstract

AIM: To illustrate the application and utility of Geographic Information System (GIS) in exploring patterns of liver transplantation. Specifically, we aim to describe the geographic distribution of transplant registrations and identify disparities in access to liver transplantation across United Network of Organ Sharing (UNOS) region 1.
METHODS: Based on UNOS data, the number of listed transplant candidates by ZIP code from 2003 to 2012 for Region 1 was obtained. Choropleth (color-coded) maps were used to visualize the geographic distribution of transplant registrations across the region. Spatial interaction analysis was used to analyze the geographic pattern of total transplant registrations by ZIP code. Factors tested included ZIP code log population and log distance from each ZIP code to the nearest transplant center; ZIP code population density; distance from the nearest city over 50000; and dummy variables for state residence and location in the southern portion of the region.
RESULTS: Visualization of transplant registrations revealed geographic disparities in organ allocation across Region 1. The total number of registrations was highest in the southern portion of the region. Spatial interaction analysis, after adjusting for the size of the underlying population, revealed statistically significant clustering of high and low rates in several geographic areas could not be predicted based solely on distance to the transplant center or density of population.
CONCLUSION: GIS represents a new method to evaluate the access to liver transplantation within one region and can be used to identify the presence of disparities and reasons for their existence in order to alleviate them.

Entities:  

Keywords:  Health geographic’s; Healthcare disparities; Outcome research

Year:  2015        PMID: 26167251      PMCID: PMC4491907          DOI: 10.4254/wjh.v7.i13.1782

Source DB:  PubMed          Journal:  World J Hepatol


  11 in total

1.  Outcomes of treatment for hepatitis C virus infection by primary care providers.

Authors:  Sanjeev Arora; Karla Thornton; Glen Murata; Paulina Deming; Summers Kalishman; Denise Dion; Brooke Parish; Thomas Burke; Wesley Pak; Jeffrey Dunkelberg; Martin Kistin; John Brown; Steven Jenkusky; Miriam Komaromy; Clifford Qualls
Journal:  N Engl J Med       Date:  2011-06-01       Impact factor: 91.245

2.  Geographic disparities in access to organ transplant in France.

Authors:  Françoise Roudot-Thoraval; Philippe Romano; Francis Spaak; Didier Houssin; Isabelle Durand-Zaleski
Journal:  Transplantation       Date:  2003-11-15       Impact factor: 4.939

3.  Rural residency and the risk of mortality while waiting for liver transplantation.

Authors:  Paul Douglas Renfrew; Michele Molinari
Journal:  Clin Transplant       Date:  2011-12-28       Impact factor: 2.863

4.  Impact of geographic disparity on liver allocation for hepatocellular cancer in the United States.

Authors:  Zakiyah Kadry; Eric W Schaefer; Tadahiro Uemura; Ali Riaz Shah; Ian Schreibman; Thomas R Riley
Journal:  J Hepatol       Date:  2011-10-23       Impact factor: 25.083

Review 5.  Hepatocellular carcinoma.

Authors:  Hashem B El-Serag
Journal:  N Engl J Med       Date:  2011-09-22       Impact factor: 91.245

6.  Geographic differences in event rates by model for end-stage liver disease score.

Authors:  J P Roberts; D M Dykstra; N P Goodrich; S H Rush; R M Merion; F K Port
Journal:  Am J Transplant       Date:  2006-10       Impact factor: 8.086

7.  Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008.

Authors:  Zobair M Younossi; Maria Stepanova; Mariam Afendy; Yun Fang; Youssef Younossi; Hesham Mir; Manirath Srishord
Journal:  Clin Gastroenterol Hepatol       Date:  2011-03-25       Impact factor: 11.382

8.  Addressing geographic disparities in liver transplantation through redistricting.

Authors:  S E Gentry; A B Massie; S W Cheek; K L Lentine; E H Chow; C E Wickliffe; N Dzebashvili; P R Salvalaggio; M A Schnitzler; D A Axelrod; D L Segev
Journal:  Am J Transplant       Date:  2013-07-09       Impact factor: 8.086

9.  Increase in mortality rate of liver transplant candidates residing in specific geographic areas: analysis of UNOS data.

Authors:  D Zorzi; C Rastellini; D H Freeman; G Elias; A Duchini; L Cicalese
Journal:  Am J Transplant       Date:  2012-08       Impact factor: 8.086

10.  Impact of geographic location on access to liver transplantation among ethnic minorities.

Authors:  Nyingi Kemmer; Kamran Safdar; Tiffany Kaiser; Victoria Zacharias; Guy W Neff
Journal:  Transplantation       Date:  2008-01-27       Impact factor: 4.939

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  1 in total

1.  Stereotactic body radiotherapy used as a bridge to liver transplant in patients with hepatocellular carcinoma and Child-Pugh score ≥8 cirrhosis.

Authors:  Steven Gresswell; Rachel Tobillo; Shaakir Hasan; Tadahiro Uemura; Lorenzo Machado; Ngoc Thai; Alexander Kirichenko
Journal:  J Radiosurg SBRT       Date:  2018
  1 in total

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