Literature DB >> 26166859

The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin.

Grzegorz Zięba1, Marcin Rojkiewicz1, Violetta Kozik1, Krystyna Jarzembek1, Anna Jarczyk1, Aleksander Sochanik2, Piotr Kuś1.   

Abstract

ABSTRACT: A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, 1H NMR, UV-visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromatography with use of log PRekker. These porphyrins are potential photosensitizers in photodynamic therapy. GRAPHICAL ABSTRACT: .

Entities:  

Keywords:  Fluorescence spectroscopy; Hydrophobicity; Porphyrins; Sensitizers

Year:  2011        PMID： 26166859      PMCID： PMC4494763          DOI： 10.1007/s00706-011-0586-3

Source DB:  PubMed          Journal:  Monatsh Chem        ISSN： 0026-9247            Impact factor:   1.451


  10 in total

1.  The depth of porphyrin in a membrane and the membrane's physical properties affect the photosensitizing efficiency.

Authors:  Adina Lavi; Hana Weitman; Robert T Holmes; Kevin M Smith; Benjamin Ehrenberg
Journal:  Biophys J       Date:  2002-04       Impact factor: 4.033

2.  On the double role of photofrin as a photo- and a radio-sensitising agent: a possible new combination therapy for tumours.

Authors:  Moshe Schaffer; Pamela M Schaffer; Alfons Hofstetter; Eckhart Dühmke; Giulio Jori
Journal:  Photochem Photobiol Sci       Date:  2002-06       Impact factor: 3.982

3.  On the correlation between hydrophobicity, liposome binding and cellular uptake of porphyrin sensitizers.

Authors:  Shimshon Ben-Dror; Irena Bronshtein; Arno Wiehe; Beate Röder; Mathias O Senge; Benjamin Ehrenberg
Journal:  Photochem Photobiol       Date:  2006 May-Jun       Impact factor: 3.421

Review 4.  Photophysical properties of porphyrins in biological membranes.

Authors:  F Ricchelli
Journal:  J Photochem Photobiol B       Date:  1995-08       Impact factor: 6.252

5.  Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: potential agents for photodynamic therapy of cancers.

Authors:  Vincent Sol; François Lamarche; Michaela Enache; Guillaume Garcia; Robert Granet; Michel Guilloton; J C Blais; Pierre Krausz
Journal:  Bioorg Med Chem       Date:  2005-11-02       Impact factor: 3.641

6.  Interaction of tetraphenyl-porphyrin derivatives with DPPC-liposomes: an EPR study.

Authors:  István Voszka; Zsófia Szabó; Gabriella Csík; Philip Maillard; Pál Gróf
Journal:  J Photochem Photobiol B       Date:  2005-01-22       Impact factor: 6.252

7.  Incorporation of hydrophobic porphyrins into liposomes: characterization and structural requirements.

Authors:  F Postigo; M Mora; M A De Madariaga; S Nonell; M L Sagristá
Journal:  Int J Pharm       Date:  2004-07-08       Impact factor: 5.875

Review 8.  Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy.

Authors:  Emma S Nyman; Paavo H Hynninen
Journal:  J Photochem Photobiol B       Date:  2004-01-23       Impact factor: 6.252

9.  New strategy for targeting of photosensitizers. Synthesis of glycodendrimeric phenylporphyrins, incorporation into a liposome membrane and interaction with a specific lectin.

Authors:  Séverine Ballut; Ali Makky; Bernard Loock; Jean-Philippe Michel; Philippe Maillard; Véronique Rosilio
Journal:  Chem Commun (Camb)       Date:  2008-11-19       Impact factor: 6.222

10.  Halogen atom effect on photophysical and photodynamic characteristics of derivatives of 5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin.

Authors:  A C Serra; M Pineiro; A M d'A Rocha Gonsalves; M Abrantes; M Laranjo; A C Santos; M F Botelho
Journal:  J Photochem Photobiol B       Date:  2008-04-27       Impact factor: 6.252
  10 in total

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