Literature DB >> 26141629

The Effect of Genetic Counseling on Knowledge and Perceptions Regarding Risks for Breast Cancer.

M Sagi1, L Kaduri, J Zlotogora, T Peretz.   

Abstract

In 1994, a clinic for cancer risk counseling was opened at Hadassah University Hospital in Jerusalem. Most of the counselees have been women who had breast cancer and/or a relative with breast cancer. In order to evaluate the effect of this counseling on women's knowledge and perceptions regarding the risks for breast cancer, a questionnaire was given before and after the counseling session to 60 healthy women who came to the clinic because they have relatives with breast cancer. According to the genetic counselors' estimations, most of these women had a significantly increased risk (compared to the general population) of developing cancer. Before counseling, the women overestimated the population risk for breast cancer, the contribution of heredity to morbidity of cancer, and their own risks to get cancer. After counseling session, they gave reduced estimates, closer to the "real" ones. The subjective perceptions regarding these risks were reduced after counseling, except for the perceptions regarding their relativerisks which have not changed after the counseling. About 90% of the women who came to the clinic wanted to be tested for genetic predisposition to cancer. For most of these women, the expectations that the test can rule out a genetic predisposition to cancer became more realistic after the counseling. The option to first test an affected relative was offered to all families, and a test was actually conducted in 75% of the families.

Entities:  

Year:  1998        PMID: 26141629     DOI: 10.1023/A:1022880831996

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  36 in total

1.  Age at onset as an indicator of familial risk of breast cancer.

Authors:  E B Claus; N J Risch; W D Thompson
Journal:  Am J Epidemiol       Date:  1990-06       Impact factor: 4.897

2.  Informed consent and BRCA1 testing.

Authors:  G Geller; B A Bernhardt; K Helzlsouer; N A Holtzman; M Stefanek; P M Wilcox
Journal:  Nat Genet       Date:  1995-12       Impact factor: 38.330

3.  Assessment and counseling for women with a family history of breast cancer. A guide for clinicians.

Authors:  K F Hoskins; J E Stopfer; K A Calzone; S D Merajver; T R Rebbeck; J E Garber; B L Weber
Journal:  JAMA       Date:  1995-02-15       Impact factor: 56.272

4.  The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals.

Authors:  J P Struewing; D Abeliovich; T Peretz; N Avishai; M M Kaback; F S Collins; L C Brody
Journal:  Nat Genet       Date:  1995-10       Impact factor: 38.330

5.  Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

Authors:  D F Easton; D T Bishop; D Ford; G P Crockford
Journal:  Am J Hum Genet       Date:  1993-04       Impact factor: 11.025

6.  Attitudes of obstetrician-gynecologists toward DNA testing for a genetic susceptibility to breast cancer.

Authors:  P T Rowley; S Loader
Journal:  Obstet Gynecol       Date:  1996-10       Impact factor: 7.661

7.  Genetic counseling for families with inherited susceptibility to breast and ovarian cancer.

Authors:  B B Biesecker; M Boehnke; K Calzone; D S Markel; J E Garber; F S Collins; B L Weber
Journal:  JAMA       Date:  1993-04-21       Impact factor: 56.272

8.  Psychological aspects of genetic counseling. IV. The subjective assessment of probability.

Authors:  S Kessler; E K Levine
Journal:  Am J Med Genet       Date:  1987-10

9.  Familial breast cancer: a controlled study of risk perception, psychological morbidity and health beliefs in women attending for genetic counselling.

Authors:  S Lloyd; M Watson; B Waites; L Meyer; R Eeles; S Ebbs; A Tylee
Journal:  Br J Cancer       Date:  1996-08       Impact factor: 7.640

10.  The impact of genetic counselling on risk perception in women with a family history of breast cancer.

Authors:  D G Evans; V Blair; R Greenhalgh; P Hopwood; A Howell
Journal:  Br J Cancer       Date:  1994-11       Impact factor: 7.640

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  6 in total

Review 1.  How risk is perceived, constructed and interpreted by clients in clinical genetics, and the effects on decision making: systematic review.

Authors:  Stephanie Sivell; Glyn Elwyn; Clara L Gaff; Angus J Clarke; Rachel Iredale; Chris Shaw; Joanna Dundon; Hazel Thornton; Adrian Edwards
Journal:  J Genet Couns       Date:  2007-10-30       Impact factor: 2.537

2.  Concerns about inherited risk of breast cancer prior to diagnosis in Japanese patients with breast complaints.

Authors:  Noriko Ando; Yumi Iwamitsu; Masaru Kuranami; Shigemi Okazaki; Kenji Yamamoto; Masahiko Watanabe; Hitoshi Miyaoka
Journal:  Fam Cancer       Date:  2011-12       Impact factor: 2.375

3.  Topics and sources of memorable breast cancer messages and their impact on prevention and detection behaviors.

Authors:  Sandi W Smith; Samantha Nazione; Carolyn Laplante; Michael R Kotowski; Charles Atkin; Christine M Skubisz; Cynthia Stohl
Journal:  J Health Commun       Date:  2009 Apr-May

4.  Patient satisfaction with cancer genetic counseling: a psychometric analysis of the Genetic Counseling Satisfaction Scale.

Authors:  Tiffani A DeMarco; Beth N Peshkin; Bryn D Mars; Kenneth P Tercyak
Journal:  J Genet Couns       Date:  2004-08       Impact factor: 2.537

5.  Evaluation of group genetic counseling for hereditary breast and ovarian cancer.

Authors:  Yolanda Ridge; Karen Panabaker; Mary McCullum; Cheryl Portigal-Todd; Jenna Scott; Barbara McGillivray
Journal:  J Genet Couns       Date:  2009-01-06       Impact factor: 2.537

Review 6.  Psychological impact of genetic counseling for familial cancer: a systematic review and meta-analysis.

Authors:  Dejana Braithwaite; Jon Emery; Fiona Walter; A Toby Prevost; Stephen Sutton
Journal:  Fam Cancer       Date:  2006       Impact factor: 2.375

  6 in total

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