Literature DB >> 26122457

A Critical Examination of the "Bad Luck" Explanation of Cancer Risk.

Andrii I Rozhok1, Geoffrey M Wahl2, James DeGregori3.   

Abstract

Tomasetti and Vogelstein (1) argue that lifetime cancer risk for particular tissues is mostly determined by the total number of stem cell (SC) divisions within the tissue, whereby most cancers arise due to "bad luck"—mutations occurring during DNA replication. We argue that the poorly substantiated estimations of SC division parameters and assumptions that oversimplify somatic evolution prevent such a conclusion from being drawn. ©2015 American Association for Cancer Research.

Entities:  

Mesh：

Year:  2015        PMID： 26122457      PMCID： PMC4849411          DOI： 10.1158/1940-6207.CAPR-15-0229

Source DB:  PubMed          Journal:  Cancer Prev Res (Phila)        ISSN： 1940-6215


  21 in total

1.  Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.

Authors:  Hugo J Snippert; Laurens G van der Flier; Toshiro Sato; Johan H van Es; Maaike van den Born; Carla Kroon-Veenboer; Nick Barker; Allon M Klein; Jacco van Rheenen; Benjamin D Simons; Hans Clevers
Journal:  Cell       Date:  2010-10-01       Impact factor: 41.582

2.  Intestinal stem cell replacement follows a pattern of neutral drift.

Authors:  Carlos Lopez-Garcia; Allon M Klein; Benjamin D Simons; Douglas J Winton
Journal:  Science       Date:  2010-09-23       Impact factor: 47.728

3.  The replication rate of human hematopoietic stem cells in vivo.

Authors:  Sandra N Catlin; Lambert Busque; Rosemary E Gale; Peter Guttorp; Janis L Abkowitz
Journal:  Blood       Date:  2011-02-22       Impact factor: 22.113

4.  Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.

Authors:  Yann Malato; Syed Naqvi; Nina Schürmann; Raymond Ng; Bruce Wang; Joan Zape; Mark A Kay; Dirk Grimm; Holger Willenbring
Journal:  J Clin Invest       Date:  2011-11-21       Impact factor: 14.808

5.  Long-lived intestinal tuft cells serve as colon cancer-initiating cells.

Authors:  C Benedikt Westphalen; Samuel Asfaha; Yoku Hayakawa; Yoshihiro Takemoto; Dana J Lukin; Andreas H Nuber; Anna Brandtner; Wanda Setlik; Helen Remotti; Ashlesha Muley; Xiaowei Chen; Randal May; Courtney W Houchen; James G Fox; Michael D Gershon; Michael Quante; Timothy C Wang
Journal:  J Clin Invest       Date:  2014-03       Impact factor: 14.808

Review 6.  Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?

Authors:  J DeGregori
Journal:  Oncogene       Date:  2012-07-02       Impact factor: 9.867

Review 7.  The plastic pancreas.

Authors:  Oren Ziv; Benjamin Glaser; Yuval Dor
Journal:  Dev Cell       Date:  2013-07-15       Impact factor: 12.270

8.  Defining stem cell dynamics in models of intestinal tumor initiation.

Authors:  Louis Vermeulen; Edward Morrissey; Maartje van der Heijden; Anna M Nicholson; Andrea Sottoriva; Simon Buczacki; Richard Kemp; Simon Tavaré; Douglas J Winton
Journal:  Science       Date:  2013-11-22       Impact factor: 47.728

9.  A single progenitor population switches behavior to maintain and repair esophageal epithelium.

Authors:  David P Doupé; Maria P Alcolea; Amit Roshan; Gen Zhang; Allon M Klein; Benjamin D Simons; Philip H Jones
Journal:  Science       Date:  2012-07-19       Impact factor: 47.728

10.  DNA methylation age of human tissues and cell types.

Authors:  Steve Horvath
Journal:  Genome Biol       Date:  2013       Impact factor: 13.583
View more
  13 in total

Review 1.  Somatic mosaicism: on the road to cancer.

Authors:  Luis C Fernández; Miguel Torres; Francisco X Real
Journal:  Nat Rev Cancer       Date:  2015-12-18       Impact factor: 60.716

Review 2.  Big Bang Tumor Growth and Clonal Evolution.

Authors:  Ruping Sun; Zheng Hu; Christina Curtis
Journal:  Cold Spring Harb Perspect Med       Date:  2018-05-01       Impact factor: 6.915

3.  Health Equity and the Fallacy of Treating Causes of Population Health as if They Sum to 100.

Authors:  Nancy Krieger
Journal:  Am J Public Health       Date:  2017-04       Impact factor: 9.308

Review 4.  The Warburg Effect and Mass Spectrometry-based Proteomic Analysis.

Authors:  Weidong Zhou; Lance A Liotta; Emanuel F Petricoin
Journal:  Cancer Genomics Proteomics       Date:  2017 Jul-Aug       Impact factor: 4.069

5.  Stem cells, environment, and cancer risk.

Authors:  Anna H Zhao
Journal:  Stem Cell Investig       Date:  2015-12-31

Review 6.  A population genetics perspective on the determinants of intra-tumor heterogeneity.

Authors:  Zheng Hu; Ruping Sun; Christina Curtis
Journal:  Biochim Biophys Acta Rev Cancer       Date:  2017-03-06       Impact factor: 10.680

Review 7.  Unraveling Hematopoiesis through the Lens of Genomics.

Authors:  L Alexander Liggett; Vijay G Sankaran
Journal:  Cell       Date:  2020-09-17       Impact factor: 41.582

8.  Tumorigenesis as the Paradigm of Quasi-neutral Molecular Evolution.

Authors:  Bingjie Chen; Zongkun Shi; Qingjian Chen; Xu Shen; Darryl Shibata; Haijun Wen; Chung-I Wu
Journal:  Mol Biol Evol       Date:  2019-07-01       Impact factor: 16.240

9.  Preventable Incidence and Mortality of Carcinoma Associated With Lifestyle Factors Among White Adults in the United States.

Authors:  Mingyang Song; Edward Giovannucci
Journal:  JAMA Oncol       Date:  2016-09-01       Impact factor: 31.777

10.  Determining cancer risk: the evolutionary multistage model or total stem cell divisions?

Authors:  Leonard Nunney; Kevin Thai
Journal:  Proc Biol Sci       Date:  2020-12-16       Impact factor: 5.349
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.