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Literature DB >> 26115196

Accelerating the Translation of Nanomaterials in Biomedicine.

Samir Mitragotri¹, Daniel G Anderson², Xiaoyuan Chen³, Edward K Chow⁴, Dean Ho⁵, Alexander V Kabanov⁶, Jeffrey M Karp⁷, Kazunori Kataoka⁸, Chad A Mirkin⁹, Sarah Hurst Petrosko⁹, Jinjun Shi, Molly M Stevens¹⁰, Shouheng Sun¹¹, Sweehin Teoh, Subbu S Venkatraman, Younan Xia¹², Shutao Wang¹³, Zhen Gu^14,15,16, Chenjie Xu.

Abstract

Due to their size and tailorable physicochemical properties, nanomaterials are an emerging class of structures utilized in biomedical applications. There are now many prominent examples of nanomaterials being used to improve human health, in areas ranging from imaging and diagnostics to therapeutics and regenerative medicine. An overview of these examples reveals several common areas of synergy and future challenges. This Nano Focus discusses the current status and future potential of promising nanomaterials and their translation from the laboratory to the clinic, by highlighting a handful of successful examples.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2015 PMID： 26115196 PMCID： PMC5227554 DOI： 10.1021/acsnano.5b03569

Source DB: PubMed Journal: ACS Nano ISSN： 1936-0851 Impact factor: 15.881

81 in total

1. Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier.

Authors: Yutaka Miura; Tomoya Takenaka; Kazuko Toh; Shourong Wu; Hiroshi Nishihara; Mitsunobu R Kano; Yasushi Ino; Takahiro Nomoto; Yu Matsumoto; Hiroyuki Koyama; Horacio Cabral; Nobuhiro Nishiyama; Kazunori Kataoka
Journal: ACS Nano Date: 2013-09-18 Impact factor: 15.881

2. Nano-flares: probes for transfection and mRNA detection in living cells.

Authors: Dwight S Seferos; David A Giljohann; Haley D Hill; Andrew E Prigodich; Chad A Mirkin
Journal: J Am Chem Soc Date: 2007-11-23 Impact factor: 15.419

3. The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles. Micelles as microcontainers for drug targeting.

Authors: A V Kabanov; V P Chekhonin; E V Batrakova; A S Lebedev; N S Melik-Nubarov; S A Arzhakov; A V Levashov; G V Morozov; E S Severin
Journal: FEBS Lett Date: 1989-12-04 Impact factor: 4.124

4. Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making.

Authors: Hilary Godwin; Catherine Nameth; David Avery; Lynn L Bergeson; Daniel Bernard; Elizabeth Beryt; William Boyes; Scott Brown; Amy J Clippinger; Yoram Cohen; Maria Doa; Christine Ogilvie Hendren; Patricia Holden; Keith Houck; Agnes B Kane; Frederick Klaessig; Toivo Kodas; Robert Landsiedel; Iseult Lynch; Timothy Malloy; Mary Beth Miller; Julie Muller; Gunter Oberdorster; Elijah J Petersen; Richard C Pleus; Philip Sayre; Vicki Stone; Kristie M Sullivan; Jutta Tentschert; Philip Wallis; Andre E Nel
Journal: ACS Nano Date: 2015-03-20 Impact factor: 15.881

Review 5. Three-dimensional nano-biointerface as a new platform for guiding cell fate.

Authors: Xueli Liu; Shutao Wang
Journal: Chem Soc Rev Date: 2014-02-06 Impact factor: 54.564

6. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

Authors: Yizhou Dong; Kevin T Love; J Robert Dorkin; Sasilada Sirirungruang; Yunlong Zhang; Delai Chen; Roman L Bogorad; Hao Yin; Yi Chen; Arturo J Vegas; Christopher A Alabi; Gaurav Sahay; Karsten T Olejnik; Weiheng Wang; Avi Schroeder; Abigail K R Lytton-Jean; Daniel J Siegwart; Akin Akinc; Carmen Barnes; Scott A Barros; Mary Carioto; Kevin Fitzgerald; Julia Hettinger; Varun Kumar; Tatiana I Novobrantseva; June Qin; William Querbes; Victor Koteliansky; Robert Langer; Daniel G Anderson
Journal: Proc Natl Acad Sci U S A Date: 2014-02-10 Impact factor: 11.205

Accelerating the Translation of Nanomaterials in Biomedicine.

1. Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier.

2. Nano-flares: probes for transfection and mRNA detection in living cells.

3. The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles. Micelles as microcontainers for drug targeting.

4. Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making.

Review 5. Three-dimensional nano-biointerface as a new platform for guiding cell fate.

6. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

Review 7. Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies.

Review 8. Nanocarriers as an emerging platform for cancer therapy.

9. Nanomedicine for glaucoma: liposomes provide sustained release of latanoprost in the eye.

10. A bio-inspired swellable microneedle adhesive for mechanical interlocking with tissue.

1. Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery.

2. Multiple Administrations of Viral Nanoparticles Alter in Vivo Behavior-Insights from Intravital Microscopy.

Review 3. The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction.

4. Nanoparticle transport phenomena in confined flows.

5. Zwitterion and Oligo(ethylene glycol) Synergy Minimizes Nonspecific Binding of Compact Quantum Dots.

6. Protein Mimetic and Anticancer Properties of Monocyte-Targeting Peptide Amphiphile Micelles.

Review 7. Emerging nanotechnologies for cancer immunotherapy.

Review 8. Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines.

9. Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine.

10. Cancer theranostics with ⁶⁴Cu/¹⁷⁷Lu-loaded liposomes.