Literature DB >> 26082453

Lab-on-a-CD: A Fully Integrated Molecular Diagnostic System.

Ling X Kong1, Alexandra Perebikovsky2, Jacob Moebius3, Lawrence Kulinsky4, Marc Madou5.   

Abstract

The field of centrifugal microfluidics has experienced tremendous growth during the past 15 years, especially in applications such as lab-on-a-disc (LoD) diagnostics. The strength of LoD systems lies in its potential for development into fully integrated sample-to-answer analysis systems. This review highlights the technologies necessary to develop the next generation of these systems. In addition to outlining valving and other fluid-handling operations, we discuss the recent advances and future outlook in four categories of LoD processes: reagent storage, sample preparation, nucleic acid amplification, and analyte detection strategies.
© 2015 Society for Laboratory Automation and Screening.

Keywords:  LoD; analytical; assay; centrifugal; microfluidics; point-of-care; sample-to-answer

Mesh：

Year:  2015        PMID： 26082453     DOI： 10.1177/2211068215588456

Source DB:  PubMed          Journal:  J Lab Autom        ISSN： 2211-0682


  15 in total

Review 1.  Point-of-care diagnostics for infectious diseases: From methods to devices.

Authors:  Chao Wang; Mei Liu; Zhifei Wang; Song Li; Yan Deng; Nongyue He
Journal:  Nano Today       Date:  2021-02-06       Impact factor: 20.722

2.  Facile production of quercetin nanoparticles using 3D printed centrifugal flow reactors.

Authors:  Davide De Grandi; Alireza Meghdadi; Gareth LuTheryn; Dario Carugo
Journal:  RSC Adv       Date:  2022-07-19       Impact factor: 4.036

3.  Sample-to-Answer Microfluidic Nucleic Acid Testing (NAT) on Lab-on-a-Disc for Malaria Detection at Point of Need.

Authors:  Gihoon Choi; Weihua Guan
Journal:  Methods Mol Biol       Date:  2022

4.  Determination of red blood cell deformability using centrifugal force in a three-dimensional-printed mini-disk (3D-PMD).

Authors:  Hyunjung Lim; Seung Min Back; Jeonghun Nam; Hyuk Choi
Journal:  PLoS One       Date:  2018-05-22       Impact factor: 3.240

5.  Photochemical Synthesis and Versatile Functionalization Method of a Robust Porous Poly(ethylene glycol methacrylate-co-allyl methacrylate) Monolith Dedicated to Radiochemical Separation in a Centrifugal Microfluidic Platform.

Authors:  Marion Losno; Ivan Ferrante; René Brennetot; Jérôme Varlet; Cécile Blanc; Bernard Grenut; Etienne Amblard; Stéphanie Descroix; Clarisse Mariet
Journal:  Micromachines (Basel)       Date:  2016-03-10       Impact factor: 2.891

Review 6.  CD-Based Microfluidics for Primary Care in Extreme Point-of-Care Settings.

Authors:  Suzanne Smith; Dario Mager; Alexandra Perebikovsky; Ehsan Shamloo; David Kinahan; Rohit Mishra; Saraí M Torres Delgado; Horacio Kido; Satadal Saha; Jens Ducrée; Marc Madou; Kevin Land; Jan G Korvink
Journal:  Micromachines (Basel)       Date:  2016-01-29       Impact factor: 2.891

Review 7.  A Review of Biomedical Centrifugal Microfluidic Platforms.

Authors:  Minghui Tang; Guanghui Wang; Siu-Kai Kong; Ho-Pui Ho
Journal:  Micromachines (Basel)       Date:  2016-02-06       Impact factor: 2.891

8.  Determination of Mercury(II) on A Centrifugal Microfluidic Device Using Ionic Liquid Dispersive Liquid-Liquid Microextraction.

Authors:  Yun Hui; Yujia Liu; William C Tang; Dian Song; Marc Madou; Shanhong Xia; Tianzhun Wu
Journal:  Micromachines (Basel)       Date:  2019-08-08       Impact factor: 2.891

9.  Siphon-Controlled Automation on a Lab-on-a-Disc Using Event-Triggered Dissolvable Film Valves.

Authors:  Brian D Henderson; David J Kinahan; Jeanne Rio; Rohit Mishra; Damien King; Sarai M Torres-Delgado; Dario Mager; Jan G Korvink; Jens Ducrée
Journal:  Biosensors (Basel)       Date:  2021-03-06

10.  Secure Air Traffic Control at the Hub of Multiplexing on the Centrifugo-Pneumatic Lab-on-a-Disc Platform.

Authors:  Jens Ducrée
Journal:  Micromachines (Basel)       Date:  2021-06-15       Impact factor: 2.891
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