Chuanwen Zhou1,2, Qianjun Li1,2, Shushu Huang3, Lu Fan4, Bingjian Wang1,2, Jian Dai5, Xiaoming Tang6. 1. Department of Public Health, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China. 2. Department of Internal Medicine, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China. 3. Department of Internal Medicine, Affiliated Hospital of Nantong University, Nantong, China. 4. Department of Surgery, Northern Jiangsu People's Hospital, Yangzhou, China. 5. Department of Orthopedics Surgery, Huai'an First People's Hospital, Nanjing Medical University, 6 Beijing Road West, 223300, Huai'an, Jiangsu, China. 6. Department of Orthopedics Surgery, Huai'an First People's Hospital, Nanjing Medical University, 6 Beijing Road West, 223300, Huai'an, Jiangsu, China. xiaomingtang2010@163.com.
Abstract
PURPOSE: To translate quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-31) into a simplified Chinese version, and test its reliability and validity in osteoporosis patients from mainland Chinese population. METHODS: Postmenopausal osteoporosis women with history of vertebral fracture were included as cases, and age-matched healthy female were included as controls. All subjects were from mainland China. The simplified Chinese version of QUALEFFO-31 and SF-36 were assigned to the two groups. Reliability was assessed using kappa statistics of agreement for each item and the intra-class correlation coefficient (ICC). The internal consistency was assessed with Cronbach's α. Pearson's correlation was used to assess convergent and discriminant validity. RESULTS: Overall, 66 cases and 66 age-matched controls were included. The ICC for the test-retest reliability ranged from 0.76 to 0.91. Cronbach's α for pain, physical function, and mental function domains were 0.94, 0.87, and 0.79, respectively. Convergent validity and discriminant validity showed that each correlation coefficient between score of each item with total score of related domain was higher than that with total score of unrelated domain. Pearson's correlation coefficients indicated significantly high correlations between corresponding domains of QUALEFFO-31 and SF-36. CONCLUSIONS: The simplified Chinese version of the QUALEFFO-31 is a reliable and valid outcome measure of functional status in patients with osteoporosis. This Chinese version of the QUALEFFO-31 can be utilized for future clinical studies in mainland China.
PURPOSE: To translate quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-31) into a simplified Chinese version, and test its reliability and validity in osteoporosispatients from mainland Chinese population. METHODS: Postmenopausal osteoporosiswomen with history of vertebral fracture were included as cases, and age-matched healthy female were included as controls. All subjects were from mainland China. The simplified Chinese version of QUALEFFO-31 and SF-36 were assigned to the two groups. Reliability was assessed using kappa statistics of agreement for each item and the intra-class correlation coefficient (ICC). The internal consistency was assessed with Cronbach's α. Pearson's correlation was used to assess convergent and discriminant validity. RESULTS: Overall, 66 cases and 66 age-matched controls were included. The ICC for the test-retest reliability ranged from 0.76 to 0.91. Cronbach's α for pain, physical function, and mental function domains were 0.94, 0.87, and 0.79, respectively. Convergent validity and discriminant validity showed that each correlation coefficient between score of each item with total score of related domain was higher than that with total score of unrelated domain. Pearson's correlation coefficients indicated significantly high correlations between corresponding domains of QUALEFFO-31 and SF-36. CONCLUSIONS: The simplified Chinese version of the QUALEFFO-31 is a reliable and valid outcome measure of functional status in patients with osteoporosis. This Chinese version of the QUALEFFO-31 can be utilized for future clinical studies in mainland China.
Entities:
Keywords:
Osteoporosis; Quality of life; Questionnaires; Validation
Authors: P Lips; C Cooper; D Agnusdei; F Caulin; P Egger; O Johnell; J A Kanis; S Kellingray; A Leplege; U A Liberman; E McCloskey; H Minne; J Reeve; J Y Reginster; M Scholz; C Todd; M C de Vernejoul; I Wiklund Journal: Osteoporos Int Date: 1999 Impact factor: 4.507
Authors: W Cockerill; M Lunt; A J Silman; C Cooper; P Lips; A K Bhalla; J B Cannata; R Eastell; D Felsenberg; C Gennari; O Johnell; J A Kanis; C Kiss; P Masaryk; M Naves; G Poor; H Raspe; D M Reid; J Reeve; J Stepan; C Todd; A D Woolf; T W O'Neill Journal: Osteoporos Int Date: 2003-11-13 Impact factor: 4.507