| Literature DB >> 26066512 |
Dillon H Miles1,2, Joan Guasch1,2, F Dean Toste1,2.
Abstract
The enantioselective addition of anilines to azoalkenes was accomplished through the use of a chiral phosphoric acid catalyst. The resulting α-arylamino hydrazones were obtained in good yields and excellent enantioselectivities and provide access to enantioenriched α-arylamino ketones. A serendipitous kinetic resolution of racemic α-arylamino hydrazones is also described.Entities:
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Year: 2015 PMID: 26066512 PMCID: PMC5152760 DOI: 10.1021/jacs.5b04518
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419