Literature DB >> 26057686

"Getting off the Bus Closer to Your Destination": Patients' Views about Pharmacogenetic Testing.

Susan Brown Trinidad1, Tara B Coffin2, Stephanie M Fullerton3, James Ralston4, Gail P Jarvik5, Eric B Larson6.   

Abstract

The authors conducted focus groups with patients prescribed antidepressants (pilot session plus 2 focus groups, n = 27); patients prescribed carbamazepine (2 focus groups, n = 17); and healthy patients (2 focus groups, n = 17). Although participants understood the potential advantages of pharmacogenetic testing, many felt that the risks (discrimination, stigmatization, physician overreliance on genomic results, and denial of certain medications) may outweigh the benefits. These concerns were shared across groups but were more strongly expressed among participants with chronic mental health diagnoses.

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Year:  2015        PMID: 26057686      PMCID: PMC4500477          DOI: 10.7812/TPP/15-046

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  31 in total

1.  Drug reactions enzymes, and biochemical genetics.

Authors:  A G MOTULSKY
Journal:  J Am Med Assoc       Date:  1957-10-19

2.  Consumers' views of pharmacogenetics--A qualitative study.

Authors:  Catherine A Haddy; Helena M Ward; Manya T Angley; Ross A McKinnon
Journal:  Res Social Adm Pharm       Date:  2010-09

3.  The path to personalized medicine.

Authors:  Margaret A Hamburg; Francis S Collins
Journal:  N Engl J Med       Date:  2010-06-15       Impact factor: 91.245

Review 4.  Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.

Authors:  Jian-Ping Zhang; Anil K Malhotra
Journal:  Expert Opin Drug Metab Toxicol       Date:  2011-01       Impact factor: 4.481

5.  The triple aim: care, health, and cost.

Authors:  Donald M Berwick; Thomas W Nolan; John Whittington
Journal:  Health Aff (Millwood)       Date:  2008 May-Jun       Impact factor: 6.301

6.  Clinical and ethical considerations in pharmacogenetic testing: views of physicians in 3 "early adopting" departments of psychiatry.

Authors:  Jinger G Hoop; Maria I Lapid; Rene M Paulson; Laura Weiss Roberts
Journal:  J Clin Psychiatry       Date:  2010-03-09       Impact factor: 4.384

7.  The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies.

Authors:  Catherine A McCarty; Rex L Chisholm; Christopher G Chute; Iftikhar J Kullo; Gail P Jarvik; Eric B Larson; Rongling Li; Daniel R Masys; Marylyn D Ritchie; Dan M Roden; Jeffery P Struewing; Wendy A Wolf
Journal:  BMC Med Genomics       Date:  2011-01-26       Impact factor: 3.063

Review 8.  Evolving approaches to the ethical management of genomic data.

Authors:  Jean E McEwen; Joy T Boyer; Kathie Y Sun
Journal:  Trends Genet       Date:  2013-02-28       Impact factor: 11.639

9.  Patients' and healthcare professionals' views on pharmacogenetic testing and its future delivery in the NHS.

Authors:  Emily A Fargher; Charlotte Eddy; William Newman; Faieza Qasim; Karen Tricker; Rachel A Elliott; Katherine Payne
Journal:  Pharmacogenomics       Date:  2007-11       Impact factor: 2.533

Review 10.  Implementing genomic medicine in the clinic: the future is here.

Authors:  Teri A Manolio; Rex L Chisholm; Brad Ozenberger; Dan M Roden; Marc S Williams; Richard Wilson; David Bick; Erwin P Bottinger; Murray H Brilliant; Charis Eng; Kelly A Frazer; Bruce Korf; David H Ledbetter; James R Lupski; Clay Marsh; David Mrazek; Michael F Murray; Peter H O'Donnell; Daniel J Rader; Mary V Relling; Alan R Shuldiner; David Valle; Richard Weinshilboum; Eric D Green; Geoffrey S Ginsburg
Journal:  Genet Med       Date:  2013-01-10       Impact factor: 8.822

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  6 in total

1.  Patient experiences with pharmacogenetic testing in a primary care setting.

Authors:  Susanne B Haga; Rachel Mills; Jivan Moaddeb; Nancy Allen Lapointe; Alex Cho; Geoffrey S Ginsburg
Journal:  Pharmacogenomics       Date:  2016-09-20       Impact factor: 2.533

2.  Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine.

Authors:  Lejla Mahmutovic; Betul Akcesme; Camil Durakovic; Faruk Berat Akcesme; Aida Maric; Muhamed Adilovic; Nour Hamad; Matthias Wjst; Oliver Feeney; Sabina Semiz
Journal:  Hum Genomics       Date:  2018-11-14       Impact factor: 4.639

Review 3.  Pharmacogenomic Testing: Clinical Evidence and Implementation Challenges.

Authors:  Catriona Hippman; Corey Nislow
Journal:  J Pers Med       Date:  2019-08-07

4.  Patients' Perceptions of Pharmacogenetic Testing and Access to Their Results: State of the Art in Spain and Systematic Review.

Authors:  Pablo Zubiaur; David Nicolás Prósper-Cuesta; Jesús Novalbos; Gina Mejía-Abril; Marcos Navares-Gómez; Gonzalo Villapalos-García; Paula Soria-Chacartegui; Francisco Abad-Santos
Journal:  J Pers Med       Date:  2022-02-12

5.  Lay understandings of drug-gene interactions: The right medication, the right dose, at the right time, but what are the right words?

Authors:  Karen M Meagher; Kelsey Stuttgen Finn; Susan H Curtis; Jack Borucki; Annika T Beck; Amal W Cheema; Richard R Sharp
Journal:  Clin Transl Sci       Date:  2021-11-25       Impact factor: 4.689

Review 6.  A Scoping Review of Attitudes and Experiences with Pharmacogenomic Testing among Patients and the General Public: Implications for Patient Counseling.

Authors:  Josiah D Allen; Amy L Pittenger; Jeffrey R Bishop
Journal:  J Pers Med       Date:  2022-03-09
  6 in total

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