| Literature DB >> 26052157 |
C Kuhlmann1, A P Khandhar2, R M Ferguson3, S Kemp3, T Wawrzik1, M Schilling1, K M Krishnan4, F Ludwig1.
Abstract
The drive-field frequency of Magnetic Particle Imaging (MPI) systems plays an important role for system design, safety requirements and tracer selection. Because the commonly utilized MPI drive-field frequency of 25 kHz might be increased in future system generations to avoid peripheral nerve stimulation, a performance evaluation of tracers at higher frequencies is desirable. We have studied single-core magnetite nanoparticles that were optimized for MPI applications, utilizing Magnetic Particle Spectrometers (MPS) with drive-field frequencies in the range from 1 kHz up to 100 kHz. The particles have core diameters of 25 nm and a hydrodynamic size of 77 nm. Measurements in the frequency range above 5 kHz were carried out with a newly designed MPS system. In addition, to exclude possible particle interaction, samples of different concentrations were characterized and compared.Entities:
Keywords: Magnetic particle imaging; magnetic particle spectroscopy; magnetic particles; tracer performance
Year: 2015 PMID： 26052157 PMCID： PMC4454424 DOI： 10.1109/TMAG.2014.2329772
Source DB: PubMed Journal: IEEE Trans Magn ISSN： 0018-9464 Impact factor: 1.700