Literature DB >> 26047767

The Evolving Role of the Laboratory Professional in the Age of Genome Sequencing: A Vision of the Association for Molecular Pathology.

Iris Schrijver1, Daniel H Farkas2, Jane S Gibson3, Elaine Lyon4.   

Abstract

In conclusion, to maximize the benefit of the genomic era, the molecular laboratory director will continue to be essential in the generation, analysis, and interpretation of patient results, which now include genomic data obtained through NGS approaches. That includes integrating this information as part of the complete care of the patient and communicating and interacting with professionals across disciplines. In addition, the molecular laboratory director must continue to provide training and education to current and future colleagues, within and outside of molecular pathology and molecular genetics. Professionalism includes volunteerism in professional organizations and education and advocacy to policy makers, health administrators, payers, and the public. It also includes efforts to increase visibility of the profession to our colleagues from other medical disciplines and the public at large. Thus, the role of the molecular laboratory professional is multifaceted, but, above all, it is to ensure the access to and quality of molecular pathology testing, the responsible implementation of expanded test modalities such as genome sequencing, and the interpretation thereof to aid the clinician in the medical management of the patient and ultimately to benefit the society by providing precision patient care.
Copyright © 2015 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26047767     DOI: 10.1016/j.jmoldx.2015.03.001

Source DB:  PubMed          Journal:  J Mol Diagn        ISSN: 1525-1578            Impact factor:   5.568


  5 in total

1.  Evaluation of Commercial Next-Generation Sequencing Bioinformatics Software Solutions.

Authors:  Rama R Gullapalli
Journal:  J Mol Diagn       Date:  2019-11-18       Impact factor: 5.568

Review 2.  Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists.

Authors:  Marilyn M Li; Michael Datto; Eric J Duncavage; Shashikant Kulkarni; Neal I Lindeman; Somak Roy; Apostolia M Tsimberidou; Cindy L Vnencak-Jones; Daynna J Wolff; Anas Younes; Marina N Nikiforova
Journal:  J Mol Diagn       Date:  2017-01       Impact factor: 5.568

Review 3.  Defining the Clinical Value of a Genomic Diagnosis in the Era of Next-Generation Sequencing.

Authors:  Natasha T Strande; Jonathan S Berg
Journal:  Annu Rev Genomics Hum Genet       Date:  2016-05-26       Impact factor: 8.929

Review 4.  Navigating the nuances of clinical sequence variant interpretation in Mendelian disease.

Authors:  Natasha T Strande; Sarah E Brnich; Tamara S Roman; Jonathan S Berg
Journal:  Genet Med       Date:  2018-07-10       Impact factor: 8.822

5.  Defining current gaps in quality measures for cancer immunotherapy: consensus report from the Society for Immunotherapy of Cancer (SITC) 2019 Quality Summit.

Authors:  Sara Pai; David Blaisdell; Rachel Brodie; Robert Carlson; Heidi Finnes; Michele Galioto; Roxanne E Jensen; Tom Valuck; Antonia R Sepulveda; Howard L Kaufman
Journal:  J Immunother Cancer       Date:  2020-01       Impact factor: 13.751

  5 in total

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