Literature DB >> 26046445

SnapShot: Spliceosome Dynamics I.

Markus C Wahl1, Reinhard Lührmann2.   

Abstract

Spliceosomes are multi-megadalton RNA-protein molecular machines that carry out pre-mRNA splicing, that is, the removal of non-coding intervening sequences (introns) from eukaryotic pre-mRNAs and the ligation of neighboring coding regions (exons) to produce mature mRNA for protein biosynthesis on the ribosome. They are the prototypes of dynamic molecular machines, assembling de novo for each splicing event by the stepwise recruitment of subunits on a substrate.
Copyright © 2015 Elsevier Inc. All rights reserved.

Mesh：

Year:  2015        PMID： 26046445     DOI： 10.1016/j.cell.2015.05.050

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  29 in total

Review 1.  The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.

Authors:  Elisabeth Daguenet; Gwendal Dujardin; Juan Valcárcel
Journal:  EMBO Rep       Date:  2015-11-13       Impact factor: 8.807

Review 2.  Functions and regulation of the Brr2 RNA helicase during splicing.

Authors:  Eva Absmeier; Karine F Santos; Markus C Wahl
Journal:  Cell Cycle       Date:  2016-10-28       Impact factor: 4.534

Review 3.  mRNA Editing, Processing and Quality Control in Caenorhabditis elegans.

Authors:  Joshua A Arribere; Hidehito Kuroyanagi; Heather A Hundley
Journal:  Genetics       Date:  2020-07       Impact factor: 4.562

4.  Coupling of spliceosome complexity to intron diversity.

Authors:  Jade Sales-Lee; Daniela S Perry; Bradley A Bowser; Jolene K Diedrich; Beiduo Rao; Irene Beusch; John R Yates; Scott W Roy; Hiten D Madhani
Journal:  Curr Biol       Date:  2021-09-22       Impact factor: 10.834

5.  Aberrant RNA Splicing in Cancer.

Authors:  Luisa Escobar-Hoyos; Katherine Knorr; Omar Abdel-Wahab
Journal:  Annu Rev Cancer Biol       Date:  2018-11-28

6.  U5 snRNA Interactions With Exons Ensure Splicing Precision.

Authors:  Olga V Artemyeva-Isman; Andrew C G Porter
Journal:  Front Genet       Date:  2021-07-02       Impact factor: 4.599

Review 7.  Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics.

Authors:  Laura M Urbanski; Nathan Leclair; Olga Anczuków
Journal:  Wiley Interdiscip Rev RNA       Date:  2018-04-25       Impact factor: 9.957

8.  A genetic screen for temperature-sensitive morphogenesis-defective Caenorhabditis elegans mutants.

Authors:  Molly C Jud; Josh Lowry; Thalia Padilla; Erin Clifford; Yuqi Yang; Francesca Fennell; Alexander K Miller; Danielle Hamill; Austin M Harvey; Martha Avila-Zavala; Hong Shao; Nhan Nguyen Tran; Zhirong Bao; Bruce Bowerman
Journal:  G3 (Bethesda)       Date:  2021-04-15       Impact factor: 3.154

Review 9.  Evolutionary Insights into RNA trans-Splicing in Vertebrates.

Authors:  Quan Lei; Cong Li; Zhixiang Zuo; Chunhua Huang; Hanhua Cheng; Rongjia Zhou
Journal:  Genome Biol Evol       Date:  2016-03-10       Impact factor: 3.416

Review 10.  Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis.

Authors:  Daichi Inoue; Robert K Bradley; Omar Abdel-Wahab
Journal:  Genes Dev       Date:  2016-05-01       Impact factor: 11.361
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