Literature DB >> 26045348

Duration of untreated psychosis and need for admission in patients who engage with mental health services in the prodromal phase.

Lucia R Valmaggia1,2, Majella Byrne1,2, Fern Day1, Matthew R Broome3, Louise Johns1, Oliver Howes1, Paddy Power4, Steven Badger2, Paolo Fusar-Poli1,2, Philip K McGuire1,2.   

Abstract

BACKGROUND: It is unknown whether prodromal services improve outcomes in those who go on to develop psychosis, and whether these patients are demographically different from the overall first-episode population. AIMS: To compare sociodemographic features, duration of untreated psychosis, hospital admission and frequency of compulsory treatment in the first year after the onset of psychosis in patients who present to prodromal services with patients who did not present to services until the first episode of psychosis.
METHOD: We compared two groups of patients with first-episode psychosis: one who made transition after presenting in the prodromal phase and the other who had presented with a first episode.
RESULTS: The patients who had presented before the first episode were more likely to be employed and less likely to belong to an ethnic minority group. They had a shorter duration of untreated psychosis, and were less likely to have been admitted to hospital and to have required compulsory treatment.
CONCLUSIONS: Patients who develop psychosis after being engaged in the prodromal phase have a better short-term clinical outcome than patients who do not present until the first episode. Patients who present during first episodes may be more likely to have sociodemographic features associated with relatively poor outcomes. © The Royal College of Psychiatrists 2015.

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Year:  2015        PMID: 26045348      PMCID: PMC4655441          DOI: 10.1192/bjp.bp.114.150623

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  25 in total

1.  Causes and consequences of duration of untreated psychosis in schizophrenia.

Authors:  R J Drake; C J Haley; S Akhtar; S W Lewis
Journal:  Br J Psychiatry       Date:  2000-12       Impact factor: 9.319

2.  Duration of untreated psychosis and cognitive functioning in first-episode patients.

Authors:  R M Norman; L Townsend; A K Malla
Journal:  Br J Psychiatry       Date:  2001-10       Impact factor: 9.319

3.  Transition to schizophrenia in acute and transient psychotic disorders.

Authors:  Filippo Queirazza; David M Semple; Stephen M Lawrie
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4.  The impact of delivering GP training on the clinical high risk and first-episode psychosis on referrals and pathways to care.

Authors:  Nicky Reynolds; Philippe Wuyts; Steven Badger; Paolo Fusar-Poli; Philip McGuire; Lucia Valmaggia
Journal:  Early Interv Psychiatry       Date:  2014-03-06       Impact factor: 2.732

5.  Identification of young people at risk of psychosis: validation of Personal Assessment and Crisis Evaluation Clinic intake criteria.

Authors:  L J Phillips; A R Yung; P D McGorry
Journal:  Aust N Z J Psychiatry       Date:  2000-11       Impact factor: 5.744

Review 6.  At risk for schizophrenic or affective psychoses? A meta-analysis of DSM/ICD diagnostic outcomes in individuals at high clinical risk.

Authors:  Paolo Fusar-Poli; Andreas Bechdolf; Matthew John Taylor; Ilaria Bonoldi; William T Carpenter; Alison Ruth Yung; Philip McGuire
Journal:  Schizophr Bull       Date:  2012-05-15       Impact factor: 9.306

7.  Outreach and support in south London (OASIS), 2001-2011: ten years of early diagnosis and treatment for young individuals at high clinical risk for psychosis.

Authors:  P Fusar-Poli; M Byrne; S Badger; L R Valmaggia; P K McGuire
Journal:  Eur Psychiatry       Date:  2012-11-06       Impact factor: 5.361

8.  Cannabis use and transition to psychosis in people at ultra-high risk.

Authors:  L R Valmaggia; F L Day; C Jones; S Bissoli; C Pugh; D Hall; S Bhattacharyya; O Howes; J Stone; P Fusar-Poli; M Byrne; P K McGuire
Journal:  Psychol Med       Date:  2014-09       Impact factor: 7.723

9.  Reappraising the long-term course and outcome of psychotic disorders: the AESOP-10 study.

Authors:  C Morgan; J Lappin; M Heslin; K Donoghue; B Lomas; U Reininghaus; A Onyejiaka; T Croudace; P B Jones; R M Murray; P Fearon; G A Doody; P Dazzan
Journal:  Psychol Med       Date:  2014-02-26       Impact factor: 7.723

Review 10.  A meta-analysis of ethnic differences in pathways to care at the first episode of psychosis.

Authors:  K K Anderson; N Flora; S Archie; C Morgan; K McKenzie
Journal:  Acta Psychiatr Scand       Date:  2014-02-28       Impact factor: 6.392

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  19 in total

Review 1.  Maximizing response to first-line antipsychotics in schizophrenia: a review focused on finding from meta-analysis.

Authors:  Robert C Smith; Stefan Leucht; John M Davis
Journal:  Psychopharmacology (Berl)       Date:  2018-11-30       Impact factor: 4.530

2.  Beyond the "at risk mental state" concept: transitioning to transdiagnostic psychiatry.

Authors:  Patrick D McGorry; Jessica A Hartmann; Rachael Spooner; Barnaby Nelson
Journal:  World Psychiatry       Date:  2018-06       Impact factor: 49.548

3.  Why ultra high risk criteria for psychosis prediction do not work well outside clinical samples and what to do about it.

Authors:  Paolo Fusar-Poli
Journal:  World Psychiatry       Date:  2017-06       Impact factor: 49.548

4.  Treatment of people at ultra-high risk for psychosis.

Authors:  Alison R Yung
Journal:  World Psychiatry       Date:  2017-06       Impact factor: 49.548

5.  Medication adherence in first episode psychosis: the role of pre-onset subthreshold symptoms.

Authors:  J-G Daneault; A Maraj; M Lepage; A Malla; N Schmitz; S N Iyer; R Joober; J L Shah
Journal:  Acta Psychiatr Scand       Date:  2019-04       Impact factor: 6.392

6.  Psychosis as a continuous phenotype in the general population: the thin line between normality and pathology.

Authors:  Anthony S David; Olesya Ajnakina
Journal:  World Psychiatry       Date:  2016-06       Impact factor: 49.548

7.  Improving outcomes of first-episode psychosis: an overview.

Authors:  Paolo Fusar-Poli; Patrick D McGorry; John M Kane
Journal:  World Psychiatry       Date:  2017-10       Impact factor: 49.548

8.  Duration of the psychosis prodrome.

Authors:  Albert R Powers; Jean Addington; Diana O Perkins; Carrie E Bearden; Kristin S Cadenhead; Tyrone D Cannon; Barbara A Cornblatt; Daniel H Mathalon; Larry J Seidman; Ming T Tsuang; Elaine F Walker; Thomas H McGlashan; Scott W Woods
Journal:  Schizophr Res       Date:  2019-12-02       Impact factor: 4.939

9.  Development and Validation of a Clinically Based Risk Calculator for the Transdiagnostic Prediction of Psychosis.

Authors:  Paolo Fusar-Poli; Grazia Rutigliano; Daniel Stahl; Cathy Davies; Ilaria Bonoldi; Thomas Reilly; Philip McGuire
Journal:  JAMA Psychiatry       Date:  2017-05-01       Impact factor: 21.596

10.  Predictive validity of conversion from the clinical high risk syndrome to frank psychosis.

Authors:  Laura A Yoviene Sykes; Maria Ferrara; Jean Addington; Carrie E Bearden; Kristin S Cadenhead; Tyrone D Cannon; Barbara A Cornblatt; Diana O Perkins; Daniel H Mathalon; Larry J Seidman; Ming T Tsuang; Elaine F Walker; Thomas H McGlashan; Kristen A Woodberry; Albert R Powers; Allison N Ponce; John D Cahill; Jessica M Pollard; Vinod H Srihari; Scott W Woods
Journal:  Schizophr Res       Date:  2019-12-19       Impact factor: 4.939

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