Literature DB >> 26035325

Soluble CD14 is a nonspecific marker of monocyte activation.

Carey L Shive1, Wei Jiang, Donald D Anthony, Michael M Lederman.   

Abstract

Soluble CD14 is associated with morbidity and mortality in HIV disease. It is a co-receptor for lipopolysaccharide (LPS) that is released from monocytes upon activation. We demonstrate here, that inflammatory cytokines can induce the release of sCD14 in peripheral blood mononuclear cell cultures from healthy donors, and that TLR ligands other than LPS can cause a decrease in the monocyte cell surface expression of CD14. Thus, sCD14 is a marker of monocyte activation, not restricted to activation by LPS.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26035325      PMCID： PMC4452959          DOI： 10.1097/QAD.0000000000000735

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  23 in total

1.  Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection.

Authors:  Peter W Hunt; Elizabeth Sinclair; Benigno Rodriguez; Carey Shive; Brian Clagett; Nicholas Funderburg; Janet Robinson; Yong Huang; Lorrie Epling; Jeffrey N Martin; Steven G Deeks; Curtis L Meinert; Mark L Van Natta; Douglas A Jabs; Michael M Lederman
Journal:  J Infect Dis       Date:  2014-04-21       Impact factor: 5.226

Review 2.  Modulatory effects of sCD14 and LBP on LPS-host cell interactions.

Authors:  Richard L Kitchens; Patricia A Thompson
Journal:  J Endotoxin Res       Date:  2005

3.  Elevated soluble CD14 receptors and altered cytokines in chronic heart failure.

Authors:  S D Anker; K R Egerer; H D Volk; W J Kox; P A Poole-Wilson; A J Coats
Journal:  Am J Cardiol       Date:  1997-05-15       Impact factor: 2.778

4.  Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.

Authors:  Allan R Tenorio; Yu Zheng; Ronald J Bosch; Supriya Krishnan; Benigno Rodriguez; Peter W Hunt; Jill Plants; Arjun Seth; Cara C Wilson; Steven G Deeks; Michael M Lederman; Alan L Landay
Journal:  J Infect Dis       Date:  2014-05-01       Impact factor: 5.226

5.  Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide.

Authors:  P Y Wang; R L Kitchens; R S Munford
Journal:  J Biol Chem       Date:  1998-09-18       Impact factor: 5.157

6.  Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.

Authors:  E Lien; P Aukrust; A Sundan; F Müller; S S Frøland; T Espevik
Journal:  Blood       Date:  1998-09-15       Impact factor: 22.113

7.  Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.

Authors:  B Yu; E Hailman; S D Wright
Journal:  J Clin Invest       Date:  1997-01-15       Impact factor: 14.808

8.  CD14 is a pattern recognition receptor.

Authors:  J Pugin; I D Heumann; A Tomasz; V V Kravchenko; Y Akamatsu; M Nishijima; M P Glauser; P S Tobias; R J Ulevitch
Journal:  Immunity       Date:  1994-09       Impact factor: 31.745

9.  Soluble lipopolysaccharide receptor (CD14) is released via two different mechanisms from human monocytes and CD14 transfectants.

Authors:  P Bufler; G Stiegler; M Schuchmann; S Hess; C Krüger; F Stelter; C Eckerskorn; C Schütt; H Engelmann
Journal:  Eur J Immunol       Date:  1995-02       Impact factor: 5.532

10.  Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Authors:  Jason M Brenchley; David A Price; Timothy W Schacker; Tedi E Asher; Guido Silvestri; Srinivas Rao; Zachary Kazzaz; Ethan Bornstein; Olivier Lambotte; Daniel Altmann; Bruce R Blazar; Benigno Rodriguez; Leia Teixeira-Johnson; Alan Landay; Jeffrey N Martin; Frederick M Hecht; Louis J Picker; Michael M Lederman; Steven G Deeks; Daniel C Douek
Journal:  Nat Med       Date:  2006-11-19       Impact factor: 53.440
View more
  92 in total

1.  CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection.

Authors:  Michael L Freeman; Joseph C Mudd; Carey L Shive; Souheil-Antoine Younes; Soumya Panigrahi; Scott F Sieg; Sulggi A Lee; Peter W Hunt; Leonard H Calabrese; Sara Gianella; Benigno Rodriguez; Michael M Lederman
Journal:  Clin Infect Dis       Date:  2015-09-23       Impact factor: 9.079

Review 2.  Serious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection.

Authors:  Denise C Hsu; Irini Sereti
Journal:  Drugs       Date:  2016-04       Impact factor: 9.546

3.  Elevated systemic microbial translocation in pregnant HIV-infected women compared to HIV-uninfected women, and its inverse correlations with plasma progesterone levels.

Authors:  Zejun Zhou; Anna Maya Powell; Vishwanathan Ramakrishnan; Allison Eckard; Carol Wagner; Wei Jiang
Journal:  J Reprod Immunol       Date:  2018-04-10       Impact factor: 4.054

4.  Alcohol use predicts elevation in inflammatory marker soluble CD14 in men living with HIV.

Authors:  Mollie A Monnig; Christopher W Kahler; Patricia A Cioe; Lynne Tucker; Peter M Monti; Kenneth H Mayer; Bharat Ramratnam
Journal:  AIDS Care       Date:  2016-05-30

5.  Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation.

Authors:  Diana V Avila; Scott A Myers; JingWen Zhang; Giorgi Kharebava; Craig J McClain; Hee-Yong Kim; Scott R Whittemore; Leila Gobejishvili; Shirish Barve
Journal:  Neuropharmacology       Date:  2017-08-12       Impact factor: 5.250

6.  Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

Authors:  Aida Sivro; Alexandra Schuetz; Daniel Sheward; Vineet Joag; Sergey Yegorov; Lenine J Liebenberg; Nonhlanhla Yende-Zuma; Andrew Stalker; Ruth S Mwatelah; Philippe Selhorst; Nigel Garrett; Natasha Samsunder; Anisha Balgobin; Fatima Nawaz; Claudia Cicala; James Arthos; Anthony S Fauci; Aggrey Omu Anzala; Joshua Kimani; Bernard S Bagaya; Noah Kiwanuka; Carolyn Williamson; Rupert Kaul; Jo-Ann S Passmore; Nittaya Phanuphak; Jintanat Ananworanich; Aftab Ansari; Quarraisha Abdool Karim; Salim S Abdool Karim; Lyle R McKinnon
Journal:  Sci Transl Med       Date:  2018-01-24       Impact factor: 17.956

7.  Substance-associated elevations in monocyte activation among methamphetamine users with treated HIV infection.

Authors:  Adam W Carrico; Emily M Cherenack; Margaret E Roach; Elise D Riley; Olorunleke Oni; Samantha E Dilworth; Steven Shoptaw; Peter Hunt; Sabita Roy; Suresh Pallikkuth; Savita Pahwa
Journal:  AIDS       Date:  2018-03-27       Impact factor: 4.177

8.  The effects of probiotic supplementation on the gene expressions of immune cell surface markers and levels of antibodies and pro-inflammatory cytokines in human milk.

Authors:  Veronique Demers-Mathieu; Gabrielle B Mathijssen; Ciera DaPra; Elena Medo
Journal:  J Perinatol       Date:  2020-11-18       Impact factor: 2.521

Review 9.  Role of immune activation in progression to AIDS.

Authors:  Netanya S Utay; Peter W Hunt
Journal:  Curr Opin HIV AIDS       Date:  2016-03       Impact factor: 4.283

10.  Novel relationships of markers of monocyte activation and endothelial dysfunction with pulmonary dysfunction in HIV-infected persons.

Authors:  Meghan E Fitzpatrick; Mehdi Nouraie; Matthew R Gingo; Danielle Camp; Cathy J Kessinger; James B Sincebaugh; Andrew Clarke; John W Ries; Eric C Kleerup; Lawrence Kingsley; Alison Morris
Journal:  AIDS       Date:  2016-06-01       Impact factor: 4.177
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.