Literature DB >> 9165177

Elevated soluble CD14 receptors and altered cytokines in chronic heart failure.

S D Anker1, K R Egerer, H D Volk, W J Kox, P A Poole-Wilson, A J Coats.   

Abstract

We hypothesized that in patients with chronic heart failure mesenteric venous congestion leads to increased bowel permeability, bacterial translocation, and thereby endotoxin release; the increased endotoxin challenge then causes immune activation with increased soluble CD14 levels and tumor necrosis factor (TNF)-alpha production. Patients with high soluble CD14 levels (indicative of endotoxin-cell interaction) have markedly increased plasma levels of TNF-alpha, soluble TNF receptors 1 and 2, and intracellular adhesion molecule-1, supporting this hypothesis.

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Year:  1997        PMID： 9165177     DOI： 10.1016/s0002-9149(97)00159-8

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  66 in total

Review 1.  Activation of cytokines as a mechanism of disease progression in heart failure.

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Journal:  Ann Rheum Dis       Date:  2000-11       Impact factor: 19.103

Review 2.  Statins and the role of nitric oxide in chronic heart failure.

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3.  Inflammatory mediators in chronic heart failure: an overview.

Authors:  Stefan D Anker; Stephan von Haehling
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4.  Circulating endotoxemia: a novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease.

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Review 5.  [Percutaneous aortic valve replacement - pro].

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Review 6.  Tumour necrosis factor in chronic heart failure: a peripheral view on pathogenesis, clinical manifestations and therapeutic implications.

Authors:  A P Bolger; S D Anker
Journal:  Drugs       Date:  2000-12       Impact factor: 9.546

7.  Soluble CD14 is a nonspecific marker of monocyte activation.

Authors:  Carey L Shive; Wei Jiang; Donald D Anthony; Michael M Lederman
Journal:  AIDS       Date:  2015-06-19       Impact factor: 4.177

8.  Gut microbiota, endotoxemia, inflammation, and oxidative stress in patients with heart failure, left ventricular assist device, and transplant.

Authors:  Melana Yuzefpolskaya; Bruno Bohn; Mojdeh Nasiri; Amelia M Zuver; Drew D Onat; Eugene A Royzman; Joseph Nwokocha; Melissa Mabasa; Alberto Pinsino; Danielle Brunjes; Antonia Gaudig; Autumn Clemons; Pauline Trinh; Stephania Stump; Marla J Giddins; Veli K Topkara; A Reshad Garan; Koji Takeda; Hiroo Takayama; Yoshifumi Naka; Maryjane A Farr; Renu Nandakumar; Anne-Catrin Uhlemann; Paolo C Colombo; Ryan T Demmer
Journal:  J Heart Lung Transplant       Date:  2020-02-13       Impact factor: 10.247

Review 9.  Right Heart Failure and Cardiorenal Syndrome.

Authors:  Thida Tabucanon; Wai Hong Wilson Tang
Journal:  Cardiol Clin       Date:  2020-03-02       Impact factor: 2.213

10.  Investigation of novel LPS-induced differentially expressed long non-coding RNAs in endothelial cells.

Authors:  Krishna K Singh; Pratiek N Matkar; Shoaib Muhammad; Adrian Quan; Vijay Gupta; Hwee Teoh; Mohammed Al-Omran; Subodh Verma
Journal:  Mol Cell Biochem       Date:  2016-08-26       Impact factor: 3.396
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