Literature DB >> 26032136

Geriatric Assessment of Older Adults With Cancer During Unplanned Hospitalizations: An Opportunity in Disguise.

Caroline Mariano1, Grant Williams2, Allison Deal2, Shani Alston2, Ashley Leak Bryant2, Trevor Jolly2, Hyman B Muss2.   

Abstract

BACKGROUND: Geriatric assessment (GA) is an important tool for management of older cancer patients; however, GA research has been performed primarily in the outpatient setting. The primary objective of this study was to determine feasibility of GA during an unplanned hospital stay. Secondary objectives were to describe deficits found with GA, to assess whether clinicians recognized and addressed deficits, and to determine 30-day readmission rates.
MATERIALS AND METHODS: The study was designed as an extension of an existing registry, "Carolina Senior: Registry for Older Patients." Inclusion criteria were age 70 and older and biopsy-proven solid tumor, myeloma, or lymphoma. Patients had to complete the GA within 7 days of nonelective admission to University of North Carolina Hospital.
RESULTS: A total of 142 patients were approached, and 90 (63%) consented to participation. All sections of GA had at least an 83% completion rate. Overall, 53% of patients reported problems with physical function, 63% had deficits in instrumental activities of daily living, 34% reported falls, 12% reported depression, 31% had ≥10% weight loss, and 12% had abnormalities in cognition. Physician documentation of each deficit ranged from 20% to 46%. Rates of referrals to allied health professionals were not significantly different between patients with and without deficits. The 30-day readmission rate was 29%.
CONCLUSION: GA was feasible in this population. Hospitalized older cancer patients have high levels of functional and psychosocial deficits; however, clinician recognition and management of deficits were poor. The use of GA instruments to guide referrals to appropriate services is a way to potentially improve outcomes in this vulnerable population. IMPLICATIONS FOR PRACTICE: Geriatric assessment (GA) is an important tool in the management of older cancer patients; however, its primary clinical use has been in the outpatient setting. During an unplanned hospitalization, patients are extremely frail and are most likely to benefit from GA. This study demonstrates that hospitalized older adults with cancer have high levels of functional deficits on GA. These deficits are under-recognized and poorly managed by hospital-based clinicians in a tertiary care setting. Incorporation of GA measures during a hospital stay is a way to improve outcomes in this population. ©AlphaMed Press.

Entities:  

Keywords:  Geriatric assessment; Geriatric oncology; Inpatient; Readmission

Mesh:

Year:  2015        PMID: 26032136      PMCID: PMC4492242          DOI: 10.1634/theoncologist.2015-0023

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  30 in total

1.  Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay.

Authors:  Joseph T Hanlon; Carl F Pieper; Emily R Hajjar; Richard J Sloane; Catherine I Lindblad; Christine M Ruby; Kenneth E Schmader
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2006-05       Impact factor: 6.053

2.  Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study.

Authors:  Arti Hurria; Kayo Togawa; Supriya G Mohile; Cynthia Owusu; Heidi D Klepin; Cary P Gross; Stuart M Lichtman; Ajeet Gajra; Smita Bhatia; Vani Katheria; Shira Klapper; Kurt Hansen; Rupal Ramani; Mark Lachs; F Lennie Wong; William P Tew
Journal:  J Clin Oncol       Date:  2011-08-01       Impact factor: 44.544

3.  Developing a cancer-specific geriatric assessment: a feasibility study.

Authors:  Arti Hurria; Supriya Gupta; Marjorie Zauderer; Enid L Zuckerman; Harvey J Cohen; Hyman Muss; Miriam Rodin; Katherine S Panageas; Jimmie C Holland; Leonard Saltz; Mark G Kris; Ariela Noy; Jorge Gomez; Ann Jakubowski; Clifford Hudis; Alice B Kornblith
Journal:  Cancer       Date:  2005-11-01       Impact factor: 6.860

4.  Comprehensive geriatric assessment adds information to Eastern Cooperative Oncology Group performance status in elderly cancer patients: an Italian Group for Geriatric Oncology Study.

Authors:  Lazzaro Repetto; Lucia Fratino; Riccardo A Audisio; Antonella Venturino; Walter Gianni; Marina Vercelli; Stefano Parodi; Denise Dal Lago; Flora Gioia; Silvio Monfardini; Matti S Aapro; Diego Serraino; Vittorina Zagonel
Journal:  J Clin Oncol       Date:  2002-01-15       Impact factor: 44.544

5.  Geriatric syndromes in elderly patients admitted to an oncology-acute care for elders unit.

Authors:  Kellie L Flood; Maria B Carroll; Cyndi V Le; Linda Ball; Debbie A Esker; David B Carr
Journal:  J Clin Oncol       Date:  2006-05-20       Impact factor: 44.544

6.  Geriatric evaluation and management units in the care of the frail elderly cancer patient.

Authors:  Arati V Rao; Frank Hsieh; John R Feussner; Harvey Jay Cohen
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2005-06       Impact factor: 6.053

7.  Future of cancer incidence in the United States: burdens upon an aging, changing nation.

Authors:  Benjamin D Smith; Grace L Smith; Arti Hurria; Gabriel N Hortobagyi; Thomas A Buchholz
Journal:  J Clin Oncol       Date:  2009-04-29       Impact factor: 44.544

8.  Pre-operative assessment of cancer in the elderly (PACE): a comprehensive assessment of underlying characteristics of elderly cancer patients prior to elective surgery.

Authors:  D Pope; H Ramesh; R Gennari; G Corsini; M Maffezzini; H J Hoekstra; D Mobarak; K Sunouchi; A Stotter; C West; R A Audisio
Journal:  Surg Oncol       Date:  2006-12       Impact factor: 3.279

9.  Management of Frail and Not-Frail elderly cancer patients in a hospital-based geriatric oncology program.

Authors:  Umberto Basso; Singora Tonti; Catia Bassi; Antonella Brunello; Lara Maria Pasetto; Daniela Scaglione; Cristina Falci; Manuela Beda; Savina Maria Luciana Aversa; Micaela Stefani; Eugenio Castegnaro; Fabio Tamellini; Silvio Monfardini
Journal:  Crit Rev Oncol Hematol       Date:  2008-02-19       Impact factor: 6.312

10.  Co-morbidity and functional deficits independently contribute to quality of life before chemotherapy in elderly cancer patients.

Authors:  Ulrich Wedding; Bernd Röhrig; Almuth Klippstein; Christina Brix; Ludger Pientka; Klaus Höffken
Journal:  Support Care Cancer       Date:  2007-02-21       Impact factor: 3.359

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  8 in total

1.  A Randomized Trial of Real-Time Geriatric Assessment Reporting in Nonelectively Hospitalized Older Adults with Cancer.

Authors:  Trevor A Jolly; Allison M Deal; Caroline Mariano; Nicole Markowski; Sharanda Kirk; Max S Perlmutt; Franklin Jones; Suel Ki Choi; Kirsten A Nyrop; Jan Busby-Whitehead; Hyman Muss
Journal:  Oncologist       Date:  2020-01-27

Review 2.  Polypharmacy in the Geriatric Oncology Population.

Authors:  Lauren R Hersh; Kathryn Beldowski; Emily R Hajjar
Journal:  Curr Oncol Rep       Date:  2017-09-23       Impact factor: 5.075

Review 3.  Falls in older adults with cancer: a systematic review of prevalence, injurious falls, and impact on cancer treatment.

Authors:  Schroder Sattar; Shabbir M H Alibhai; Sandra L Spoelstra; Rouhi Fazelzad; Martine T E Puts
Journal:  Support Care Cancer       Date:  2016-07-22       Impact factor: 3.603

4.  The Perceptions and Expectations of Older Women in the Establishment of the Senior Women's Breast Cancer Clinic (SWBCC): a Needs Assessment Study.

Authors:  Michael C Tjong; Ines Menjak; Maureen Trudeau; Rajin Mehta; Frances Wright; Angela Leahey; Janet Ellis; Damian Gallagher; Leslie Gibson; Bonnie Bristow; Katie Rice; Ewa Szumacher
Journal:  J Cancer Educ       Date:  2017-12       Impact factor: 2.037

5.  Predictors of Unplanned Hospitalizations Among Older Adults Receiving Cancer Chemotherapy.

Authors:  Heidi D Klepin; Can-Lan Sun; David D Smith; Rawad Elias; Kelly M Trevino; Ashley Leak Bryant; Daneng Li; Christian Nelson; William P Tew; Supriya G Mohile; Ajeet Gajra; Cynthia Owusu; Cary Gross; Stuart M Lichtman; Vani V Katheria; Hyman B Muss; Andrew E Chapman; Harvey Jay Cohen; Arti Hurria; William Dale
Journal:  JCO Oncol Pract       Date:  2021-04-21

Review 6.  Assessing the Functional Status of Older Cancer Patients in an Ambulatory Care Visit.

Authors:  Janine Overcash
Journal:  Healthcare (Basel)       Date:  2015-09-18

7.  Comorbidity, Physical Function, and Quality of Life in Older Adults with Acute Myeloid Leukemia.

Authors:  Susan Storey; Tamryn Fowler Gray; Ashley Leak Bryant
Journal:  Curr Geriatr Rep       Date:  2017-10-11

8.  A simple test-based frailty index to predict survival among cancer patients with an unplanned hospitalization: An observational cohort study.

Authors:  Timothy Hembree; Olga Theou; Sarah Thirlwell; Richard R Reich; Biwei Cao; Marina Sehovic; Misbahuddin Syed; Neha Verma; Thu-Cuc Nguyen; Dinesh Keerty; Jaqueline Wesolow; Viktoriya Koverzhenko; Martine Extermann; Jessica Huang; Asha Ramsakal
Journal:  Cancer Med       Date:  2021-08-05       Impact factor: 4.452

  8 in total

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