Literature DB >> 31985125

A Randomized Trial of Real-Time Geriatric Assessment Reporting in Nonelectively Hospitalized Older Adults with Cancer.

Trevor A Jolly1, Allison M Deal2, Caroline Mariano3, Nicole Markowski2, Sharanda Kirk2, Max S Perlmutt2, Franklin Jones2, Suel Ki Choi4, Kirsten A Nyrop1, Jan Busby-Whitehead5, Hyman Muss1,2.   

Abstract

BACKGROUND: Hospitalized older adults have significant geriatric deficits that may lead to poor outcomes. We conducted a randomized trial to investigate the effectiveness of providing clinicians with a real-time geriatric assessment (GA) report in nonelectively hospitalized older patients with cancer. SUBJECTS, MATERIALS, AND METHODS: We developed a web-based software platform for administering a modified GA (Cancer 2005;104:1998-2005) to older (>70 years) nonelectively hospitalized patients with pathologically confirmed malignancy. Patients were randomized to have their GA report provided to their treating clinicians (Intervention arm) or not provided (Control arm).
RESULTS: Our study included 135 patients, median age 76 years, 52% female, 75% white, 21% black, 79% greater than high school education, 59% married, and 17% living alone. All patients had at least one GA-identified deficit, including physical function deficits (90%), cognitive impairment (22%), >5 comorbidities (28%), polypharmacy (>9 medications; 38%), weight loss ≥10% in the past 6 months (40%), anxiety (32%), or depression (30%). There was no difference between the Intervention (6%) and Control arms (9%) in the proportion of patients who were referred by their clinical team for an intervention to address a deficit (p = .53).
CONCLUSION: Many older nonelectively hospitalized patients with cancer have geriatric deficits that are amenable to evidence-based interventions. Real-time GA reports provided to the care team prior to discharge did not influence provider referral for such interventions. There is a need for systems-level interventions to address deficits in this vulnerable patient population. IMPLICATIONS FOR PRACTICE: Geriatric deficits are common in hospitalized older adults with cancer and lead to poor outcomes. Addressing modifiable deficits represents an appealing way to improve outcomes. Widespread geriatrician consultation is impractical owing to resource and personnel constraints. This work tested whether prompt delivery of a mostly self-administered, web-based geriatric assessment report to clinicians improved referral rates for evidence-informed interventions. It confirmed frequent geriatric deficits and high readmission rates in this population but found that real-time geriatric assessment reporting did not influence provider referral for evidence-informed interventions on geriatric assessment identified deficits. These findings highlight the need for systems-level intervention to improve outcomes in this vulnerable patient population. © AlphaMed Press 2020.

Entities:  

Keywords:  Cancer and aging; Geriatric assessment; Geriatric oncology

Mesh:

Year:  2020        PMID: 31985125      PMCID: PMC7288650          DOI: 10.1634/theoncologist.2019-0581

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  15 in total

1.  Falls in Older Adults With Cancer: Evaluation by Oncology Providers.

Authors:  Emily J Guerard; Allison M Deal; Grant R Williams; Trevor A Jolly; Kirsten A Nyrop; Hyman B Muss
Journal:  J Oncol Pract       Date:  2015-07-14       Impact factor: 3.840

2.  Developing a cancer-specific geriatric assessment: a feasibility study.

Authors:  Arti Hurria; Supriya Gupta; Marjorie Zauderer; Enid L Zuckerman; Harvey J Cohen; Hyman Muss; Miriam Rodin; Katherine S Panageas; Jimmie C Holland; Leonard Saltz; Mark G Kris; Ariela Noy; Jorge Gomez; Ann Jakubowski; Clifford Hudis; Alice B Kornblith
Journal:  Cancer       Date:  2005-11-01       Impact factor: 6.860

3.  Functional decline in older adults one year after hospitalization.

Authors:  Anne-Sofie Helvik; Geir Selbæk; Knut Engedal
Journal:  Arch Gerontol Geriatr       Date:  2013-06-24       Impact factor: 3.250

4.  Prognostic value of geriatric assessment in older patients with advanced breast cancer receiving chemotherapy.

Authors:  A A Aaldriks; E J Giltay; S le Cessie; L G M van der Geest; J E A Portielje; B C Tanis; J W R Nortier; E Maartense
Journal:  Breast       Date:  2013-02-14       Impact factor: 4.380

5.  Quality of life of older patients with early-stage breast cancer receiving adjuvant chemotherapy: a companion study to cancer and leukemia group B 49907.

Authors:  Alice B Kornblith; Lan Lan; Laura Archer; Ann Partridge; Gretchen Kimmick; Clifford Hudis; Eric Winer; Rebecca Casey; Samantha Bennett; Harvey Jay Cohen; Hyman B Muss
Journal:  J Clin Oncol       Date:  2011-02-07       Impact factor: 44.544

6.  The feasibility of inpatient geriatric assessment for older adults receiving induction chemotherapy for acute myelogenous leukemia.

Authors:  Heidi D Klepin; Ann M Geiger; Janet A Tooze; Stephen B Kritchevsky; Jeff D Williamson; Leslie R Ellis; Denise Levitan; Timothy S Pardee; Scott Isom; Bayard L Powell
Journal:  J Am Geriatr Soc       Date:  2011-09-13       Impact factor: 5.562

7.  Improving the quality of life of geriatric cancer patients with a structured multidisciplinary intervention: a randomized controlled trial.

Authors:  Maria I Lapid; Teresa A Rummans; Paul D Brown; Marlene H Frost; Mary E Johnson; Mashele M Huschka; Jeff A Sloan; Jarrett W Richardson; Jean M Hanson; Matthew M Clark
Journal:  Palliat Support Care       Date:  2007-06

8.  Geriatric assessment-identified deficits in older cancer patients with normal performance status.

Authors:  Trevor A Jolly; Allison M Deal; Kirsten A Nyrop; Grant R Williams; Mackenzi Pergolotti; William A Wood; Shani M Alston; Brittaney-Belle E Gordon; Samara A Dixon; Susan G Moore; W Chris Taylor; Michael Messino; Hyman B Muss
Journal:  Oncologist       Date:  2015-03-12

9.  Patterns of care and survival in cancer patients with cognitive impairment.

Authors:  Claire Robb; David Boulware; Janine Overcash; Martine Extermann
Journal:  Crit Rev Oncol Hematol       Date:  2009-08-26       Impact factor: 6.312

10.  Management of Frail and Not-Frail elderly cancer patients in a hospital-based geriatric oncology program.

Authors:  Umberto Basso; Singora Tonti; Catia Bassi; Antonella Brunello; Lara Maria Pasetto; Daniela Scaglione; Cristina Falci; Manuela Beda; Savina Maria Luciana Aversa; Micaela Stefani; Eugenio Castegnaro; Fabio Tamellini; Silvio Monfardini
Journal:  Crit Rev Oncol Hematol       Date:  2008-02-19       Impact factor: 6.312

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  4 in total

Review 1.  Informational support for depression and quality of life improvements in older patients with cancer: a systematic review and meta-analysis.

Authors:  Wenwen Yang; Guiling Geng; Jianing Hua; Min Cui; Zihan Geng
Journal:  Support Care Cancer       Date:  2021-08-20       Impact factor: 3.359

2.  Risk Factors for Hospitalizations Among Older Adults with Gastrointestinal Cancers.

Authors:  Daneng Li; Can-Lan Sun; Rebecca Allen; Christiana J Crook; Abrahm Levi; Richard Ballena; Heidi D Klepin; Rawad Elias; Supriya G Mohile; William P Tew; Cynthia Owusu; Hyman B Muss; Stuart M Lichtman; Cary P Gross; Andrew E Chapman; Ajeet Gajra; Harvey J Cohen; Vani Katheria; Arti Hurria; William Dale
Journal:  Oncologist       Date:  2022-02-03

3.  Geriatric assessment and management with question prompt list using a web-based application for elderly patients with cancer (MAPLE) to communicate ageing-related concerns: J-SUPPORT 2101 study protocol for a multicentre, parallel group, randomised controlled trial.

Authors:  Ayumu Matsuoka; Maiko Fujimori; Boku Narikazu; Atsuo Takashima; Takuji Okusaka; Keita Mori; Tatsuo Akechi; Taichi Shimazu; Ayumi Okizaki; Tempei Miyaji; Yoshiyuki Majima; Fumio Nagashima; Yosuke Uchitomi
Journal:  BMJ Open       Date:  2022-09-26       Impact factor: 3.006

4.  A simple test-based frailty index to predict survival among cancer patients with an unplanned hospitalization: An observational cohort study.

Authors:  Timothy Hembree; Olga Theou; Sarah Thirlwell; Richard R Reich; Biwei Cao; Marina Sehovic; Misbahuddin Syed; Neha Verma; Thu-Cuc Nguyen; Dinesh Keerty; Jaqueline Wesolow; Viktoriya Koverzhenko; Martine Extermann; Jessica Huang; Asha Ramsakal
Journal:  Cancer Med       Date:  2021-08-05       Impact factor: 4.452

  4 in total

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