Literature DB >> 26027482

Genome sequence analysis of Ebola virus in clinical samples from three British healthcare workers, August 2014 to March 2015.

A Bell1, K Lewandowski, R Myers, D Wooldridge, E Aarons, A Simpson, R Vipond, M Jacobs, S Gharbia, M Zambon.   

Abstract

We determined complete viral genome sequences from three British healthcare workers infected with Ebola virus (EBOV) in Sierra Leone, directly from clinical samples. These sequences closely resemble those previously observed in the current Ebola virus disease outbreak in West Africa, with glycoprotein and polymerase genes showing the most sequence variation. Our data indicate that current PCR diagnostic assays remain suitable for detection of EBOV in this epidemic and provide confidence for their continued use in diagnosis.

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Year:  2015        PMID： 26027482     DOI： 10.2807/1560-7917.es2015.20.20.21131

Source DB:  PubMed          Journal:  Euro Surveill        ISSN： 1025-496X


  8 in total

Review 1.  The evolution of Ebola virus: Insights from the 2013-2016 epidemic.

Authors:  Edward C Holmes; Gytis Dudas; Andrew Rambaut; Kristian G Andersen
Journal:  Nature       Date:  2016-10-13       Impact factor: 49.962

2.  Evolution and Spread of Ebola Virus in Liberia, 2014-2015.

Authors:  Jason T Ladner; Michael R Wiley; Suzanne Mate; Gytis Dudas; Karla Prieto; Sean Lovett; Elyse R Nagle; Brett Beitzel; Merle L Gilbert; Lawrence Fakoli; Joseph W Diclaro; Randal J Schoepp; Joseph Fair; Jens H Kuhn; Lisa E Hensley; Daniel J Park; Pardis C Sabeti; Andrew Rambaut; Mariano Sanchez-Lockhart; Fatorma K Bolay; Jeffrey R Kugelman; Gustavo Palacios
Journal:  Cell Host Microbe       Date:  2015-12-09       Impact factor: 21.023

Review 3.  Genomic Analysis of Viral Outbreaks.

Authors:  Shirlee Wohl; Stephen F Schaffner; Pardis C Sabeti
Journal:  Annu Rev Virol       Date:  2016-08-03       Impact factor: 10.431

4.  Virus Variation Resource - improved response to emergent viral outbreaks.

Authors:  Eneida L Hatcher; Sergey A Zhdanov; Yiming Bao; Olga Blinkova; Eric P Nawrocki; Yuri Ostapchuck; Alejandro A Schäffer; J Rodney Brister
Journal:  Nucleic Acids Res       Date:  2016-11-28       Impact factor: 16.971

5.  Bayesian estimation of past population dynamics in BEAST 1.10 using the Skygrid coalescent model.

Authors:  Verity Hill; Guy Baele
Journal:  Mol Biol Evol       Date:  2019-07-31       Impact factor: 16.240

6.  Late Ebola virus relapse causing meningoencephalitis: a case report.

Authors:  Michael Jacobs; Alison Rodger; David J Bell; Sanjay Bhagani; Ian Cropley; Ana Filipe; Robert J Gifford; Susan Hopkins; Joseph Hughes; Farrah Jabeen; Ingolfur Johannessen; Drosos Karageorgopoulos; Angie Lackenby; Rebecca Lester; Rebecca S N Liu; Alisdair MacConnachie; Tabitha Mahungu; Daniel Martin; Neal Marshall; Stephen Mepham; Richard Orton; Massimo Palmarini; Monika Patel; Colin Perry; S Erica Peters; Duncan Porter; David Ritchie; Neil D Ritchie; R Andrew Seaton; Vattipally B Sreenu; Kate Templeton; Simon Warren; Gavin S Wilkie; Maria Zambon; Robin Gopal; Emma C Thomson
Journal:  Lancet       Date:  2016-05-18       Impact factor: 79.321

7.  Estimating Epidemic Incidence and Prevalence from Genomic Data.

Authors:  Timothy G Vaughan; Gabriel E Leventhal; David A Rasmussen; Alexei J Drummond; David Welch; Tanja Stadler
Journal:  Mol Biol Evol       Date:  2019-08-01       Impact factor: 16.240

8.  On-Demand Patient-Specific Phenotype-to-Genotype Ebola Virus Characterization.

Authors:  Brett F Beitzel; Sheli R Radoshitzky; Nicholas Di Paola; Jennifer M Brannan; David Kimmel; Katie Caviness; Veronica Soloveva; Shuiqing Yu; Elena N Postnikova; Courtney L Finch; Hu Liu; Laura Prugar; Russell Bakken; John M Dye; Jeffrey R Kugelman; James M Cunningham; Mariano Sanchez-Lockhart; Jens H Kuhn; Gustavo Palacios
Journal:  Viruses       Date:  2021-10-06       Impact factor: 5.048
  8 in total

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